Pyroptosis induced by natural products and their derivatives for cancer therapy

Wen, Yingfei; Li, You; Li, Bin-bin; Liu, Peng; Qiu, Miaojuan; Li, Zihang; Xu, Jiaqi; Bi, Bo; Zhang, Shiqiang; Deng, Xinyi; Liu, Kaiyuan; Zhou, Shangbo; Wang, Qiang; Zhao, Jing

doi:10.1039/d4bm01023j

Biomater. Sci.

2024

DOI: 10.1039/d4bm01023j

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Pyroptosis induced by natural products and their derivatives for cancer therapy

Yingfei Wen,

You Li,

Bin-bin Li

et al.

Abstract: Natural products, known as compounds extracted and/or refined from plants and microbes in nature, have great potential in discovering therapeutic agents, especially for infectious diseases and cancer. In recent years,...

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Traditional Chinese medicine and its components effectively reduce resistance mediated by immune checkpoint inhibitors

Guo,

Fang,

2024

Front. Immunol.

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Immunotherapy has become a global focus in cancer treatment and research, with promising results from targeting immune checkpoints in tumors like non-small cell lung cancer, colon cancer, and melanoma. However, resistance to immune checkpoint inhibitors (ICIs) remains a significant challenge. Traditional Chinese medicine (TCM), known for its low toxicity and minimal side effects, shows promise in enhancing cancer treatment when combined with modern therapies. This study reviews recent research on ICIs resistance mechanisms and highlights TCM’s potential in overcoming this resistance, aiming to improve ICIs efficacy while minimizing toxicity.

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Traditional Chinese medicine and its components effectively reduce resistance mediated by immune checkpoint inhibitors

Guo,

Fang,

2024

Front. Immunol.

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Pyroptosis induced by natural products and their derivatives for cancer therapy

Abstract: Natural products, known as compounds extracted and/or refined from plants and microbes in nature, have great potential in discovering therapeutic agents, especially for infectious diseases and cancer. In recent years,...

Cited by 1 publication

References 157 publications

Traditional Chinese medicine and its components effectively reduce resistance mediated by immune checkpoint inhibitors

Traditional Chinese medicine and its components effectively reduce resistance mediated by immune checkpoint inhibitors

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