Pyridoxal Derived AIEgen for Fluorescence Turn-off Sensing of Cu2+ and Fe2+ Ions and Fluorescence Imaging of Latent Fingerprints

Coumarin‐Oxazolyl‐Based Chemosensor for Selective Detection of Fe2+ Ions: Preparation, Spectral Characterization, Theoretical Studies and Cellular Bioimaging

“…Further, to confirm the coordination nature of AOX with Fe 2 + ion, theoretical studies (DFT) were done by B3LYP level of theory which revealed the neutral tetradendate (N 2 O 2 ) coordination of AOX with Fe 2 + ion having the energy of 1.9 eV, which has more stabilisation than ONN tridentate coordination fashion of AOX with the energy of 2.1 eV. The cytotoxic nature of the probe AOX and AOX-Fe 2 + complex was investigated with HeLa cells and the compounds AOX and AOX-Fe 2 + possessed significant cytotoxic activity with the IC 50 Pyridoxal derived Fluorescence sensor 1.89 μM Latent Fingerprints [22] Benzophenone based fluorescence and Chemosensor 0.0363 μM Water Sample Analysis [48] Coumarin based Fluorescence sensor 45 nM Applications in living cells [49] Triarylimidazopyridine Scaffold based fluorescence and Colorimetric sensor…”

“…Umare et al . synthesized and analyzed the sensing ability of pyridoxal derived Schiff bases towards Fe 2+ ions with the binding constant of 1.23×10 5 M −1 [22] . Sharma et al .…”

“…[21] Umare et al synthesized and analyzed the sensing ability of pyridoxal derived Schiff bases towards Fe 2 + ions with the binding constant of 1.23×10 5 M À 1 . [22] Sharma et al utilized 2hydroxybenzhydrazone as probe for sensing Fe 2 + ions through colorimetric and fluorimetric techniques and additionally, its in vivo detection and bio-imaging of Fe 2 + in MDA-MB-231 cells were examined. [23] Quinoline and cellulose based fluorescent compound acted as suitable probe for the detection of Fe 3 + / Fe 2 + ion.…”

Aggregation-induced emission luminogens for latent fingerprint detection

“…Similar results were accomplished by another set of synthesized Schiff base derivatives of pyridoxal compounds, HSP (formed by condensation of pyridoxal with salicylaldehyde hydrazone) and NPPY (formed by condensation of pyridoxal with 2-hydroxy-1-hydrazone-naphthaldehyde). 54,55 HSP and NPPY could form yellow emitting self-aggregates, which adhere to sebum-rich papillary ridges of a fingerprint to provide second-level information on glass surfaces using UV light. 55 6.1.4.…”

Comment on the Paper “Water-Soluble Pyridine-Based Colorimetric Chemosensor for Naked Eye Detection of Silver Ions: Design, Synthesis, Spectral and Theoretical Investigation”, Anal. Methods 2014, 6, 9610-9614 by B. Annaraj and M. A. Neelakantan

“…However, this difference can be crucial because pyridoxal (PL) and pyridoxal 5'-phosphate (PLP) have different reactivity toward hydrazides. For example, the hydrazones of PLP can be prepared as simply as by uniting the warm aqueous solutions of aldehyde and hydrazide, while synthesis of PL-derived hydrazones required 1 h long refluxing of aldehyde and hydrazide mixture in methanol [7] or ethanol [8].…”