Pyogenic liver abscesses in adults: A 3-year study

Korumilli, Ramesh Kumar; Ginjala, Gautham R; Mahesh, Srinivas A

doi:10.4103/2278-9596.136709

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“…About 2/3 of cases of hepatic abscess in developing countries are amoebic in origin and ¾ of cases in developed countries are pyogenic 13 . The predominant organism cultured from our patients' hepatic abscesses was Staphylococcus aureus, which is the most common pyogenic cause in children 14 , in contrast to Escherichia coli and Klebsiella pneumonia in adults 18,19 . Likewise, there was monomicrobial growth in blood culture of our patients with Staphylococcus aureus.…”

Section: Discussionmentioning

confidence: 81%

Clinical Profile and Factors Affecting Outcome of Children with Hepatic Abscess: 19 Year Study

Lu¹,

Nolasco²,

Tan³

2018

PIDSPJ

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Objectives: To describe the clinical profile of children with hepatic abscess, determine their laboratory & imaging findings, medical and surgical treatments and study factors affecting its outcome. Methodology: A retrospective cohort study done in December 2016 on children 0 to Demographic, clinical and diagnostic data were correlated with the outcome and presence of complications. Results: Thirty cases were identified in 19 years but only 25 charts were available for review. Mean age in years was 5.27 +/- 4.80 SD with male predominance. Fever (96%) and abdominal pain (60%) were common symptoms.Only 9 patients had hepatic abscess culture with Staphylococcus aureus (56%) as the most frequent growth. Anemia (76%) and leukocytosis (96%), and solitary (76%), large abscess >5 cms (60%) involving the right lobe (72%), were the common diagnostic findings. Most were treated with antibiotics alone (60%).All patients improved with no mortality noted, while pleural effusion was seen in 8 out of 12 patients with complications. Only male gender was significantly associated with complications both on chi-square (p0.004) and logistic regression (p 0.008). Conclusion: Hepatic abscess is a liver infection usually seen among young and male population, manifesting as fever with anemia and leucocytosis. Most were complicated by pleural effusion with no deaths reported. Male gender had significant association with complications.

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