Pyogenic Liver Abscess: Diagnostic and Therapeutic Management

Rosa, Otto Mauro dos Santos; Lunardelli, Henrique Simonsen; Ribeiro-Júnior, Marcelo Augusto Fontenelle

doi:10.1590/0102-6720201600030015

Cited by 38 publications

(39 citation statements)

References 14 publications

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“…Mortality Rate Mangukiya et al (10) 1.5% Peris et al (12) 8.2% Santos Rosa et al (3) 20% Present study 8% Outcome of Liver Abscess…”

Section: Studiesmentioning

confidence: 75%

“…Mangukiya et al (10) Santos Rosa et al (3) Chaudhary et al (5) Present Study (9) Jha et al (5) Santos Rosa et al (2) (11) Peris et al (12) Kong et al (13) (6) 88% Amoebic Serology…”

Section: Symptommentioning

confidence: 97%

“…There were 45 (90%) males and 5 (10%) females. (3) 70% 30% Venu Gopal et al (4) 65.1% Chaudhary et al (5) 31-60 19-69 Jha et al (6) 21-50 2. (9) Mostly…”

Section: Demographic Featuresmentioning

confidence: 99%

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Clinicopathological Study of Liver Abscess in Eastern Indian Population

Roy¹,

Ranjan²

2018

jemds

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BACKGROUND A descriptive study of Liver abscess is defined as collection of purulent material in liver parenchyma. It could be amoebic, pyogenic, infected hydatid, traumatic or ascaridal. It is a burning problem in tropical nations with often lethal consequences and diagnostic/therapeutic challenges. This study aims to find out the demographic distribution, different modes of presentations, risk factors association, alteration of various laboratory and radiological investigations in diagnosis of liver abscess and responses to standard institutional management strategies. MATERIALS AND METHODS Medical records were taken by preformed case, Proforma. Descriptive statistics were used and analysed by SPSS software. RESULTS 3/4th of cases belonged to 4th to 6th decade. Males were more commonly affected than females. Alcoholism was the most consistent risk factor followed by diabetes mellitus. Most common presenting symptom and sign were abdominal pain and abdominal tenderness in right hypochondriac region respectively. Most common aetiology of liver abscess was amoebic followed by mixed amoebic and pyogenic infections. The most common organisms obtained from pus C/S from liver abscess were Enterococcus spp. and Escherichia coli. Abnormal chest x-ray findings were recorded in > 50% of cases. USG showed majority of cases had large, solitary liver abscess in right lobe of liver. Most common complication observed was intraabdominal rupture of liver abscess, for which open surgical drainage was performed. CONCLUSION Recurrence was observed more following conservative management than other modalities.

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“…Mortality Rate Mangukiya et al (10) 1.5% Peris et al (12) 8.2% Santos Rosa et al (3) 20% Present study 8% Outcome of Liver Abscess…”

Section: Studiesmentioning

confidence: 75%

“…Mangukiya et al (10) Santos Rosa et al (3) Chaudhary et al (5) Present Study (9) Jha et al (5) Santos Rosa et al (2) (11) Peris et al (12) Kong et al (13) (6) 88% Amoebic Serology…”

Section: Symptommentioning

confidence: 97%

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Clinicopathological Study of Liver Abscess in Eastern Indian Population

Roy¹,

Ranjan²

2018

jemds

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“…2,4 Clinical features noted by us have also been present in other studies. 3,8 LA was more common in right lobe. It may be due to anatomic reasons.…”

Section: Discussionmentioning

confidence: 89%

Comparative evaluation of interventional radiology modalities in treatment of liver abscess

Pandey

Srivastava

2018

Int Surg J

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Background: Liver abscess (LA) is a superlative cavity in the liver resulting from the invasion and multiplication of microorganism. With progress of interventional radiology, alternative to surgery in form of percutaneous drainage (PD) have become popular. PD can be accomplished by either percutaneous catheter drainage (PCD) or percutaneous needle aspiration (PCNA). This study was conducted to assess the PD as a definitive treatment modality for LA and comparison of PCD and PCNA.Methods: The study was conducted in the Radiodiagnosis Department. All patients of LA were evaluated for age, sex, duration of complaints, type of intervention performed, and outcome etc. After diagnosis, patients were managed by PCD or PCNA. Response to treatment, duration of stay, and overall success of both the modalities were evaluated.Results: The duration of this study was 34 months. During this period, 57 patients were evaluated. Of total, 29 underwent PCD and 28 PCNA. Male to female ratio was 2:1. Right lobe was involved in 48. Mean volume of abscess cavity was 356.44 ml. All patients who underwent PCD responded to the treatment; however, 8 patients who were treated by PCNA did not respond completely. Outcome was statistically related to type of treatment modality. PCD was statistically superior to PCNA (P <0.05).Conclusions: PD may be regarded as first line of treatment for LA. It appears that PCD is better as compared to PCNA for successful outcome of patients.

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“…Nuclear magnetic resonance (NMR) imaging is a more expensive technique that does not generate radiation for the patient. It is useful when there is evidence of biliary disease or involvement of the hepatic veins, helping to determine if the aetiology has a biliary origin 29 30…”

Section: Pyogenic Liver Abscessmentioning

confidence: 99%