qSOFA is a useful prognostic factor for 30-day mortality in infected patients fulfilling the SIRS criteria for sepsis

Abdullah, S M Osama Bin; Grand, Johannes; Sijapati, Astha; Puri, Pushpa Raj; Nielsen, Finn Erland

doi:10.1016/j.ajem.2019.05.037

Cited by 15 publications

(12 citation statements)

References 32 publications

(60 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Though SIRS score is inferior to qSOFA score for the prediction of adverse outcome in our results, it adds the advantage of predictive value together with age and /or other parameters compared with the simpler qSOFA score. A recent study suggested that at least 2 of qSOFA score could be an alternative parameter for septic patients fulfilled the SIRS criteria [10]. In our results we show that qSOFA score of more than zero can predict adverse outcome of SFTS with high sensitivity which indicates that qSOFA score as a synthetical index can be used as a sensitive indicator for predicting prognosis of SFTS.…”

Section: Discussionsupporting

confidence: 63%

Predictive risk score model for severe fever with thrombocytopenia syndrome mortality based on qSOFA and SIRS scoring system

Wang

Ding

Hou

et al. 2019

Preprint

View full text Add to dashboard Cite

Background: Severe fever with thrombocytopenia syndrome (SFTS) is a severe systemic virus infectious disease usually having multi-organ dysfunction which resembles sepsis.Methods: A total of 321 patients with laboratory-confirmed SFTS from May 2013 to July 2017 were retrospectively analysed. Demographic and clinical characteristics, calculated quick sequential organ failure assessment (qSOFA) score and systemic inflammatory response syndrome (SIRS) criteria for survivors and nonsurvivors were compared. Independent risk factors associated with in-hospital mortality were obtained using multivariable logistic regression analysis. Risk score models containing different risk factors for mortality in stratified patients were established whose predictive values were evaluated using area under ROC curve (AUC).Results: Of 321 patients, 87 died (27.1%). Age (p<0.001) and percentage numbers of patients with qSOFA≥2 and SIRS≥2 (p<0.0001) were profoundly greater in nonsurvivors than in survivors. Age, qSOFA, SIRS score and aspartate aminotransferase (AST) were independent risk factors for mortality for all patients. And qSOFA score was the only common risk factor in all patients, those of age≥60 years and those enrolled in intensive care unit (ICU). A risk score model containing all these risk factors (Model1) has high predictive value for in-hospital mortality in these three groups with AUCs (95% CI): 0.919 (0.883-0.946), 0.929 (0.862-0.944) and 0.815 (0.710-0.894), respectively. Kaplan-Meier survival analysis showed a strong difference between high-risk and low-risk groups at a cutoff value > 9.22 (log-rank c2 = 126.3, p <0.0001) Conclusions: qSOFA and risk models containing qSOFA have high predictive validity for SFTS in-hospital mortality.

show abstract

Section: Discussionsupporting

confidence: 63%

Predictive risk score model for severe fever with thrombocytopenia syndrome mortality based on qSOFA and SIRS scoring system

Wang

Ding

Hou

et al. 2019

Preprint

View full text Add to dashboard Cite

show abstract

“…Though SIRS score is inferior to qSOFA score for the prediction of adverse outcome in our results, it adds the advantage of predictive value together with age and /or other parameters compared with the simpler qSOFA score. A recent study suggested that at least 2 of qSOFA score could be an alternative parameter for septic patients fulfilled the SIRS criteria [11]. In our results we show that qSOFA score of more than zero can predict adverse outcome of SFTS with high sensitivity which indicates that qSOFA score as a synthetical index can be used combining with age or used solely as a sensitive indicator for predicting prognosis of SFTS.…”

