Quality Analysis of Blood Component (Prbc and Platelet Concentrates): A Study From a Tertiary Care Teaching Hospital of Kumaon Region of Uttarakhand

Upadhyay, Saloni; Pangtey, Tanuja

doi:10.14260/jemds/2016/282

Cited by 2 publications

(2 citation statements)

References 7 publications

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“…An Indian survey analyzed 260 RCC units and reported a mean HCT of 54%, which is less than the hct observed in our study. 10 Another study conducted in Canada analyzed 202 RCC units. The HCT ranged from 59.5% to 64.8%, which is lower than our results.…”

Section: Discussionmentioning

confidence: 99%

Assessment of Internal Quality Control of Blood Products; Experience at a Regional Transfusion Centre from Northern Pakistan

Khan

Tariq

Rathore

et al. 2022

PAFMJ

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Objective: To analyze internal quality control of blood components, including red cell concentrates, fresh frozen plasma, cryoprecipitate and random donor platelets, to measure our blood bank performance. Study Design: Cross-sectional study. Place and Duration of Study: Armed Forces Institute of Transfusion (AFIT), Rawalpindi Pakistan from Jul to Dec 2021. Methodology: Whole blood units were separated into red cell concentrates, fresh frozen plasma and random platelets by the platelet-rich plasma method. Cryoprecipitates were prepared from FFPs. Quality control was done on representative components. For red cell concentrates, hematocrit was measured. For platelet concentrates, pH and platelet yield were measured. For fresh frozen plasma, Factor-VIII assay and for cryoprecipitate, Factor VIII and fibrinogen assays were done. The blood components were also tested for bacterial cultures. Results: A total of 1130 units were analyzed for quality control, including 360 red cell concentrates, fresh frozen plasma, random donor platelets each and 50 cryoprecipitates. Red cell concentrates had a mean hematocrit of 68.5±3.7%. Random donor platelets had a yield of 10.1±1.4× 1010 / unit and a mean pH of 6.7±0.2. Fresh frozen plasma had a Factor VIII level of 2.2±0.98 IU/ml. Cryoprecipitate had a mean fibrinogen level of 202.8±27.8 mg/unit and Factor VIII132.5±54.1IU/unit. All blood components met internal quality control standards. Blood cultures were negative in 99.2% of random donor platelets tested. Conclusion: The internal quality control of blood products was in concordance with the national and international standards for quality control in blood banks.

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Section: Discussionmentioning

confidence: 99%

Assessment of Internal Quality Control of Blood Products; Experience at a Regional Transfusion Centre from Northern Pakistan

Khan

Tariq

Rathore

et al. 2022

PAFMJ

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“…All of the whole blood and PRBC units examined had volume and hemoglobin concentrations that were well within acceptable ranges, demonstrating the high caliber of our blood bank. In a study conducted by Upadhyay S et al [27], with results that are similar to those of this study, the mean volume of whole blood units was 410.81 mL with a range of 391-522 mL and the hematocrit of whole blood units was 43.73.2% with a range of 38-52.5% [27]. The hematocrit was 54.2% with a range of 41-69%, and the mean volume of PRBC units was 285.24 mL.…”

Section: Discussionmentioning

confidence: 99%

The impact of storage conditions on platelets in platelet-rich plasma (PRP) and platelet concentrate (PC)

Sriwastwa,

Shrivastava,

Ranjan

et al.

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Introduction:The ultimate aim of blood transfusion services is to give recipients whole blood and blood components that are secure, efficient, and potent. Control, assurance, and audit of quality are the foundational elements of quality. Product standards are developed and accurately met through the process of quality control. Method:In this study, samples of 2.3% PRBCs (50/2155), 9.3% platelet concentrate (42/451), and 3.6% of total whole blood collection (48/1,321) were prepared and tested for haematological parameters of quality control for the period from 1 January 2022 to 31 December 2022. Parameters for 8 samples of platelet concentrate available on day 5, were compared for day 0 and day 5. Result:Haematological metrics for whole blood, PRBCs, and platelet concentrate underwent quality examination. 50/2121, or 2.3% of the total whole blood collection, was used as a sample for the analysis of haematological parameters. Volume and haematocrit tests were performed on a total of 55 out of 2335 (2.3%) units. With a range of 344-365 mL, the average capacity was 358 mL. With a range of 35.1-48.0%, the mean haematocrit was 42.2%. Between 271 to 389 mL, the mean capacity was 311 mL. The range of the mean haematocrit was 57.3 to 81.9%. There was a slight decrease in volume, platelet count and WBC count of platelet concentrates on day 5 as compared to day 0. Conclusion:For effective and safe blood transfusion services, continuous quality improvement is crucial. Recommendation:Attention should be taken to applying consistent criteria for quality assessment, and objective analysis should be used regularly to verify that consistent values are being followed.

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Quality Analysis of Blood Component (Prbc and Platelet Concentrates): A Study From a Tertiary Care Teaching Hospital of Kumaon Region of Uttarakhand

Cited by 2 publications

References 7 publications

Assessment of Internal Quality Control of Blood Products; Experience at a Regional Transfusion Centre from Northern Pakistan

Assessment of Internal Quality Control of Blood Products; Experience at a Regional Transfusion Centre from Northern Pakistan

The impact of storage conditions on platelets in platelet-rich plasma (PRP) and platelet concentrate (PC)

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