Quality assessment for systematic reviews and meta-analyses of cohort studies

Qumseya, Bashar J.

doi:10.1016/j.gie.2020.10.007

Cited by 29 publications

(19 citation statements)

References 44 publications

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“…The quality of the selected studies was evaluated using the Methodological Index for Nonrandomized Studies (MINORS) score [ 27 ]. The checklist includes 12 items, out of which the last four are specific to comparative studies.…”

Section: Methodsmentioning

confidence: 99%

Multiple revision anterior cruciate ligament reconstruction: not the best but still good

D’Ambrosi

Meena

Raj

et al. 2022

Knee Surg Sports Traumatol Arthrosc

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Purpose Given the paucity of literature on the re-revision of ACL, the current study was undertaken. The purpose of this systematic review was to synthesise and qualitatively assess the currently available evidence in the literature regarding the re-revision of ACL reconstruction (rrACLR). Methods A systematic review was conducted based on the PRISMA guidelines. The following search terms were used in the title, abstract and keywords fields: “ACL” or “anterior cruciate ligament” AND “revision” or “multiple” or “repeat”. The outcome data extracted from the studies were the Lysholm score, Subjective IKDC, Marx Score, Tegner, Marx Score, KOOS score, radiological changes and the rate of return to sports. Complications, failures and/or revision surgery were also analysed. Results The cohort consisted of 295 patients [191 (64.7%) men and 104 (35.3%) women] with a mean age of 29.9 ± 2.8 years (range 14–58 years) from 10 studies. The mean postoperative follow-up (reported in all studies except one) was 66.9 ± 44.7 months (range 13–230.4 months). Associated injuries were 103 (34.9%) medial meniscus tears, 57 (19.3%) lateral meniscus tears, 14 (4.7%) combined medial plus lateral meniscus tears, 11 (3.7%) meniscal tears (not specified), 252 (85.4%) cartilage lesions, 6 (2.0%) medial collateral ligament injury and 2 (0.7%) lateral collateral ligament injuries. In 47 (15.9%) patients an extra-articular plasty was performed for the anterolateral ligament. In all studies that reported pre- and post-operative IKDC (subjective and objective) and Lysholm score, there was a significant improvement compared to the pre-operative value (p < 0.05). At the final follow-up, laxity measured with KT-1000 was found to be 2.2 ± 0.6 mm. 31 (10.5%) out of 295 patients returned to their pre-injury activity level. A total of 19 (6.4%) re-ruptures were found, while only 4 (1.4%) complications (all minors) were reported, out of which 2 (0.7%) were superficial infections, 1 (0.3%) cyclops lesion and 1 (0.3%) flexion loss. Conclusion Multiple revisions of anterior cruciate ligament reconstruction allow acceptable clinical results and a good degree of knee stability with a low rate of subsequent new re-ruptures but the possibility of regaining pre-injury sports activity is poor; whenever possible, it is preferred to revise the ligament in one stage. This surgery remains a challenge for orthopaedic surgeons and many doubts persist regarding the ideal grafts, additional extra-articular procedures and techniques to use. Level of evidence IV. Study registration PROSPERO-CRD42022352164 (https://www.crd.york.ac.uk/prospero/).

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Section: Methodsmentioning

confidence: 99%

Multiple revision anterior cruciate ligament reconstruction: not the best but still good

D’Ambrosi

Meena

Raj

et al. 2022

Knee Surg Sports Traumatol Arthrosc

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“…Two reviewers (AP, MH) independently extracted eligible information into an a priori designed Google Excel sheet. The Qumseya scale for quality assessment of cohort studies for systematic reviews and meta-analyses consisted of nine questions 15 . We assessed each study for its design, measurements, outcomes, and patient characteristics.…”

Section: Methodsmentioning

confidence: 99%

“…Each risk of bias was judged on a maximum score of 10. Studies with less than six were considered low, 6 to 7 were moderate, and > 8 were considered high quality 15 .…”

Section: Methodsmentioning

confidence: 99%

“…Peri-procedural infections were <1% with 61 % of studies using peri-procedural antibiotics. Major adverse events outside tube dysfunction included major bleeding including hematoma (16), fistula (15), perforation (10), volvulus (8), severe infection such as peritonitis or abscess formation (7), and obstruction (6). Minor adverse events included outside tube leakage was minor bleeding (78), pain (27), aspiration (17), minor bleeding (11), ileus (4), and ulcers (2).…”

