Quadriceps strengthening exercises may not change pain and function in knee osteoarthritis

Bokaeian, Hamid Reza; Bakhtiary, Amir Hoshang; Mirmohammadkhani, Majid; Moghimi, Jamileh

doi:10.1016/j.jbmt.2017.06.013

Cited by 19 publications

(20 citation statements)

References 43 publications

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“…This finding was demonstrated by the significant association (ρ = 0.78; p = 0.02) between the percentage of outlier gait cycles observed in post-intervention gait and clinical outcome improvement. In the context of previous univariate models examining the association of changes in muscle strength (r 2 = 0.28–0.31; [ 37 ]) or pain sensitization (ρ = 0.28–0.35; [ 38 ]) to changes in self-reported outcomes in knee OA patients following exercise, the current association is comparatively large. To our knowledge, this is the first study to integrate pattern recognition algorithms with wearable technology to define objective, subject-specific biomechanical outcomes related to clinical improvements.…”

Section: Discussionmentioning

confidence: 69%

Wearable Sensor Data to Track Subject-Specific Movement Patterns Related to Clinical Outcomes Using a Machine Learning Approach

Kobsar

Ferber

2018

Sensors

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Wearable sensors can provide detailed information on human movement but the clinical impact of this information remains limited. We propose a machine learning approach, using wearable sensor data, to identify subject-specific changes in gait patterns related to improvements in clinical outcomes. Eight patients with knee osteoarthritis (OA) completed two gait trials before and one following an exercise intervention. Wearable sensor data (e.g., 3-dimensional (3D) linear accelerations) were collected from a sensor located near the lower back, lateral thigh and lateral shank during level treadmill walking at a preferred speed. Wearable sensor data from the 2 pre-intervention gait trials were used to define each individual’s typical movement pattern using a one-class support vector machine (OCSVM). The percentage of strides defined as outliers, based on the pre-intervention gait data and the OCSVM, were used to define the overall change in an individual’s movement pattern. The correlation between the change in movement patterns following the intervention (i.e., percentage of outliers) and improvement in self-reported clinical outcomes (e.g., pain and function) was assessed using a Spearman rank correlation. The number of outliers observed post-intervention exhibited a large association (ρ = 0.78) with improvements in self-reported clinical outcomes. These findings demonstrate a proof-of-concept and a novel methodological approach for integrating machine learning and wearable sensor data. This approach provides an objective and evidence-informed way to understand clinically important changes in human movement patterns in response to exercise therapy.

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Section: Discussionmentioning

confidence: 69%

Wearable Sensor Data to Track Subject-Specific Movement Patterns Related to Clinical Outcomes Using a Machine Learning Approach

Kobsar

Ferber

2018

Sensors

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“…The present study suggests that VM (RMS) positively influences the balance ability. Changes in the quadriceps' muscle strength, decreased proprioception and increased postural sway were noticed in the patients in the knee OA group [11], and quadriceps strengthening is widely used during osteoarthritis physiotherapy management [20,21]. However, it should be analysed whether early changes in the muscle strength in the VM [21] due to pain are associated with changes in the balance ability of patients with knee osteoarthritis.…”

Section: Discussionmentioning

confidence: 99%

Analysis of the Relationships between Balance Ability and Walking in Terms of Muscle Activities and Lower Limb Kinematics and Kinetics

