Qualitative analysis of HIV and AIDS disease transmission: impact of awareness, testing and effective follow up

Abstract

Background: Since the early 1980s, human immunodeficiency virus (HIV) and its accompanying acquired immunodeficiency syndrome (AIDS) have spread worldwide, becoming one of the world's major global health issues. From the beginning of the epidemic until 2020, about 79.3 million people became infected, with 36.3 million deaths due to AIDS illnesses. This huge figure is a result of those unaware of their status due to stigmatization and invariably spreading the virus unknowingly. Methods: Qualitative analysis through a mathematical model that will address HIV unaware individuals and the effect of an increasing defaulter on the dynamics of HIV/AIDS was investigated. The impact of treatment and the effect of inefficient follow-up on the transmission of HIV/AIDS were examined. The threshold for the effective reduction of the unaware status of HIV through testing, in response to awareness, and the significance of effective non-defaulting in treatment commonly called defaulters loss to follow-up as these individuals contribute immensely to the spread of the virus due to their increase in CD4+ count was determined in this study. Stability analysis of equilibrium points is performed using the basic reproduction number $R_0$, an epidemiological threshold that determines disease eradication or persistence in viral populations. We tested the most sensitive parameters in the basic reproduction numbers. The model of consideration in this study is based on the assumption that information (awareness) and non-stigmatization can stimulate change in the behaviours of infected individuals, and can lead to an increase in testing and adherence to treatment. This will in turn reduce the basic reproduction number, and consequently, the spread of the virus. Results: The results portray that the early identification and treatment are inadequate for the illness to be eradicated. Conclusions: Other control techniques, such as treatment adherence and effective condom usage, should be investigated in order to lessen the disease's burden.

Navigating the Crossroads: Sexual Attitudes, HIV Awareness, and the Need for Targeted Education Among College Students in Southeast Coast China.

“…Regarding the relationship between HIV/AIDS-related knowledge and health education towards HIV/AIDS, college students who receive more comprehensive education on HIV have a stronger understanding of the virus, in line with previous research [6, 30,34,41]. This group of students demonstrates greater caution and resistance to engaging in risky sexual behavior [6, [23][24][25], resulting in lower HIV incidence compared to those with limited HIV knowledge [22,26]. Therefore, increasing the extent and scope of AIDS-related education in colleges is of signi cant importance in preventing and controlling HIV/AIDS.…”

“…This cross-sectional study aims to present an analysis of the present-day awareness of HIV/AIDS among college students with conservative and open sexual attitudes in Wenzhou city. HIV/AIDS-related knowledge plays a signi cant role in preventing and controlling HIV [22]. Lack of knowledge about HIV is associated with increased frequency of risky sexual behaviors and self-infection risk [6, [23][24][25], leading to greater susceptibility and transmission of AIDS [22,26].…”

“…HIV/AIDS-related knowledge plays a signi cant role in preventing and controlling HIV [22]. Lack of knowledge about HIV is associated with increased frequency of risky sexual behaviors and self-infection risk [6, [23][24][25], leading to greater susceptibility and transmission of AIDS [22,26]. Our study revealed that the overall awareness rate of HIV was 80.3% and we noted the following differences according to sexual attitudes group: HIV awareness rates were 80.3% and 80.1% among the students with conservative sexual attitudes and students with open sexual attitudes.…”

“…Sexual health education has been shown to increase students' knowledge about AIDS [9], reduce the prevalence of AIDS [22,26], and increase their willingness to get tested [42]. Additionally, it may be effective in reducing discrimination against AIDS patients [43].…”

Bending the Curve Through Innovations to Overcome Persistent Obstacles in HIV Prevention and Treatment

“…The virus progressively impairs the immune system by attacking and destroying CD4 T cells, resulting in life-threatening opportunistic infections [5]. Without treatment, most HIV-infected individuals will develop AIDS in an average of 8-10 years after initial infection [6].…”