Marine fish is an excellent source of nutrition but also
contributes
the most to human exposure to methylmercury (MMHg), a neurotoxicant
that poses significant risks to human health on a global scale and
is regulated by the Minamata Convention. To better predict human exposure
to MMHg, it is important to understand the trophic transfer of MMHg
in the global marine food webs, which remains largely unknown, especially
in the upper trophic level (TL) biota that is more directly relevant
to human exposure. In this study, we couple a fish ecological model
and an ocean methylmercury model to explore the influencing factors
and mechanisms of MMHg transfer in marine fish food webs. Our results
show that available MMHg in the zooplankton strongly determines the
MMHg in fish. Medium-sized fish are critical intermediaries that transfer
more than 70% of the MMHg circulating in food webs. Grazing is the
main factor to control MMHg concentrations in different size categories
of fish. Feeding interactions affected by ecosystem structures determine
the degree of MMHg biomagnification. We estimate a total of 6.1 metric
tons of MMHg potentially digested by the global population per year
through marine fish consumption. The model provides a useful tool
to quantify human exposure to MMHg through marine fish consumption
and thus fills a critical gap in the effectiveness evaluation of the
convention.