Quality of anticoagulation with warfarin in patients with nonvalvular atrial fibrillation in the community setting

Dose-adjusted warfarin: writing the prescription is only the beginning

“…13 The rates they report are consistent with others in similar settings (approximately 55%), and in older studies. We are not significantly better at maintaining high TTR in 2012, than in prior eras.…”

International Normalized Ratio Variability: A Measure of Anticoagulation Quality or a Powerful Mortality Predictor

“…[5][6][7][8][9][10] The INR variability estimates the deviation of INR from the intended range over time and is based on the hypothesis that patient's prothrombin time fluctuates all the time, and its value is a risk indicator for thromboembolism and major hemorrhage.…”

“…Mortality rates were also significantly lower with at least 70% of time spent within therapeutic range. 1,7,9 In another work, the SD INRs was a better predictor of mortality, stroke, bleeding, and hospitalization than the TTR in patients with AF receiving warfarin therapy. 20 Other similar techniques to evaluate INR variability had shown similar results.…”

“…3 Long periods with a TTR above 65% or a high percentage of INRs (%INRs) in range are associated with reduction in hemorrhage and thromboembolic events. [4][5][6][7][8][9][10][11] Therefore, monitoring INR variability to assess and correct warfarin treatment decreases complications. 1 In our country and the rest of South America, there is no sufficient information regarding anticoagulation quality in patients receiving warfarin.…”

Grado de control del tratamiento anticoagulante oral en los centros de Atención Primaria de la Comunidad de Madrid: estudio CHRONOS-TAO

“…Los resultados obtenidos son iguales o mejores a los de la mayoría de estudios similares 21,22,[25][26][27][28]31 (tabla 3), a excepció n del estudio sueco 27 , que obtiene un nivel de calidad superior al resto. Tambié n son similares o mejores a los obtenidos en los ensayos clínicos de los NAO [32][33][34][35] , lo cual sorprende, ya que en un ensayo clínico el control de los aVK se realizaría con un seguimiento má s estrecho de los pacientes que en la prá ctica clínica habitual.…”