Qualitative and quantitative comparison of hormone contents between bovine and human colostrums

Xu, Li; Zhang, Lanwei; Zhang, Yumei; Qing-hai, Sheng; Zhao, Aihua

doi:10.1016/j.idairyj.2010.04.006

Cited by 16 publications

(12 citation statements)

References 33 publications

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“…The rest of the samples had lower levels of P 4 . The estrone levels observed in the milk analyzed in this study were also variable, showing concentrations in the range of human colostrum and mature milk [19,20], or even higher than one-day colostrum in two cases. It is, nevertheless, important to note that human colostrum may present higher values of these natural hormones.…”

Section: Resultsmentioning

confidence: 92%

“…To date, very few studies have reported the levels of these natural compounds in formulas and human breast milk. Moreover, in most cases the data in the literature is limited to estrone (E 1 ) and/or estradiol (E 2 ) [15,16,18,19,20]. In this study, six naturally occurring steroid hormones have been determined and quantified in milk and milk formulas intended for babies and children.…”

Section: Resultsmentioning

confidence: 99%

“…), using different analytical methods (HPLC-MS/MS, immunoassays) [6,9,19,20,26,28,29,30,31]. So far, there has been limited research on the hormonal levels of infant formulas prepared using bovine milk [15,19] or on the hormone content of human milk [18,19,20]. Some of the data obtained in this study and a summary of the results found in the literature have been included in Table 2, in order to facilitate comparisons between different formulas and various types of milk (human, bovine, commercial).…”

Section: Resultsmentioning

confidence: 99%

“…Dairy preparations for infants and children can be considered an important source of natural hormones, even though the existing information about their concentration in these products is very limited [14,15,16,17]. Therefore, more of these hormonal compounds should be quantified in different types of products to obtain an estimation of their consumption and to compare them with the levels found in human breast milk [18,19,20]. …”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Analysis of Naturally Occurring Steroid Hormones in Infant Formulas by HPLC-MS/MS and Contribution to Dietary Intake

Barreiro

Regal

Díaz-Bao

et al. 2015

Foods

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Milk is a natural fluid and as such contains small amounts of naturally occurring steroids. Human milk is recommended as the optimal source of nutrients for infants and young children, and it has been associated to several short- and long-term benefits. For this reason, its composition is used as a reference for designing infant formulas. However, the available information on the hormonal levels of these dairy products is scarce, and it is usually limited to estradiol and estrone. In the present study, six natural sex hormones (pregnenolone, progesterone, estrone, dehydroepiandrosterone, testosterone and androstenedione) have been extracted from sixteen milk-based infant formulas and analyzed with liquid chromatography tandem mass spectrometry (HPLC-MS/MS). The purpose of this research was to quantify natural steroid hormones in various infant formulas, to provide food and nutrition practitioners with information to estimate intakes in children. In addition, data found in the literature was used for comparison. The findings suggest that there are certain similarities between bovine milk and dairy products for infants. Furthermore, the detected levels were in general lower than those observed in human milk and/or colostrum. The reported results represent a valuable addition to the current knowledge on natural hormone content of infant foods.

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Section: Resultsmentioning

confidence: 92%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Analysis of Naturally Occurring Steroid Hormones in Infant Formulas by HPLC-MS/MS and Contribution to Dietary Intake

Barreiro

Regal

Díaz-Bao

et al. 2015

Foods

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show abstract

“…Estrogens and androgens are mostly analyzed separately [29][30][31][40][41][42][43][44] and a few of studies refer to simultaneous determination of them [27,[45][46][47][48][49]. Our work attempted to simultaneously detect estrogenic and androgenic hormones of different polarities.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous determination of five estrogens and four androgens in water samples by online solid-phase extraction coupled with high-performance liquid chromatography–tandem mass spectrometry

Guo

Liu

et al. 2013

Journal of Chromatography A

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a b s t r a c tA novel method for simultaneous determination of five estrogens and four androgens by online solid-phase extraction (SPE) coupled with high-performance liquid chromatography-tandem mass spectrometry (HPLC-ESI-MS/MS) in water samples was developed. An aliquot of 50 mL water sample after filtration was injected directly into autosampler and the analytes were preconcentrated on a NG1 online SPE column. After cleanup step the analytes were eluted in back flush mode and then separated on a liquid chromatography column. The experimental parameters, such as sample loading flow rate, cleanup condition and elution time, were optimized in detail. Estrogens and androgens were detected in negative and positive mode, respectively. High ionization efficiency of all the analytes was achieved by adding of 1‰ ammonia in the mobile phase. The recoveries ranged from 31.8% to 119.0% and the inter-day RSDs ranged from 2.7% to 19.6%. The limits of detections (LODs) were between 0.1 and 2.5 ng/L. The proposed method was successfully applied to the analysis of three types of water samples, including river water, influent and effluent water from a wastewater treatment plant (WWTP). The recoveries of androgens were not that good and a further study is being planned to improve the sensitivity for them. The proposed method is simple, sensitive and suitable for simultaneous analysis and monitoring of estrogens and androgens in water samples.

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The Fate of Synthetic and Endogenous Hormones Used in the US Beef and Dairy Industries and the Potential for Human Exposure

Kolok

Ali

Rogan³

et al. 2018

Curr Envir Health Rpt

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Bovine somatostatin is detectable in milk; however, there is no evidence that the protein persists in the environment nor that it is active in humans. In contrast, steroids are transported through milk and meat to humans where they may exert biological activity. Furthermore, environmental matrices such as raw water and dust may also allow for the environmental transport and bioavailability of steroids to humans. Endogenous and exogenous steroids can be found in the meat, milk, and waste materials produced by cattle. While the concentrations may be low, exposure to these matrices, most notably dairy products made with whole milk, can be a source of exogenous steroids to humans.

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Qualitative and quantitative comparison of hormone contents between bovine and human colostrums

Cited by 16 publications

References 33 publications

Analysis of Naturally Occurring Steroid Hormones in Infant Formulas by HPLC-MS/MS and Contribution to Dietary Intake

Analysis of Naturally Occurring Steroid Hormones in Infant Formulas by HPLC-MS/MS and Contribution to Dietary Intake

Simultaneous determination of five estrogens and four androgens in water samples by online solid-phase extraction coupled with high-performance liquid chromatography–tandem mass spectrometry

The Fate of Synthetic and Endogenous Hormones Used in the US Beef and Dairy Industries and the Potential for Human Exposure

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