Quality of life among head and neck cancer treated patients in South India: A cross-sectional study

Barma, Manali Deb; Indiran, Meignana Arumugham; Kumar, P.; Balasubramaniam, Arthi; Kumar, Manoj

doi:10.1016/j.jobcr.2021.02.002

Cited by 13 publications

(6 citation statements)

References 22 publications

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“…The age group more susceptible to developing HNC is below 52 years (51.9%) correlating with other study by Chauhan et al 39 which assessed the prevalence and pattern of tobacco consumption before the development of HNC. However, patients aged above 52 years experienced a greater burden of oral complications following cancer treatment, which was evident through their significantly higher mean score for OHRQoL 26.4 ± 14.8 similar to the findings reported by Barma et al 40 and Lee et al 41 Participants who were underweight i.e. < 18.5 kg/m 2 were more adversely affected with a OHRQoL score of 33.33 ± 13.81 which can be possibly due to the disturbance in daily eating and sleeping patterns because of oral complications, similar to findings reported by Huang et al 42 indicating significantly lowered OHRQoL in HNC patients who were underweight.…”

Section: Discussionsupporting

confidence: 86%

Oral health related quality of life in head and neck cancer survivors within the first year following treatment: a cross-sectional study in Karachi, Pakistan

Qamar,

Rozi,

Sawani

et al. 2024

Sci Rep

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After completing treatment for head and neck cancer (HNC), patients often face oral complications like oral pain, limited mouth opening and dry mouth which significantly reduce their oral health related quality of life (OHRQoL). These issues impact their overall well-being, social activities and long-term survival. The primary objective of this study was to evaluate OHRQoL and its association with sociodemographic characteristics, oral hygiene practices and oral clinical parameters such as oral hygiene status and oral mucositis grade in patients who have completed treatment for head and neck cancer. This cross-sectional study involved 79 HNC-treated patients within first year after completion of cancer treatment attending ENT and dental clinics at outpatient department (OPD) setting in Karachi. Data was collected electronically using structured questionnaire comprising of EORTC QLQ H&N – 35 to measure OHRQoL, patients were also examined for oral hygiene status using oral hygiene index- simplified (OHI-s) and oral mucositis grade using WHO oral mucositis scale. Multiple linear regression was used to test OHRQoL associations with the sociodemographic and different clinical factors. The result showed an overall mean score for oral health related quality of life (OHRQoL) of 25.02 ± 15.86 (95% CI 21.46–28.57), with difficulty in mouth opening 53.16 ± 18.88 and dry mouth 45.14 ± 24.48 being predominant concerns for decline in the OHRQoL in the population. Male predilection was observed among participants n = 60 (75.9%), majority of the participants n = 41 (51.9%) were below 52 years of age. n = 63 (80%) participants received radiotherapy alongside surgery and chemotherapy. Most of participants n = 66 (83.5%) experienced moderate to severe oral mucositis with poor oral hygiene status n = 56 (71%). Significant associations were found between OHRQoL and BMI, OH status, marital status, monthly income, gender and fluoride toothpaste (p < 0.05). These findings suggest that Quality of Life (QoL) among HNC treated patients is negatively impacted by their poor oral health, post cancer treatment. Therefore, it is important to evaluate and modify the current treatment modalities and involve multidisciplinary teams, to improve their OHRQoL thereby enhancing overall QoL.

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Section: Discussionsupporting

confidence: 86%

Oral health related quality of life in head and neck cancer survivors within the first year following treatment: a cross-sectional study in Karachi, Pakistan

Qamar,

Rozi,

Sawani

et al. 2024

Sci Rep

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“…The current analyses showed an overall high mean score of OHRQoL, i.e., 25.02 ± 15.86 compared with the other studies we found (17,25), suggesting worsened oral symptoms during the rst year of treatment in our population, which can be due to a lack of resources and proper oral care given to these patients for the treatment of their oral symptoms after the cancer therapy. Also, the patients are guided about the maintenance of their oral hygiene, which can help relieve their pain and reduce the severity of acute oral complications.…”