Section: E517mentioning

confidence: 99%

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Direct percutaneous endoscopic jejunostomy (DPEJ) and percutaneous endoscopic gastrostomy with jejunal extension (PEG-J) technical success and outcomes: Systematic review and meta-analysis

et al. 2022

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Background and study aims Endoscopic methods of delivering uninterrupted feeding to the jejunum include direct percutaneous endoscopic jejunostomy (DPEJ) or PEG with jejunal extension (PEG-J), validated from small individual studies. We aim to perform a meta-analysis to assess their effectiveness and safety in a variety of clinical scenarios. Methods Major databases were searched until June 2021. Efficacy outcomes included technical and clinical success, while safety outcomes included adverse events (AEs) and malfunction rates. We assessed heterogeneity using I2 and classic fail-safe to assess bias. Results 29 studies included 1874 patients (983 males and 809 females); mean age of 60 ± 19 years. Pooled technical and clinical success rates with DPEJ were 86.6 % (CI, 82.1–90.1, I2 73.1) and 96.9 % (CI, 95.0–98.0, I2 12.7). The pooled incidence of malfunction, major and minor AEs with DPEJ were 11 %, 5 %, and 15 %. Pooled technical and clinical success for PEG-J were 94.4 % (CI, 85.5–97.9, I2 33) and 98.7 % (CI, 95.5–99.6, I2 < 0.001). The pooled incidence of malfunction, major and minor AEs with DPEJ were 24 %, 1 %, and 25 %. Device-assisted DPEJ performed better in altered gastrointestinal anatomy. First and second attempts were 87.6 % and 90.2 %. Conclusions DPEJ and PEG-J are safe and effective procedures placed with high fidelity with comparable outcomes. DPEJ was associated with fewer tube malfunction and failure rates; however, it is technically more complex and not standardized, while PEG-J had higher placement rates. The use of balloon enteroscopy was found to enhance DPEJ performance.

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“…Each risk of bias had a maximum score of 10. Studies with less than six were considered low, 6-7 were moderate, and > 8 were deemed to be high quality[ 16 ].…”

Section: Methodsmentioning

confidence: 99%

Spontaneous bacterial empyema in cirrhosis: A systematic review and meta-analysis

Reiche¹,

Deliwala²,

Chandan³

et al. 2022

WJH

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BACKGROUND Spontaneous bacterial empyema (SBE) occurs when a hepatic hydrothorax becomes infected and runs a course similar to spontaneous bacterial peritonitis (SBP). It remains underdiagnosed as patients with cirrhosis do not routinely undergo diagnostic thoracentesis. Current understanding is limited by small cohorts, while studies reporting its association with ascites/SBP are conflicting. AIM To explore the incidence of SBE, to determine its association with ascites, and to summarize what is known regarding treatment and outcomes for patients with SBE. METHODS Major databases were searched until June 2021. Outcomes include the incidence of SBE in pleural effusions, SBP in peritoneal fluid, and SBE in patients without ascites within our cohort of patients with cirrhosis. We performed a meta-analysis using a random-effects model with pooled proportions and 95% confidence intervals (CI). We assessed heterogeneity using I 2 and classic fail-safe to determine bias. RESULTS Eight studies with 8899 cirrhosis patients were included. The median age ranged between 41.2 to 69.7 years. The majority of the patients were Child-Pugh B and C. Mean MELD score was 18.6 ± 8.09. A total of 1334 patients had pleural effusions and the pooled incidence of SBE was 15.6% (CI 12.6-19; I 2 50). Amongst patients diagnosed with SBE, the most common locations included right (202), left (64), and bilateral (8). Amongst our cohort, a total of 2636 patients had ascites with a pooled incidence of SBP of 22.2% (CI 9.9-42.7; I 2 97.8). The pooled incidence of SBE in patients with cirrhosis but without concomitant ascites was 9.5% (CI 3.6-22.8; I 2 82.5). CONCLUSION SBE frequently occurs with concurrent ascites/SBP; our results suggest high incidence rates of SBE even in the absence of ascites. The pleura can be an unrecognized nidus and our findings support the use of diagnostic thoracentesis in patients with decompensated cirrhosis after exclusion of other causes of pleural effusion. Thoracentesis should be considered particularly in patients without ascites and when there is a high suspicion of infection. The need for diagnostic thoracentesis will continue to be important as rates of multi-drug resistant bacterial infections increase and antibiotic susceptibility information is required for adequate treatment.

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Quality assessment for systematic reviews and meta-analyses of cohort studies

Cited by 29 publications

References 44 publications

Multiple revision anterior cruciate ligament reconstruction: not the best but still good

Multiple revision anterior cruciate ligament reconstruction: not the best but still good

Direct percutaneous endoscopic jejunostomy (DPEJ) and percutaneous endoscopic gastrostomy with jejunal extension (PEG-J) technical success and outcomes: Systematic review and meta-analysis

Spontaneous bacterial empyema in cirrhosis: A systematic review and meta-analysis

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