Pyostomatitis vegetans: report of three cases and review of the literature

Thornhill, Martin H.; Zakrzewska, Joanna M.; Gilkes, J. J. H.

doi:10.1111/j.1600-0714.1992.tb00996.x

Cited by 49 publications

(58 citation statements)

References 21 publications

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“…Of these 19 (67%) were diagnosed with ulcerative colitis [2, 3, 5, 7, 9-11, 13-19, 21-28], and 4 (11%) with Crohn disease [4,6,8,20]. In most cases the bowel disease appears to precede the onset of the oral lesions by months or years [10,22], and the severity of oral disease frequently tends to parallel the activity of the bowel disease [4,5,22,25]. However, in some cases gastro-intestinal disturbances is so minimal that it may remain undetected unless the patient is directly questioned about symptoms and the bowel specifically investigated [4,7].…”

Section: Discussionmentioning

confidence: 98%

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Pyostomatitis vegetans in childhood

et al. 1998

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Section: Discussionmentioning

confidence: 98%

“…It has a distinct clinical appearance with multiple pustules, erosions and ulcers, on a diffuse erythematous background and may exhibit vegetations and folding [25]. The lesions predominantly affect the labial gingivae and buccal mucosae [10].…”

Section: Introductionmentioning

confidence: 99%

Pyostomatitis vegetans in childhood

et al. 1998

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“…En effet, ce taux semble augmenter en période de poussées de la maladie et diminuer en réponse à l'initiation d'une thérapeutique systémique avec une amélio-ration clinique concomitante [13,14]. Dans le cas présenté, aucune polynucléose éosinophile n'a été observée.…”

Section: Discussionunclassified

Pyostomatite végétante de la muqueuse orale : cas clinique et revue de la littérature

Guillerminet

Lepreux

Mittler

et al. 2015

Med Buccale Chir Buccale

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-Pyostomatitis vegetans: case report and literature review. Introduction: Pyostomatitis vegetans is a rare dermatosis which is manifested by yellowish-white pustules and inflammatory vesiculous lesions of the oral mucosa in the gum, the vestibule, the soft and hard palate, and sometimes the lips. PV is often associated with inflammatory bowel chronic diseases (IBDs) such as ulcerative colitis and Crohn's disease. Observation: An 80-year-old patient with Crohn's disease consulted for linear ulceration localized on the lower labial vestibule of the left cheek and on the right upper vestibule. The PV diagnosis was made after biopsy and the lesions regressed under local corticosteroid application. Discussion: The characteristic symptoms and histology (negative direct and indirect immunofluorescence) enable the diagnosis of PV and eliminate pemphigus vegetans and pyoderma gangrenosum. Peripheral eosinophilia and eosinophils on a histological section may be useful for monitoring disease activity. Treatment is based on local or systemic corticosteroids depending on the intensity of the oral and gastrointestinal involvement. Conclusion: Upon discovery of PV lesions, testing for IBDs is critical in order to establish a treatment as early as possible.

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“…Peripheral eosinophilia is a common finding and may help differentiate PV from other blistering dermatoses. 5 The diagnosis of PV is based on the combination of typical appearance, association with IBD, peripheral eosinophilia, negative culture, and histological findings. 4 The mainstay of management is to treat the underlying IBD and resolution after colectomy has been reported.…”

Section: Case Reportmentioning

confidence: 99%