Qualitative analysis of dental material ingredients, composite resins and sealants using liquid chromatography coupled to quadrupole time of flight mass spectrometry

Vervliet, Philippe; Nys, Siemon De; Boonen, Imke; Duca, Radu Corneliu; Elskens, Marc; Landuyt, Kirsten Van

doi:10.1016/j.chroma.2018.09.039

Cited by 35 publications

(32 citation statements)

References 45 publications

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“…Thus, Bis‐EMA oligomers seem to have the same CAS number, as also reported by Vervilet et al . . From a health, safety, and environmental perspective, molecular weight (or M n ) should accompany CAS numbers in the safety data sheet, so that dentists can find the content of the material they are using and for which they are responsible.…”

Section: Discussionmentioning

confidence: 99%

Airborne exposure to gaseous and particle‐associated organic substances in resin‐based dental materials during restorative procedures

Nilsen

Jensen

Örtengren

et al. 2019

European J Oral Sciences

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Dental composite dust has been shown to act as a vehicle for methacrylates in vivo/in vitro. The objective of this study was to assess airborne exposure of dental personnel to gaseous and particle‐associated organic constituents from resin‐based dental materials in a simulated clinic. Sampling of total aerosol fractions and gaseous substances was performed by dental students carrying particle filters and gas sorbents attached to a personal pump during preclinical restorative procedures in phantom models (n = 13). Water from the phantoms was sampled. Organic substances were extracted from the sampled water, particle filters, and gas sorbents. Qualitative and quantitative analyses were performed by gas chromatography‐mass spectrometry (GC‐MS) and ultra‐high‐performance liquid chromatography‐mass spectrometry (UHPLC‐MS). The methacrylates 2‐hydroxyethyl methacrylate (HEMA) and triethylene glycol dimethacrylate (TEGDMA) and the additives camphorquinone (CQ), butylated hydroxytoluene (BHT), and ethyl 4‐(dimethylamino)benzoate (DMABEE), were quantified in the gas and particle fractions sampled. A positive‐control experiment was conducted. No methacrylates were detected in the gas or particle fractions sampled, whereas strong signals for methacrylates were detected in the positive controls, matching the analysis of the uncured material. In addition, TEGDMA and DMABEE were quantified in the sampled water. Airborne exposure to constituents in resin‐based dental materials was below the detection limit. However, the extent of exposure is probably dependent on the procedure, preventive measures, and type of materials used.

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Section: Discussionmentioning

confidence: 99%

Airborne exposure to gaseous and particle‐associated organic substances in resin‐based dental materials during restorative procedures

Nilsen

Jensen

Örtengren

et al. 2019

European J Oral Sciences

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“…27). Клинический случай / Clinical cases ОБСУЖДЕНИЕ Композитные материалы для устранения дисколоритов, существующие в настоящее время на стоматологическом рынке, являются высокоэффективными и относительно дешевыми [5]. Их использование возможно в широком спектре реставрационных возможностей -от покрытия реставраций на основе титана, облицованного композитом, до покрытия металлических штифтов для перекрытия синего цвета, и также до перекрытия поверхности измененных в цвете тканей зуба после эндодонтического лечения и даже покрытия синего оттенка под реставрациями, граничащими с хорошо видимым эмалированно-дентиновым соединением.…”

Section: клинический случайunclassified

“…Другими проблемами, с которыми мы можем столкнуться при планировании реставрационного лечения, являются степень обесцвечивания дентина, оценка возможности внутреннего отбеливания [3], без неоправданного увеличения риска цервикальной резорбции, выбор техники -прямое или непрямое эстетическое восстановление зубов [4], и, наконец, подробный анализ цвета и фотодинамики материала [5], особенно в контексте асимметричной работы.…”

Section: Introductionunclassified

Management of discolored tissues after endodontic treatment in direct composite reconstructions

Pisuk

2020

Èndodontiâ today

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Internal tooth discoloration is a problem in aesthetic restorations in the anterior maxilla, which requires analysis of many causative factors, assessment of restoration possibilities, as well as aesthetics of soft tissues, including the position of the lips with regards to a smile and the often encountered blue gum zenith. This article presents a clinical case in which an aesthetic direct restoration of the maxillary incisors was performed as an alternative to prosthodontic treatment after drawing up a treatment plan and determining indications.

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“…Bisphenol A (BPA) is a chemical widely used in the manufacture of polycarbonate plastics and epoxy resins, with more than 6 billion pounds produced each year. It is present in many consumer products, such as food containers (Lorber et al, 2015), water bottles (Rowell, Kuiper, & Preud'Homme, 2016), thermal receipts (Sogorb, Estévez, & Vilanova, 2019), and dental sealants (Vervliet et al, 2018). Due to the high quantity of BPA in industrial products, human exposure to BPA is essentially ubiquitous, mainly through diet (Lakind, & Naiman, 2011; Lorber et al, 2015), inhalation (Alkasir, Rossner, & Andreescu, 2015), and dermal absorption (Toner, Allan, Dimond, Waechter, & Beyer, 2018).…”

Section: Introductionmentioning

confidence: 99%

Neonatal exposure to bisphenol A advances pubertal development in female rats

Qiu

Sun

et al. 2020

Molecular Reproduction Devel

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Neonatal exposure to bisphenol A (BPA) is hypothesized to advance pubertal development. However, the effects of neonatal BPA exposure on pubertal development has not been described. In this study, female Sprague-Dawley rats were exposed to 0.05, 0.5, 5, or 10 mg·kg −1 ·day −1 BPA, or corn oil vehicle alone from postnatal day 1 (PND1) to PND10 via subcutaneous injection. We evaluated day of vaginal opening (DVO), ovarian morphology, serum hormone concentrations, and hypothalamic expression of Gnrh1 and Kiss1 in female rats at PND35. DVO was significantly advanced in rats exposed to 5 and 10 mg·kg −1 ·day −1 BPA. Serum hormone concentrations increased as BPA dose increased. Additionally, hypothalamic Gnrh1 and Kiss1 expression were increased with BPA exposure; rats exposed to 10 mg·kg −1 ·day −1 BPA had significantly upregulated hypothalamic Gnrh1 and Kiss1 expressions in terms of both messenger RNA and protein levels. Our results suggest that exposure to a 10 mg·kg −1 ·day −1 dose of BPA might advance pubertal development significantly. In addition, within the range of 0 to 10 mg·kg −1 ·day −1 , neonatal exposure to BPA may affect pubertal development in a dose-dependent manner.

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Qualitative analysis of dental material ingredients, composite resins and sealants using liquid chromatography coupled to quadrupole time of flight mass spectrometry

Cited by 35 publications

References 45 publications

Airborne exposure to gaseous and particle‐associated organic substances in resin‐based dental materials during restorative procedures

Airborne exposure to gaseous and particle‐associated organic substances in resin‐based dental materials during restorative procedures

Management of discolored tissues after endodontic treatment in direct composite reconstructions

Neonatal exposure to bisphenol A advances pubertal development in female rats

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