2024
DOI: 10.25004/ijpsdr.2024.160214
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Quality-by-Design Optimization of Electrospinning Parameters to Formulate Scaffolds for Topical Inflammatory Disease Management <i>via</i> Drug Repurposing

Alka,
Shubhini A. Saraf

Abstract: This study investigates the fabrication of chitosan (CS)/polyvinyl alcohol (PVA) blend nanofibers via electrospinning, aiming to create nanofibers with enhanced properties for broad applications. The research focuses on optimizing electrospinning parameters to reduce bead formation and achieve uniform nanofiber morphology. A detailed experimental design, employing a nineteen-point plan developed with Design-Expert software, examined variables such as polymer concentration, distance from the needle to the colle… Show more

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