Quality of health in survivors of childhood acute myeloid leukemia treated with chemotherapy only: A NOPHO‐AML study

Abstract

The self-reported health of children treated on NOPHO-AML protocols without HSCT was good, and their use of health care services was limited. Reported health and social outcomes were comparable to those of their siblings. Many survivors were smoking which may increase the risk of late effects.

Gemtuzumab ozogamicin as postconsolidation therapy does not prevent relapse in children with AML: results from NOPHO-AML 2004

“…Second malignant neoplasms are rare in pediatric AML with a 15-year cumulated incidence of less than 2%. 23,24 GO is not known to be associated with secondary malignancies and our observation may be a chance finding.…”

Employment in French young adult survivors of childhood leukemia: an LEA study (for Leucemies de l’Enfant et de l’Adolescent—childhood and adolescent leukemia)

“…A report from the Childhood Cancer Survivor Study found that adult childhood cancer survivors were employed in lower-skilled jobs than their siblings [21]. A study including survivors of childhood myeloblastic AL treated by chemotherapy only reported that the number of full-time employees was significantly lower among the survivors than among their siblings [23]. However, the authors noted a higher proportion of students among the survivors.…”

“…are clearly differentiated. Many previous studies that have explored the employment status of childhood cancer survivors have reported their results concerning unemployed survivors without differentiating, for example, students or those not working by choice [6,17,20,22,23,31,32]. In our study, active childhood AL survivors (currently on the labor market) were compared to the active general French population to explore the potential difficulties in accessing employment for the survivors who were likely to work.…”

“…However, when childhood cancer survivors obtain employment, the literature on their occupational achievements is rather sparse. While specific job types, skill requirements, and part-vs full-time employment have been explored in a few studies [21,23], no data about the stability of the survivors' employment are available.…”

Development of treatment and clinical results in childhood acute myeloid leukemia in Poland

“…Introduction of targeted treatment modalities could allow a better stratification of patients, and use of more individualized therapies may lead to further improvements of treatment outcomes. The new treatment protocols for children with AML are expected to improve the treatment results and decrease the late side effect rates [13, 14, 29, 30]. However, further progress in AML therapy seems possible because of continued cooperation of oncology centers within large international study groups.…”