Quality of life after indefinite diversion/pouch excision in ileal pouch failure patients

Das, P.; Smith, Jason; Tekkis, Paris; Heriot, Alexander G.; Antropoli, Massimo; Nicholls, R. J.

doi:10.1111/j.1463-1318.2007.01216.x

Cited by 28 publications

(17 citation statements)

References 36 publications

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“…However, there are only a few reports on HQoL for patients with pouch failure. 7,48 In the study by Das et al, 22 both patients with excised pouches and patients with diverted pouches showed lower scores than the UK norm in all domains of the SF-36; there was however no difference between the groups. In a study by Lepisto et al, 48 18/21 patients with pouch failure answered the SF-36 instrument and were compared with controls and with 19 persons from the Finish norm database.…”

Section: Health-related Quality Of Lifementioning

confidence: 92%

“…To our knowledge, only the study by Das et al has addressed the issue. 22 Ninety-seven patients (56 women) with pouch failure were included in that study; focus was on potential differences between patients undergoing pouch excision or definitive diversion. Fifty-three patients (36 women) answered the posted questionnaires on HQoL (e.g.…”

Section: Sexual Functionmentioning

confidence: 99%

“…7 To our knowledge, there is only one study reporting on details of sexual function in patients with pouch failure. 22 Since the majority of patients with IPAA are young and the failure rate is substantial, we consider this aspect to be important to explore.…”

Section: Introductionmentioning

confidence: 99%

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Sexual function after failed ileal pouch-anal anastomosis

Bengtsson¹,

Lindholm²,

Nordgren³

et al. 2011

Journal of Crohn's and Colitis

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Background and Aims: Failure of ileal pouch-anal anastomosis (IPAA) occurs in around 10% of the patients. Compared to patients with functioning pouches, health related quality of life is deteriorated after failure. Sexual function in patients with pouch failure is however poorly studied. The aim was to study sexual function in patients with pelvic pouch failure; patients with functioning pouches were used as controls. The hypothesis was that patients with pouch failure have worse sexual function. Methods: 36 patients with pouch failure were compared with 72 age and sex-matched controls with ulcerative colitis and functioning pouches. The patients answered a set of questionnaires concerning sexual function (Female Sexual Function Index [FSFI] and International Index of Erectile Function [IIEF]), body image (BIS-scale) and health-related quality of life (SF-36). Results: Both women and men with pouch failure scored lower than controls in the FSFI and IIEF questionnaires. However, none of the observations were statistically significant. The scores in the failure group (for both sexes) were below the cut-off level for sexual dysfunction. Scores for the BIS instrument were significantly lower for both sexes in the failure group. Women and men in the failure group scored lower than the controls in all domains of the SF-36, however statistically significant only for the social function domain in men. Conclusions: The hypothesis, that a failed IPAA is associated with worse sexual function, was not confirmed. Compared to patients with functioning pouches, patients with pouch failure have inferior body image.

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Section: Health-related Quality Of Lifementioning

confidence: 92%

Section: Sexual Functionmentioning

confidence: 99%

See 1 more Smart Citation

Sexual function after failed ileal pouch-anal anastomosis

Bengtsson¹,

Lindholm²,

Nordgren³

et al. 2011

Journal of Crohn's and Colitis

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show abstract

“…Letztere ist nur für die wenigen Patienten geeignet, deren Rektum relativ entzündungsfrei ist und die keine Dysplasie oder ein bestehendes Karzinom im Rektum [4] haben. Die konventionelle Proktokolektomie lässt den Patienten mit einem permanenten Ileostoma zurück [5]. Aktuell ist die RPC in der Behandlung von CU die chirurgische Methode der Wahl [6].…”

Section: Dysplasie Und Adenokarzinome Im Ileum-pouch Nach Restaurativunclassified

Dysplasie und Adenokarzinome im Ileum-Pouch nach restaurativer Proktokolektomie wegen Colitis ulcerosa

M’Koma

2011

coloproctology

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“…Minimal information is currently available pertaining to the relative roles of these 2 surgical options for pouch failure, and especially their influence on QOL. 12,13 One of these studies 12 only reported outcomes after LI, and both studies 12,13 suffer from the drawbacks of small numbers and short follow-up. Based on the identification of this current gap in the literature, we chose to specifically evaluate the surgical outcomes and QOL after LI for pouch failure in comparison with PE for a large number of patients with prolonged follow-up.…”

mentioning

confidence: 96%