Section: Discussioncontrasting

confidence: 57%

Assessment of Oral health related quality of life and its associated factors in head and neck cancer survivors, within one-year, post cancer treatment. A cross-sectional study

Farrukh,

Rozi,

Sawani

et al. 2023

Preprint

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Background Patients after completing their treatment for HNC, are often functionally challenged by the acute and chronic complications in the oral cavity such as oral pain, limited mouth opening, xerostomia etc. These complications are known to reduce their OHRQoL, because of restricted food intake, limited social activity and economic growth, therefore impacting their overall well-being and survival. This study aims to assess the OHRQoL and its associated sociodemographic factors, oral hygiene related factors and oral clinical parameters such as OH status and OM grade in HNC survivors within one-year post cancer treatment.Methodology This was a cross-sectional study performed among HNC survivors at the ENT and dental clinics of Aga Khan University Hospital, Karachi. OHRQoL was assessed using EORTC QLQ H&N – 35, patients were examined for oral hygiene status using OHI- simplified and oral mucositis grade using WHO oral mucositis scale at one point in time. One sample t- test and multiple linear regression was used to test OHRQoL and its associations with the sociodemographic and clinical factors.Results The results of the study showed an overall higher mean score for OHRQoL of 25.02 ± 15.86 (95% CI 21.46–28.57), with difficulty in mouth opening and dry mouth because of salivary dysfunction among the most affected domains with higher symptoms scores in the study population. Significant association of OHRQoL were found with BMI, OH status, marital status, monthly income, gender and fluoride toothpaste use in HNC patients within one-year post cancer treatment (p < 0.05).Conclusion: High mean score for OHRQoL in HNC patients suggests their QoL is negatively impacted by their poor oral health post cancer treatment, therefore it is important to evaluate and modify the current treatment modalities and involve multidisciplinary teams, to improve their OHRQoL thereby enhancing overall QoL.

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“…However, the severity of mucositis depends on the dose of radiotherapy and the type of tissues. Mucositis develops in people who receive radiotherapy, which greatly affects their quality of life and increases their need for psychological treatment [ 17 , 18 ].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of recurrence, mortality and treatment complications of oral squamous cell carcinoma in public health centers in Shiraz during 2010 to 2020

et al. 2023

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Introduction Oral Squamous cell Carcinoma (OSCC) is the most common oral cancer and is treated with surgery, radiotherapy and chemotherapy. Various complications of treatment include xerostomia, mucositis, and trismus, which affect patients’ quality of life. The aim of this study is to evaluate the mortality, recurrence rate and prevalence of oral complications in treated patients. Method and materials This cross-sectional study reviewed 326 cases of patients with OSCC who were referred to public health centers in Shiraz (Khalili Hospital and Dental School) from 2010 to 2020. All patients were contacted, and the survivors were called and examined by an oral physician. A medical record was created for them, including demographic information, location of the lesion, type of treatment, history of recurrence, metastasis and oral complications. Results 53.5% of patients were male and 46.5% were female. The mean age of patients was 58.68 years. Mortality and recurrence rate was respectively 49.8% and 17.8%. The most common location of the lesion was tongue (64%). Surgery was done for all patients. 97.4% of patients complained of xerostomia, 46.2% of mucositis and 44.3% of trismus. Conclusion The most common complications of treatment are xerostomia, mucositis, and trismus, respectively. Frequent and regular follow-ups and supportive therapies reduce these complications and improve patients’ quality of life.

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Quality of life among head and neck cancer treated patients in South India: A cross-sectional study

Cited by 13 publications

References 22 publications

Oral health related quality of life in head and neck cancer survivors within the first year following treatment: a cross-sectional study in Karachi, Pakistan

Oral health related quality of life in head and neck cancer survivors within the first year following treatment: a cross-sectional study in Karachi, Pakistan

Assessment of Oral health related quality of life and its associated factors in head and neck cancer survivors, within one-year, post cancer treatment. A cross-sectional study

Evaluation of recurrence, mortality and treatment complications of oral squamous cell carcinoma in public health centers in Shiraz during 2010 to 2020

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