Q Fever in the Basque Country: 1981-1984

Baranda, M. Montejo; Carranceja, J. Corral; Errasti, C. Aguirre

doi:10.1093/clinids/7.5.700

Cited by 58 publications

(28 citation statements)

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“…In other countries such as Australia, California and France [101], hepatitis and isolated or prolonged fever are the most common manifestations. In Spain and particularly in Catalonia [135] and in the Basque country [109,145], atypical pneumonia is mainly reported while in Andalusia [34,90,131] hepatitis and isolated or prolonged fever have been reported. The explanation of such differences is still unknown and could be due to differences of virulence between strains.…”

Section: Emerging/re-emerging Aspectmentioning

confidence: 99%

Is Q Fever an emerging or re-emerging zoonosis?

2005

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-Q fever is a zoonotic disease considered as emerging or re-emerging in many countries. It is caused by Coxiella burnetii, a bacterium developing spore-like forms that are highly resistant to the environment. The most common animal reservoirs are livestock and the main source of infection is by inhalation of contaminated aerosols. Although the culture process for Coxiella is laborious, advances on the knowledge of the life cycle of the bacterium have been made. New tools have been developed to (i) improve the diagnosis of Q fever in humans and animals, and especially animal shedders, (ii) perform epidemiological studies, and (iii) prevent the disease through the use of vaccines. This review summarizes the state of the knowledge on the bacteriology and clinical manifestations of Q fever as well as its diagnosis, epidemiology, treatment and prevention in order to understand what factors are responsible for its emergence or re-emergence. Coxiella burnetii / epidemiology / bacteriology / diagnostic / control

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Section: Emerging/re-emerging Aspectmentioning

confidence: 99%

Is Q Fever an emerging or re-emerging zoonosis?

2005

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“…There does appear to be geographic variation in frequency, with the organism virtually absent in some parts of Scandinavia [46], but second only to S. pneumoniae as a cause in e.g. North West Spain [68].…”

Section: Causative Pathogensmentioning

confidence: 99%

Community-acquired pneumonia in Europe: causative pathogens and resistance patterns

Woodhead¹

2002

Eur Respir J

183

117

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Community-acquired pneumonia (CAP) is a common condition affecting about 1/1,000 of the adult population per year. It occurs when bacteria enter the alveolar spaces of the lung initiating an inflammatory response which leads to the clinical features of cough, sputum production, breathlessness and sometimes chest pain and haemoptysis.At the end of the last century the causal relationship between bacteria and pneumonia was established and many of the early discoveries about the causes of CAP were made in Europe. Some 41 different prospective studies have established that ∼10 different microbial pathogens regularly cause CAP with occasional cases due to other rarer causes. The frequency of these organisms in Europe is similar in most countries, but there are some geographic differences. Differences in frequency are also apparent according to illness severity. It is generally recognised thatStreptococcus pneumoniaeis the most important causal bacterium in all countries.A relatively recent development has been the appearance and spread, in some of the common causative bacteria, of resistance to commonly used antibiotics to which they were once sensitive. The frequency of such resistance does vary markedly between European countries.However, published data is often difficult to interpret. The reasons for this are that the frequency of resistance varies according to the age of the patient, the site of the sample, the clinical diagnosis, the use of prior antibiotics and the influence of special groupse.g.those with cystic fibrosis. The impact ofin vitroantibiotic resistance on clinical outcome is still poorly understood, but recent studies are helping to clarify this issue and will be discussed.

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“…Pneumonia occurs less frequently with disease acquired from research facilities than with disease acquired from other sporadic exposures (50). Chest X rays are not always performed, but when they are, infiltrates involving the lower lobes are found in 4 to 75% of patients (8,19,47,58,70). Similarly, in various reports, Q fever is described as a rare or frequent cause of community-acquired pneumonias in general.…”

Section: Pathogenesismentioning

confidence: 99%

Q fever

Reimer

1993

Clin Microbiol Rev

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Q fever is an acute febrile illness first described in 1935 and now seen in many parts of the world. Human infection follows exposure to animals, especially domestic livestock. Recent outbreaks in metropolitan areas have implicated cats as the carrier of disease to humans. The etiologic agent, Coxiella burnetti, belongs to the family Rickettsiaceae, although it has distinct genetic characteristics and modes of transmission. Most recent attention has been focused on a number of large outbreaks of Q fever associated with medical research involving pregnant sheep. Although most infections are self-limited, some patients require prolonged treatment. Recent vaccines have had encouraging success in the prevention of disease in individuals at high risk of exposure.

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Q Fever in the Basque Country: 1981-1984

Cited by 58 publications

References 1 publication

Is Q Fever an emerging or re-emerging zoonosis?

Is Q Fever an emerging or re-emerging zoonosis?

Community-acquired pneumonia in Europe: causative pathogens and resistance patterns

Q fever

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