QT interval dispersion pattern in patients with acute ischemic stroke: Does the site of infarction matter?

Alabd, Ali A; Fouad, Amal; Abdel-Nasser, Reda; Nammas, Wail

doi:10.1055/s-0031-1278349

Cited by 10 publications

(16 citation statements)

References 20 publications

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“…QTd of stroke patients was compared to QTd of a non-stroke control group in 9 studies (25–27,29–32,37,38). Five included hemorrhagic stroke patients exclusively, and 2 included only ischemic stroke patients.…”

Section: Resultsmentioning

confidence: 99%

“…Serial QTd measurements were recorded in 6 studies (25,26 29,31,32,36). Four out of 6 studies measured QTd twice (25,29,32,36) and 2 out of 6 studies performed QTd measurements daily (26,31): Golbasi et al evaluated QTd continuously for 5 days, and Randell et al evaluated QTd for 9 days. One additional study (34) compared pre-stroke and post-stroke QTd.…”

Section: Resultsmentioning

confidence: 99%

“…Some of the stroke risk factors considered included diabetes mellitus and hypertension. Patients with diabetes mellitus were excluded in one study (29) and controlled for in 7 studies (22,28,32,34–36,38) while hypertension was controlled for in 8 studies (22,27,28,32,34–36,38). There was considerable heterogeneity in the methods used to account for different variables including heart disease, electrolyte disturbances and medications known to affect the QT Interval (41,42).…”

Section: Resultsmentioning

confidence: 99%

“…Serial QTd measurements were reported in 6 studies (25,26,29,31,32,36). Three out of 6 (25,29,32) evaluated an admission ECG and found that stroke patients had significantly greater QTd values as compared to non-stroke controls.…”

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Relationship between QT Interval Dispersion in Acute Stroke and Stroke Prognosis: A Systematic Review

Lederman

Balucani

Lazar

et al. 2014

Journal of Stroke and Cerebrovascular Diseases

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Background QT dispersion (QTd) has been proposed as an indirect ECG measure of heterogeneity of ventricular repolarization. The predictive value of QTd in acute stroke remains controversial. We aimed to clarify the relationship between QTd and acute stroke and stroke prognosis. Methods A systematic review of the literature was performed using pre-specified medical subjects heading (MeSH) terms, Boolean logic and the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Eligible studies (a) included ischemic or hemorrhagic stroke and (b) provided QTd measurements. Results Two independent reviewers identified 553 publications. Sixteen articles were included in the final analysis. There were a total of 888 stroke patients: 59% ischemic and 41% hemorrhagic. There was considerable heterogeneity in study design, stroke subtypes, ECG assessment-time, control groups and comparison groups. Nine studies reported a significant association between acute stroke and baseline QTd. Two studies reported that QTd increases are specifically related to hemorrhagic strokes, involvement of the insular cortex, right-side lesions, larger strokes, and increases in 3, 4-dihydroxyphenylethylene glycol in hemorrhagic stroke. Three studies reported QTd to be an independent predictor of stroke mortality. One study each reported increases in QTd in stroke patients who developed ventricular arrhythmias and cardiorespiratory compromise. Conclusions There are few well-designed studies and considerable variability in study design in addressing the significance of QTd in acute stroke. Available data suggest that stroke is likely to be associated with increased QTd. While some evidence suggests a possible prognostic role of QTd in stroke, larger and well-designed studies need to confirm these findings.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Relationship between QT Interval Dispersion in Acute Stroke and Stroke Prognosis: A Systematic Review

Lederman

Balucani

Lazar

et al. 2014

Journal of Stroke and Cerebrovascular Diseases

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“…Данные литературы о дисперсии интервала QT при инсульте неод-нозначны. На увеличение дисперсии QT, связанной с повреждени-ем миокарда у пациентов с инсультом указывают несколько авторов [167,175,219], тогда как в другой работе [234], повышения дисперсии QT не было выявлено.…”

Section: интервал Qtunclassified

Препараты Метаболического Действия В Комплексной Терапии Цереброкардиального Синдрома При Ишемическом Инсульте

Прекина¹,

Самолькина²

2014

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QT dispersion in mild cognitive impairment: a possible tool for predicting the risk of progression to dementia?

Coppola

Mastrolorenzo

Coppola

et al. 2012

Int J Geriat Psychiatry

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QT interval dispersion pattern in patients with acute ischemic stroke: Does the site of infarction matter?

Cited by 10 publications

References 20 publications

Relationship between QT Interval Dispersion in Acute Stroke and Stroke Prognosis: A Systematic Review

Relationship between QT Interval Dispersion in Acute Stroke and Stroke Prognosis: A Systematic Review

Препараты Метаболического Действия В Комплексной Терапии Цереброкардиального Синдрома При Ишемическом Инсульте

QT dispersion in mild cognitive impairment: a possible tool for predicting the risk of progression to dementia?

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