Pyrazinamide-induced lichenoid photodermatitis

Choonhakarn, Charoen; Janma, Jirayut

doi:10.1016/s0190-9622(99)70459-7

Cited by 23 publications

(10 citation statements)

References 8 publications

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“…EMB has been reported as the most common anti-Tb agent responsible for LDE. Previous reports indicated that the latent period between exposure and development of LDE is 3-6 months for EMB, 1,13 1.5 months for pyrazinamide, 13,14 and a few days for rifampicin. 9 Blood eosinophilia has been reported in some cases.…”

Section: Discussionmentioning

confidence: 96%

“…9 Blood eosinophilia has been reported in some cases. 9,13,14 In the Korean literature, of 8 cases of LDE, 5 were induced by anti-Tb drugs showed blood eosinophilia and 2 showed Wickham striae. 13 LDE is typically resolved simply by cessation of the causative drugs, and thus LDE should be considered when patients receiving anti-Tb treatment present with blood eosinophilia and typical hyperkeratotic skin lesions with scales.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A Case of Cycloserine-Induced Lichenoid Drug Eruption Supported by the Lymphocyte Transformation Test

Kim

Park

Jung

et al. 2017

Allergy Asthma Immunol Res

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This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.Lichenoid drug eruption (LDE) is a rare form of delayed-type drug eruption. Among anti-tuberculosis (Tb) agents, cycloserine (CS) has been reported as a rare cause of LDE. Positive results on the lymphocyte transformation test (LTT) have not been reported in patients with LDE. In the present case, we performed LTT and a patch test, and successfully proved CS as the offending drug in this patient, who had been treated with multiple anti-Tb drugs. These observations suggest that CS should be considered a possible cause of LDE and that LTT can be an option for the diagnosis of LDE.

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

A Case of Cycloserine-Induced Lichenoid Drug Eruption Supported by the Lymphocyte Transformation Test

Kim

Park

Jung

et al. 2017

Allergy Asthma Immunol Res

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show abstract

“…EMB has been reported as the most common anti-Tb agent responsible for LDE. Previous reports indicated that the latent period between exposure and development of LDE is 3-6 months for EMB,113 1.5 months for pyrazinamide,1314 and a few days for rifampicin 9. Blood eosinophilia has been reported in some cases 91314.…”

Section: Discussionmentioning

confidence: 99%

A Case of Cycloserine-Induced Lichenoid Drug Eruption Supported by the Lymphocyte Transformation Test

Kim

ShinYoung

Jung

et al. 2017

Allergy Asthma Immunol Res

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Lichenoid drug eruption (LDE) is a rare form of delayed-type drug eruption. Among anti-tuberculosis (Tb) agents, cycloserine (CS) has been reported as a rare cause of LDE. Positive results on the lymphocyte transformation test (LTT) have not been reported in patients with LDE. In the present case, we performed LTT and a patch test, and successfully proved CS as the offending drug in this patient, who had been treated with multiple anti-Tb drugs. These observations suggest that CS should be considered a possible cause of LDE and that LTT can be an option for the diagnosis of LDE.

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“…The time period between the initiation of drug and onset of rash ranges from days to years, with most cases occurring within 2 months . Isoniazid, pyrazinamide, ethambutol, and rifampicin all have been reported to cause LDR (Table 1; Choonhakarn & Janma, 1999;Grossman, Warren, Mady, & Satra, 1995;Sharma et al, 2001). Oral mucosa involvement is rare (Garg, Gore, Jain, & Kumar, 2015).…”

Section: Discussionmentioning

confidence: 99%

Lichenoid drug reaction due to anti‐tubercular therapy presenting as erythroderma

Katare

Arora

Sardana

et al. 2019

Dermatologic Therapy

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First-line anti-tubercular therapy (ATT) is very effective in management of tuberculosis and is usually well tolerated. Varied spectrum of cutaneous adverse drug reactions is associated with ATT, of which lichenoid drug eruption (LDR) constitutes approximately 10% of the cases. However, LDR presenting as erythroderma is very rare. Here, we report a case of exfoliative dermatitis secondary to LDR which developed after 5 months of ATT. K E Y W O R D Sdrug reaction, erythroderma

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Pyrazinamide-induced lichenoid photodermatitis

Cited by 23 publications

References 8 publications

A Case of Cycloserine-Induced Lichenoid Drug Eruption Supported by the Lymphocyte Transformation Test

A Case of Cycloserine-Induced Lichenoid Drug Eruption Supported by the Lymphocyte Transformation Test

A Case of Cycloserine-Induced Lichenoid Drug Eruption Supported by the Lymphocyte Transformation Test

Lichenoid drug reaction due to anti‐tubercular therapy presenting as erythroderma

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