et al. 2021

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There is a lack of evidence about the ways in which balance ability influences the kinematic and kinetic parameters and muscle activities during gait among healthy individuals. The hypothesis is that balance ability would be associated with the lower limb kinematics, kinetics and muscle activities during gait. Twenty-nine healthy volunteers (Age 32.8 ± 9.1; 18 males and 11 females) performed a Star Excursion Balance test to measure their dynamic balance and walked for at least three trials in order to obtain a good quality of data. A Vicon® 3D motion capture system and AMTI® force plates were used for the collection of the movement data. The selected muscle activities were recorded using Delsys® Electromyography (EMG). The EMG activities were compared using the maximum values and root mean squared (RMS) values within the participants. The joint angle, moment, force and power were calculated using a Vicon Plug-in-Gait model. Descriptive analysis, correlation analysis and multivariate linear regression analysis were performed using SPSS version 23. In the muscle activities, positive linear correlations were found between the walking and balance test in all muscles, e.g., in the multifidus (RMS) (r = 0.800 p < 0.0001), vastus lateralis (RMS) (r = 0.639, p < 0.0001) and tibialis anterior (RMS) (r = 0.539, p < 0.0001). The regression analysis models showed that there was a strong association between balance ability (i.e., reaching distance) and the lower limb muscle activities (i.e., vastus medialis–RMS) (R = 0.885, p < 0.0001), and also between balance ability (i.e., reaching distance) and the lower limb kinematics and kinetics during gait (R = 0.906, p < 0.0001). In conclusion, the results showed that vastus medialis (RMS) muscle activity mainly contributes to balance ability, and that balance ability influences the lower limb kinetics and kinematics during gait.

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“…In addition, IL-1β and TNF-α contribute to NF-kB activation in synovial cells and chondrocytes, both commonly implicated in OA pathogenesis (19). Another important factor that can be attributed to pain improvement after exercise is the facilitation of endorphin release, which makes the patient more tolerant to it (20,21). The effectiveness of therapeutic ground exercise for people with knee and hip OA has been investigated in terms of pain reduction and disability (22).…”

Section: Discussionmentioning

confidence: 99%

Associated Strengthening Exercises to Undenatured Oral Type II Collagen UCII. A Randomized Study in Patients Affected by Knee Osteoarthritis

Costa

Teixeira²,

Pereira³

et al. 2020

Muscle Ligaments and Tendons J

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Background. Osteoarthritis (OA) is a chronic joint disease characterized by progressive degeneration of articular cartilage. It affects 20-25% of the population older than 45 years. The objective was to evaluate the effect of combining muscle strengthening exercises with the administration of oral type II undenatured collagen formulation (UC-II) in people with knee OA. Methods. A double-blind, placebo-controlled, randomized controlled trial with 60 patients with knee OA, randomly divided into the following groups: UC-II and physiotherapy group (CPG), placebo UC-II and physiotherapy group (PCPG), and physiotherapy group (PG). For groups using an oral type II undenatured collagen formulation, UC-II, 40 mg/day UC-II was administered for 90 days. Muscle strengthening exercises were associated with neuromuscular electrical stimulation (NMES), being performed three times a week for 30 days. At 30 and 90 days and six months after the intervention, the following were evaluated: pain, quality of life, functional capacity, muscle strength, and joint mobility. Results. Pain improved in all intervention groups, with no difference between groups. Quadriceps muscle strength increased in the CPG (p<0.005) and PG (p<0.05), the same being observed for active and passive knee flexion mobility (p<0.05). All groups decreased the TUG test execution time after 30 days (p<0.005 for the CPG and PG, and p<0.05 for the PCPG), but only the CPG and PG maintained the scores at 90-day and six-month assessments (p<0.005). Regarding the 6MWT, only the CPG increased the distance covered in all assessments (p<0.005). The PG traveled a greater distance than the PCPG at the 90-day assessment (p<0.05). The WOMAC score decreased significantly in all intervention groups. The Lequesne score decreased in all groups; however, the CPG and PG showed lower values at 30 days (p<0.005). Conclusions. Muscle strengthening exercises improved pain, mobility, strength, and function in knee OA patients. The association of UC-II seems to have accentuated the effect of exercise on this clinical improvement, especially in the long term.

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Quadriceps strengthening exercises may not change pain and function in knee osteoarthritis

Cited by 19 publications

References 43 publications

Wearable Sensor Data to Track Subject-Specific Movement Patterns Related to Clinical Outcomes Using a Machine Learning Approach

Wearable Sensor Data to Track Subject-Specific Movement Patterns Related to Clinical Outcomes Using a Machine Learning Approach

Analysis of the Relationships between Balance Ability and Walking in Terms of Muscle Activities and Lower Limb Kinematics and Kinetics

Associated Strengthening Exercises to Undenatured Oral Type II Collagen UCII. A Randomized Study in Patients Affected by Knee Osteoarthritis

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