2011
DOI: 10.1134/s1819712411040167
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Pyrrole analogues of Phencyclidine decrease food and water consumption in mice

Abstract: Various studies have shown that Phencyclidine (1 [1 phenylcyciohexyl] piperidine, PCP, I) and many of its analogues demonstrate pharmacological effects. In this paper effects of some new pyrrole derivatives of, (1 [1 phenylcyclohexyl] pyrrole I, II, and 1 [1 [4 methylphenyl][cyclohexyl]] pyrrole III) on food and water intake in mice were investigated. Animals were deprived for 24 h before initial of each test for food and water intake evaluation. PCP and its derivatives were injected intraperitoneally (i.p.) a… Show more

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