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Conflicto de intereses: los autores declaran no tener conflictos de interés.Inteligencia artificial: los autores declaran no haber usado inteligencia artificial (IA) ni ninguna herramienta que use IA para la redacción del artículo. RESUMENEl tratamiento del cáncer de cabeza y cuello (CCC) puede tener un impacto significativo en la calidad de vida (CV). Su valoración a través de cuestionarios es un importante aspecto en la evaluación clínica y terapéutica de los pacientes. Existe un interés creciente en la valoración de la CV en CCC mediante cuestionarios estandarizados puesto que, junto con la recurrencia y la supervivencia, ayuda a comprender los resultados del tratamiento. Los estudios revelan qué factores del paciente (edad, sexo, comorbilidades, etc.), qué tipo de tumor (localización, tamaño, etc.) y qué tipo de tratamiento (cirugía, radioquimioterapia, etc.) están asociados con la CV. Aunque las puntuaciones globales de CV suelen disminuir tras el tratamiento, en general suelen recuperarse con el tiempo. La valoración de la CV se ha convertido en un parámetro adicional a considerar en el cuidado y en el manejo de supervivientes de CCC. Es necesario evaluar sus resultados a largo plazo, ya que los pacientes pueden requerir mucho tiempo para recuperarse de la enfermedad y de los efectos adversos del tratamiento.Palabras clave: Calidad de vida. Cáncer de cabeza y cuello. Calidad de vida relacionada con la salud. Supervivientes. Cuestionarios.
Conflicto de intereses: los autores declaran no tener conflictos de interés.Inteligencia artificial: los autores declaran no haber usado inteligencia artificial (IA) ni ninguna herramienta que use IA para la redacción del artículo. RESUMENEl tratamiento del cáncer de cabeza y cuello (CCC) puede tener un impacto significativo en la calidad de vida (CV). Su valoración a través de cuestionarios es un importante aspecto en la evaluación clínica y terapéutica de los pacientes. Existe un interés creciente en la valoración de la CV en CCC mediante cuestionarios estandarizados puesto que, junto con la recurrencia y la supervivencia, ayuda a comprender los resultados del tratamiento. Los estudios revelan qué factores del paciente (edad, sexo, comorbilidades, etc.), qué tipo de tumor (localización, tamaño, etc.) y qué tipo de tratamiento (cirugía, radioquimioterapia, etc.) están asociados con la CV. Aunque las puntuaciones globales de CV suelen disminuir tras el tratamiento, en general suelen recuperarse con el tiempo. La valoración de la CV se ha convertido en un parámetro adicional a considerar en el cuidado y en el manejo de supervivientes de CCC. Es necesario evaluar sus resultados a largo plazo, ya que los pacientes pueden requerir mucho tiempo para recuperarse de la enfermedad y de los efectos adversos del tratamiento.Palabras clave: Calidad de vida. Cáncer de cabeza y cuello. Calidad de vida relacionada con la salud. Supervivientes. Cuestionarios.
Background: This study evaluates the general and specific quality of life (QoL) in oral cancer patients with more than 5 years of survival after initial surgery and reconstructed with Radial Forearm Free Flap (RFFF), comparing these results with a general population group, used as a reference.Methods: We used in our study the SF36 (Short Form 36), the UW (University of Washington) and the EORTC-H&N35 (European Organisation for Research and Treatment of Cancer, Head and Neck 35) QoL questionnaires, self-administered to 30 oral cancer patients reconstructed with RFFF, and at least 5 years of cancer-free survival after surgery. Paired Student t test and Student t test to compare a sample with a theoretical value or Wilconxon test to compare a sample with a theoretical value, when indicated, were used to analyze the statistical significance, which was considered at a value of p<0.05.We applied the Minimum Important Difference (MID) to the difference of means between our patients and the general population. The difference of means was considered clinically relevant if it overcame the MID.Results: The SF-36 questionnaire in our patients yielded a better HRQL (Health Related Quality of Life), both statistically significant and clinically relevant in physical limitation and pain dimension, and statistically significant in emotional limitation dimension when compared to general population. At EORTC-H&N35 questionnaire, our patients presented clinically relevant negative differences and statistically significant scores in specific dimensions of the oral cavity. With UW questionnaire, anxiety dimension scored the best, with clinically and statistically significant differences versus general population. The other dimensions showed clinically and statistically significant worst results than general population.Conclusions: Our patient´s General QoL is similar or even better in some dimension than general population. However, most specific dimensions presented clinically and statistically worst results than general population.
(1) Background: This prospective study aimed to assess the impact on quality of life (QoL) from pretreatment to 3 years after treatment in oropharyngeal carcinoma (OPC) survivors. (2) Methods: QoL was measured with the EORTC QLQ-C30 and EORTC QLQ-H&N35 scales before treatment and in the first and third years. (3) Results: Of 72 patients, 51 completed all questionnaires over 3 years. A variable deterioration of QoL scores was detected before treatment. Most items worsened significantly after treatment and during the first year and improved in the third year. Advanced-stage cancer and definitive chemoradiotherapy treatment showed the worst scores. At 3 years, patients who underwent surgery with adjuvant radiation therapy/chemotherapy had significantly better scores on global QoL and emotional functioning compared to those treated with definitive chemoradiotherapy, who also reported problems with sticky salivation and dry mouth. Patients treated with an open surgical approach showed significantly greater deterioration in physical and role functioning compared to transoral surgery. (4) Conclusions: This long-term prospective study is the first in Spain to use EORCT scales in a homogeneous group of OPC survivors. QoL was generally good, although patients needed a long period of time to recover from both cancer and side effects of treatment. Advanced-stage cancer and definitive chemoradiotherapy showed the worst scores.
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