QEEG and LORETA in Teenagers With Conduct Disorder and Psychopathic Traits

Calzada-Reyes, Ana; Alvarez-Amador, Alfredo; Galán-García, Lídice; Valdés-Sosa, Mitchell

doi:10.1177/1550059416645712

Cited by 15 publications

(12 citation statements)

References 89 publications

(101 reference statements)

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“…High level of beta power can be observed in anxiety states (Beran, 2012), after intake of drugs such as benzodiazepines or barbiturates (Blume, 2006), after alcohol intake and is also common in children suffering from hyperactivity (Clarke et al, 2013). Recently, an excess of beta activity has also been observed in case of conduct disorder and psychopathic traits (Calzada-Reyes et al, 2016). Intake of psychotropic drug was denied by our subjects and thus the origin of abnormal beta band for these two subjects remains unclear.…”

Section: Discussionmentioning

confidence: 99%

A Pilot Study on the Effects of Transcranial Direct Current Stimulation on Brain Rhythms and Entropy during Self-Paced Finger Movement using the Epoc Helmet

Bodranghien

Mahe

Clément

et al. 2017

Front. Hum. Neurosci.

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Transcranial direct current stimulation (tDCS) of the cerebellum is emerging as a novel non-invasive tool to modulate the activity of the cerebellar circuitry. In a single blinded study, we applied anodal tDCS (atDCS) of the cerebellum to assess its effects on brain entropy and brain rhythms during self-paced sequential finger movements in a group of healthy volunteers. Although wearable electroencephalogram (EEG) systems cannot compete with traditional clinical/laboratory set-ups in terms of accuracy and channel density, they have now reached a sufficient maturity to envision daily life applications. Therefore, the EEG was recorded with a comfortable and easy to wear 14 channels wireless helmet (Epoc headset; electrode location was based on the 10–20 system). Cerebellar neurostimulation modified brain rhythmicity with a decrease in the delta band (electrode F3 and T8, p < 0.05). By contrast, our study did not show any significant change in entropy ratios and laterality coefficients (LC) after atDCS of the cerebellum in the 14 channels. The cerebellum is heavily connected with the cerebral cortex including the frontal lobes and parietal lobes via the cerebello-thalamo-cortical pathway. We propose that the effects of anodal stimulation of the cerebellar cortex upon cerebral cortical rhythms are mediated by this key-pathway. Additional studies using high-density EEG recordings and behavioral correlates are now required to confirm our findings, especially given the limited coverage of Epoc headset.

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Section: Discussionmentioning

confidence: 99%

A Pilot Study on the Effects of Transcranial Direct Current Stimulation on Brain Rhythms and Entropy during Self-Paced Finger Movement using the Epoc Helmet

Bodranghien

Mahe

Clément

et al. 2017

Front. Hum. Neurosci.

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“…In addition to empathy, antisocial behavior, including aggression, is also associated with dysfunctions in the prefrontal cortex [18][19][20][21][22][23][24]. Research shows that studies targeting the PFC with anodal tDCS can reduce social exclusion, and the aggressive behavior that emerges from this exclusion [68] can reduce unprovoked aggressive behavior [69] and reduce the intentions of aggressive behavior [70,71].…”

Section: Transcranial Direct Current Stimulationmentioning

confidence: 99%

“…Aggression is stated here as behavior that is mostly defined by any behavior that is intended to harm someone who is motivated to avoid being harmed [17]. As said before, antisocial behavior, especially aggression, is associated with dysfunctions in the prefrontal cortex [18][19][20][21][22][23][24]. In addition, research has highlighted the importance of executive functions -the "higher" cognitive functions that are controlled by the prefrontal cortex in control of aggression [25][26][27][28].…”

Section: Introductionmentioning

confidence: 99%

Transcranial Direct Current Stimulation (tDCS) as an intervention to improve empathic abilities and reduce violent behavior in forensic offenders: Study protocol for a randomized controlled trial.