Section: Discussionsupporting

confidence: 61%

Predictive risk score model for severe fever with thrombocytopenia syndrome mortality based on qSOFA and SIRS scoring system

et al. 2020

View full text Add to dashboard Cite

Background: Severe fever with thrombocytopenia syndrome (SFTS) is a severe systemic virus infectious disease usually having multi-organ dysfunction which resembles sepsis. Methods: Data of 321 patients with laboratory-confirmed SFTS from May 2013 to July 2017 were retrospectively analyzed. Demographic and clinical characteristics, calculated quick sequential organ failure assessment (qSOFA) score and systemic inflammatory response syndrome (SIRS) criteria for survivors and nonsurvivors were compared. Independent risk factors associated with in-hospital mortality were obtained using multivariable logistic regression analysis. Risk score models containing different risk factors for mortality in stratified patients were established whose predictive values were evaluated using the area under ROC curve (AUC). Results: Of 321 patients, 87 died (27.1%). Age (p < 0.001) and percentage numbers of patients with qSOFA≥2 and SIRS≥2 (p < 0.0001) were profoundly greater in nonsurvivors than in survivors. Age, qSOFA score, SIRS score and aspartate aminotransferase (AST) were independent risk factors for mortality for all patients. qSOFA score was the only common risk factor in all patients, those age ≥ 60 years and those enrolled in the intensive care unit (ICU). A risk score model containing all these risk factors (Model1) has high predictive value for in-hospital mortality in these three groups with AUCs (95% CI): 0.919 (0.883-0.946), 0.929 (0.862-0.944) and 0.815 (0.710-0.894), respectively. A model only including age and qSOFA also has high predictive value for mortality in these groups with AUCs (95%

show abstract

“…Though SIRS score is inferior to qSOFA score for the prediction of adverse outcome in our results, it adds the advantage of predictive value together with age and /or other parameters compared with the simpler qSOFA score. A recent study suggested that at least 2 of qSOFA score could be an alternative parameter for septic patients ful lled the SIRS criteria [11]. In our results we show that qSOFA score of more than zero can predict adverse outcome of SFTS with high sensitivity which indicates that qSOFA score as a synthetical index can be used combining with age or used solely as a sensitive indicator for predicting prognosis of SFTS.…”

Section: Discussionsupporting

confidence: 60%

Predictive risk score model for severe fever with thrombocytopenia syndrome mortality based on qSOFA and SIRS scoring system

Wang

Zou²,

Ding

et al. 2020

Preprint

View full text Add to dashboard Cite

Abstract Background: Severe fever with thrombocytopenia syndrome (SFTS) is a severe systemic virus infectious disease usually having multi-organ dysfunction which resembles sepsis.Methods: Data of 321 patients with laboratory-confirmed SFTS from May 2013 to July 2017 were retrospectively analyzed. Demographic and clinical characteristics, calculated quick sequential organ failure assessment (qSOFA) score and systemic inflammatory response syndrome (SIRS) criteria for survivors and nonsurvivors were compared. Independent risk factors associated with in-hospital mortality were obtained using multivariable logistic regression analysis. Risk score models containing different risk factors for mortality in stratified patients were established whose predictive values were evaluated using the area under ROC curve (AUC).Results: Of 321 patients, 87 died (27.1%). Age (p<0.001) and percentage numbers of patients with qSOFA≥2 and SIRS≥2 (p<0.0001) were profoundly greater in nonsurvivors than in survivors. Age, qSOFA, SIRS score and aspartate aminotransferase (AST) were independent risk factors for mortality for all patients. And qSOFA score was the only common risk factor in all patients, those age≥60 years and those enrolled in the intensive care unit (ICU). A risk score model containing all these risk factors (Model1) has high predictive value for in-hospital mortality in these three groups with AUCs (95% CI): 0.919 (0.883-0.946), 0.929 (0.862-0.944) and 0.815 (0.710-0.894), respectively. A model only including age and qSOFA also has high predictive value for mortality in these groups with AUCs (95% CI): 0.872 (0.830-0.906), 0.885(0.801-0.900) and 0.865 (0.767-0.932), respectively.Conclusions: Risk models containing qSOFA have high predictive validity for SFTS mortality.

show abstract

qSOFA is a useful prognostic factor for 30-day mortality in infected patients fulfilling the SIRS criteria for sepsis

Cited by 15 publications

References 32 publications

Predictive risk score model for severe fever with thrombocytopenia syndrome mortality based on qSOFA and SIRS scoring system

Predictive risk score model for severe fever with thrombocytopenia syndrome mortality based on qSOFA and SIRS scoring system

Predictive risk score model for severe fever with thrombocytopenia syndrome mortality based on qSOFA and SIRS scoring system

Predictive risk score model for severe fever with thrombocytopenia syndrome mortality based on qSOFA and SIRS scoring system

Contact Info

Product

Resources

About