Considering the potential consumption and economic the importance that Osabella and Oves wines represent in the Brazilian consumer market as well as the scarcity of scientific data examining their quality, the objective of this study was to investigate the sensory quality and the volatiles profile of these wines. The volatile compounds were extracted by headspace solid-phase microextraction (HS-SPME) and a total of 54 compounds were detected in red wine samples including esters (23), terpenes (12), alcohols (10), aldehydes and ketones (5) and amines (1) as well as 3 compounds belonging to other classes. Osabella and Oves red wines were sensorially characterized by 14 descriptors, through quantitative descriptive analysis (QDA). The PCAs fruity descriptors were the primary contributors to the aroma profile of the analyzed wines due to the presence of ethyl acetate and esters, especially in the wine coded as QM, which exhibited the highest variety of compounds. The differences observed in the principal components analysis, might have been influenced by the grape composition of each wine. Although the wines were from the same region, each came from a different winery and was subject to unique production processes.Keywords: aroma enology; extraction; fermented drink; mass spectrometry.Practical Application: Data of volatile compounds profile and aroma descriptors of red wines are of great importance in understanding the positive and negative aromatic quality of wines that direct affects the acceptance and/or rejection of wines by the consumers. Futhermore, it is important to emphasize that these results contribute to enhancing scientific knowledge on aromatic quality of red wines produced with Brazilian Osabella and Oves cultivars.