A deeper understanding of wellness tourism management is possible by analyzing ‘well-being' from a more holistic perspective. “What is the reason for ‘well-being' to become such an emerging need in people's lives?” That is the question to respond to design a more sustainable and innovative managerial style in the wellness tourism sector. Holistic point of view considers the health of people in mutual interaction with its socio-economic and natural environment. For the managers with short-term and profit-based perspective, this sustainable managerial objective may seem difficult to grasp. However, multiple ways exist to create an improved vision of wellness tourism management beneficial for all stakeholders including the clientele, the employees, and the professionals of the wellness tourism sector. The theoretical and practical information on the spa resorts around the world are analyzed to reach the suggestions for improving wellness tourism management. Finally, an interview with an awarded wellness tourism manager supports the perspective of the chapter.