“…Nonetheless, the incorporation of these advances in clinical practice tends to be slow. As a result, several studies investigating HF 4,5 and other conditions 6,7 have reported a discrepancy between the accepted approaches published in clinical practice guidelines and the activity seen in regular clinical practice. With regard to HF, the gap between recommendations and what is done in clinical practice is much smaller now than in previous years, after justified reasons for not administering a recommended therapy have been taken into account.…”