Qualitative evaluation of MRI features in aneurysmal bone cysts after percutaneous sclerotherapy

Bih, Eric S; Dao, Kimberly; Padua, Horacio; Shaikh, Raja

doi:10.1007/s00256-020-03606-6

Cited by 4 publications

(2 citation statements)

References 16 publications

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“…Radiologically, Bih et al [ 10 ▪ ] described decreased cystic areas and improved cortical integrity in over half their cases, on average 5.9 and 10.6 months after initial sclerotherapy. However, paired with increased edema in 19% of cases and presence of fibrosis in 53%.…”

Section: Percutaneous Proceduresmentioning

confidence: 99%

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The treatment of aneurysmal bone cysts

Geloven

Sande²,

Heijden³

2022

Current Opinion in Pediatrics

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Purpose of reviewAneurysmal bone cysts are rare, locally aggressive bone tumors. Optimal treatment of ABCs is still matter of debate as therapies including sclerotherapy, selective arterial embolization and systemic treatment with denosumab are increasingly utilized, in addition to or instead of traditional curettage. The purpose of this review is to discuss current concepts and difficulties in diagnosing and treating primary ABCs, based on latest available literature.Recent findingsIn diagnostics, multiple new fusion partners of USP-6 have been described on next-generation sequencing specifically for primary ABCs. In a recent systematic review, failure rates of percutaneous injections and surgery were comparable. In a literature review, the use of denosumab seemed effective but resulted in multiple cases of severe hypercalcemia in children.SummaryAccurately diagnosing primary ABC is crucial for treatment decisions. Curettage remains a valid treatment option, especially with adjuvant burring, autogenous bone grafting and phenolization. Percutaneous sclerotherapy represents a solid alternative to surgery, with polidocanol showing good results in larger studies. Systematic therapy with denosumab exhibits favorable results but should be reserved in the pediatric population for unresectable lesions, as it may result in severe hypercalcemia in children. When selecting a treatment option, localization, stability and safety should be considered.

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Section: Percutaneous Proceduresmentioning

confidence: 99%

“…On MRI, cystic lesions can be seen, often with fluid–fluid levels, surrounded by fibrous septae and borders with hypointense properties [ 9 ▪ ]. Imaging of these borders and septae can be enhanced with intravenous contrast agent [ 10 ▪ ].…”

Section: Introductionmentioning

confidence: 99%