Sergiou

Woods

Franken

et al. 2019

Preprint

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Background Recent studies show that changes in one of the brain areas related to empathic abilities (i.e. the Ventromedial Prefrontal Cortex (vmPFC)) plays an important role in violent behavior in abusers of alcohol and cocaine. According to the models of James Blair, empathy is a potential inhibitor of violent behavior. Individuals with less empathic abilities may be less susceptible and motivated to inhibit violent behavior, which causes a higher risk of violence. Recent neuroscientific research shows that modulating (stimulation or inhibition) certain brain areas could be a promising new intervention for substance abuse and to reduce violent behavior, such as the neurostimulation technique Transcranial Direct Current Stimulation (tDCS). This study aims to investigate tDCS as an intervention to increase empathic abilities and reduce violent behavior in forensic substance use offenders. Methods/design A total sample of 50 male forensic substance abuse patients (25 active + 25 sham stimulation) will be tested in a double-blind placebo-controlled study, from which half of the patients will receive an active stimulation + treatment as usual (TAU) and the other half will receive a sham stimulation (placebo) + TAU. The patients in the active condition will receive multichannel tDCS stimulation targeting bilateral vmPFC two times a day for 20 minutes for five consecutive days. Before and after the stimulation period, the patients will complete self-report measurements, perform the Point Subtraction Aggression Paradigm (PSAP) and a passive viewing empathy task. Resting state electroencephalography (rsEEG) will be measured before and after the treatment period. A follow-up will be conducted after six months. Primary outcome is to investigate multichannel tDCS as a new intervention to increase empathic abilities and wit that reduce violent behavior in offenders with substance abuse problems. In addition, it will be studied whether electrophysiological responses in the brain are affected by the tDCS intervention. Lastly the effects of tDCS on reducing craving will be investigated. Discussion This study is one of the first studies using multichannel tDCS targeting the vmPFC in a forensic sample. This study will explore the opportunities to introduce a new intervention to improve empathic abilities and reduce violence in forensic substance use offenders. Specifically, this study may give insight in how to implement the tDCS intervention in the setting of daily clinical practice for this complex, multiple problem target group and with that contribute to reduction of recidivism. Trial registration Dutch Trial Register, identifier: NTR7701. Registered on 12 January 2019; prospectively registered before the recruitment phase. Recruitment started on the 1st of February 2019 and approximitaly will be finished in the winter of 2019. https://www.trialregister.nl/trial/7459.| Protcol version 1. 22th of May 2019.

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“…Aggression is stated here as behavior that is mostly defined by any behavior that is intended to harm someone who is motivated to avoid being harmed [17]. As said before, antisocial behavior, especially aggression, is associated with dysfunctions in the prefrontal cortex [18][19][20][21][22][23][24]. In addition, research has highlighted the importance of executive functions; the 'higher' cognitive functions that are controlled by the prefrontal cortex in control of aggression [25][26][27][28].…”

Section: Introductionmentioning

confidence: 99%

Transcranial Direct Current Stimulation (tDCS) as an intervention to improve empathic abilities and reduce violent behavior in forensic offenders: study protocol for a randomized controlled trail.

Sergiou

Woods

Franken

et al. 2019

Preprint

View full text Add to dashboard Cite

Background Recent studies show that changes in one of the brain areas related to empathic abilities (i.e. the Ventromedial Prefrontal Cortex (vmPFC)) plays an important role in violent behavior in abusers of alcohol and cocaine. According to the models of James Blair, empathy is a potential inhibitor of violent behavior. Individuals with less empathic abilities may be less susceptible and motivated to inhibit violent behavior, which causes a higher risk of violence. Recent neuroscientific research shows that modulating (stimulation or inhibition) certain brain areas could be a promising new intervention for substance abuse and to reduce violent behavior, such as the neurostimulation technique Transcranial Direct Current Stimulation (tDCS). This study aims to investigate tDCS as an intervention to increase empathic abilities and reduce violent behavior in forensic substance use offenders. Methods/design A total sample of 50 male forensic substance abuse patients (25 active + 25 sham stimulation) will be tested in a double-blind placebo-controlled study, from which half of the patients will receive an active stimulation + treatment as usual (TAU) and the other half will receive a sham stimulation (placebo) + TAU. The patients in the active condition will receive multichannel tDCS stimulation targeting bilateral vmPFC two times a day for 20 minutes for five consecutive days. Before and after the stimulation period, the patients will complete self-report measurements, perform the Point Subtraction Aggression Paradigm (PSAP) and a passive viewing empathy task. Resting state electroencephalography (rsEEG) will be measured before and after the treatment period. A follow-up will be conducted after six months. Primary outcome is to investigate multichannel tDCS as a new intervention to increase empathic abilities and wit that reduce violent behavior in offenders with substance abuse problems. In addition, it will be studied whether electrophysiological responses in the brain are affected by the tDCS intervention. Lastly the effects of tDCS on reducing craving will be investigated. Discussion This study protocol describes the design of an intervention using multichannel tDCS targeting the vmPFC. This study will explore the opportunities to introduce a new intervention to improve empathic abilities and reduce violence in forensic substance use offenders. In addition, this study may help to reduce craving. The study will contribute to knowledge about increasing empathic abilities and the functioning of the vmPFC. Specifically, this study may give insight in how to implement the tDCS intervention in the setting of daily clinical practice for this complex, multiple problem target group and with that contribute to reduction of recidivism. Trial registration Dutch Trial Register, identifier: NTR7701. Registered on 12 January 2019; prospectively registered before the recruitment phase. https://www.trialregister.nl/trial/7459

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QEEG and LORETA in Teenagers With Conduct Disorder and Psychopathic Traits

Cited by 15 publications

References 89 publications

A Pilot Study on the Effects of Transcranial Direct Current Stimulation on Brain Rhythms and Entropy during Self-Paced Finger Movement using the Epoc Helmet

A Pilot Study on the Effects of Transcranial Direct Current Stimulation on Brain Rhythms and Entropy during Self-Paced Finger Movement using the Epoc Helmet

Transcranial Direct Current Stimulation (tDCS) as an intervention to improve empathic abilities and reduce violent behavior in forensic offenders: Study protocol for a randomized controlled trial.

Transcranial Direct Current Stimulation (tDCS) as an intervention to improve empathic abilities and reduce violent behavior in forensic offenders: study protocol for a randomized controlled trail.

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