Quality in diagnostic upper gastrointestinal endoscopy for the detection and surveillance of gastric cancer precursor lesions: Position paper of AEG, SEED and SEAP

Fernández‐Esparrach, Glòria; Marín-Gabriel, José Carlos; Redondo, Pilar Díez; Núñez, Henar; Santiago, Enrique Rodríguez de; Rosón, Pedro; Calvet, Xavier; Cuatrecasas, Míriam; Cubiella, Joaquín; Moreira, Letícia; López, M. Luisa Pardo; Aísa, Ángeles Pérez; Sanz‐Anquela, José Miguel

doi:10.1016/j.gastre.2021.05.001

Cited by 3 publications

(3 citation statements)

References 112 publications

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“…General intravenous anesthesia is mostly used in radical surgery, comprising operations such as tracheal intubation during anesthesia. That would stimulate the sympathetic nerves, and induce strong stress reactions, hemodynamic changes and frequent brain electrical activities, which have adverse effects on the cardiovascular system and the smooth progress of surgery (8,9). In addition, patients who undergo radical surgery generally experience a certain amount of pain, mechanical stress in the gastrointestinal tract and local tissue damage, which will release a large amount of inflammatory mediators, increasing the incision infection, lung infection and other complications rates (10,11).…”

Section: Discussionmentioning

confidence: 99%

Application of Dexmedetomidine in Surgical Anesthesia for Gastric Cancer and Its Effects on IL-1β, IL-6, TNF-α and CRP

Zheng¹,

Tian²,

Fan³

et al. 2023

Cell Mol Biol (Noisy-le-grand)

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Section: Discussionmentioning

confidence: 99%

Application of Dexmedetomidine in Surgical Anesthesia for Gastric Cancer and Its Effects on IL-1β, IL-6, TNF-α and CRP

Zheng¹,

Tian²,

Fan³

et al. 2023

Cell Mol Biol (Noisy-le-grand)

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“…Contrarily to other syndromes, such as in HDGC where the surveillance is better established, 21,22 in FIGC there is no clear evidence for the best approach. Surveillance is recommended in a research environment, 23 and recommendations vary between different European societies, from just eradicating Hp , to performing endoscopies with different periodicities (annually, every 3 or 5 years) 2,4,24‐27 . For example, the European Society of Digestive Oncology expert panel recommends annual EGD with a detailed exploration of the gastric mucosa with random biopsies, starting at the latest at the age of 40 years or 5 years before disease onset in the youngest affected relative 24 .…”

Section: Introductionmentioning

confidence: 99%

“…Surveillance is recommended in a research environment, 23 and recommendations vary between different European societies, from just eradicating Hp, to performing endoscopies with different periodicities (annually, every 3 or 5 years). 2,4,[24][25][26][27] For example, the European Society of Digestive Oncology expert panel recommends annual EGD with a detailed exploration of the gastric mucosa with random biopsies, starting at the latest at the age of 40 years or 5 years before disease onset in the youngest affected relative. 24 However, there are no studies evaluating the effectiveness of the endoscopic assessment in FIGC.…”

Section: Introductionmentioning

confidence: 99%

Endoscopic surveillance for familial intestinal gastric cancer in low‐incidence areas: An effective strategy

Llach,

Salces,

Guerra

et al. 2023

Intl Journal of Cancer

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While clinical practice guidelines for hereditary diffuse gastric cancer are well established, there is no consensus on the approach for familial intestinal gastric cancer (FIGC). In low‐incidence gastric cancer (GC) areas such as the United States or most European countries, there are no evidence‐based recommendations on endoscopic assessment in FIGC families. We aim to describe the yield of GC surveillance in these families, and to identify epidemiological risk factors for the development of GC and its precursor lesions. This is a multicenter observational study involving nine tertiary Spanish hospitals, in which all individuals fulfilling FIGC criteria who underwent endoscopic surveillance were included between 1991 and 2020. Forty‐one healthy individuals of 31 families were recruited. The median number of upper gastrointestinal endoscopies per individual was 3 (interquartile range, IQR, 1‐4). The median interval time between tests was 2 years (IQR 1.5‐2.5), and the median follow‐up was 9 years (IQR 3‐14.5). In 18 (43.9%) subjects, a precursor lesion of GC was found during follow‐up, and in 2 (4.9%), an early GC was identified, in which curative treatment was offered. Helicobacter pylori (Hp) infection proved to be independently associated with an increased risk of developing precursor lesions or GC, adjusted by age, gender and follow‐up, with an Odds Ratio of 6.443 (1.36‐30.6, P value .019). We present the first outcomes that support endoscopic surveillance with biopsies and detection of Hp in FIGC families, although the periodicity has yet to be defined.

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Cáncer gástrico, últimos avances en el manejo; presentación de caso clínico

Urgilés Rivas,

Correa Coronel,

Peñaloza Minchala

et al. 2024

REVMIC

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The current problem of advanced gastric cancer is its high morbimortality, it represents the fifth most frequent tumor and the fourth cause of death, surgical treatment determines a benefit in the survival of the patient, however, most tumors at the time of diagnosis are in advanced stages resulting ineffective surgical procedure, we present the case of an 82-year-old male patient, consulting for abdominal distention, unquantified weight loss and hyporexia. Endoscopy revealed a tumor lesion whose histological report was gastric adenocarcinoma, so a total gastrectomy and subsequent chemotherapy were performed, he presented a torpid evolution and finally died. Conclusion: multiple factors influence the genesis of the tumor; gastrectomy is still the standard of treatment in early stages but most cases are in advanced stages

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Quality in diagnostic upper gastrointestinal endoscopy for the detection and surveillance of gastric cancer precursor lesions: Position paper of AEG, SEED and SEAP

Cited by 3 publications

References 112 publications

Application of Dexmedetomidine in Surgical Anesthesia for Gastric Cancer and Its Effects on IL-1β, IL-6, TNF-α and CRP

Application of Dexmedetomidine in Surgical Anesthesia for Gastric Cancer and Its Effects on IL-1β, IL-6, TNF-α and CRP

Endoscopic surveillance for familial intestinal gastric cancer in low‐incidence areas: An effective strategy

Cáncer gástrico, últimos avances en el manejo; presentación de caso clínico

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