Quality of life and assessment after local application of sulphurous water in the home environment in patients with psoriasis vulgaris: A randomised placebo-controlled pilot study

Galve, Juan José Gálvez; Peiró, Pablo Saz; Lucas, María Ortiz; Torres, Antonio Hernández; Gil, Estrella Simal; Pérez, Milagros Bernal

doi:10.1016/j.eujim.2012.01.001

Cited by 16 publications

(3 citation statements)

References 14 publications

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“…Sulphurous spa baths have been used successfully for immunomediated conditions such as contact dermatitis, psoriasis, and atopic dermatitis, and it has been recently suggested that the active principles of sulphurous mineral waters could play a role in immune regulation in the skin [ 59 ].…”

Section: Topical Transformations and Hazardsmentioning

confidence: 99%

Sulphurous Mineral Waters: New Applications for Health

Carbajo

Maraver

2017

Evidence-Based Complementary and Alternative Medicine

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Sulphurous mineral waters have been traditionally used in medical hydrology as treatment for skin, respiratory, and musculoskeletal disorders. However, driven by recent intense research efforts, topical treatments are starting to show benefits for pulmonary hypertension, arterial hypertension, atherosclerosis, ischemia-reperfusion injury, heart failure, peptic ulcer, and acute and chronic inflammatory diseases. The beneficial effects of sulphurous mineral waters, sulphurous mud, or peloids made from sulphurous mineral water have been attributed to the presence of sulphur mainly in the form of hydrogen sulphide. This form is largely available in conditions of low pH when oxygen concentrations are also low. In the organism, small amounts of hydrogen sulphide are produced by some cells where they have numerous biological signalling functions. While high levels of hydrogen sulphide are extremely toxic, enzymes in the body are capable of detoxifying it by oxidation to harmless sulphate. Hence, low levels of hydrogen sulphide may be tolerated indefinitely. In this paper, we review the chemistry and actions of hydrogen sulphide in sulphurous mineral waters and its natural role in body physiology. This is followed by an update of available data on the impacts of exogenous hydrogen sulphide on the skin and internal cells and organs including new therapeutic possibilities of sulphurous mineral waters and their peloids.

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Section: Topical Transformations and Hazardsmentioning

confidence: 99%

Sulphurous Mineral Waters: New Applications for Health

Carbajo

Maraver

2017

Evidence-Based Complementary and Alternative Medicine

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“…Hydrogen sulphide (H 2 S) waters are applied mostly in the form of baths defined as H 2 S or sulphur balneotherapy and indicated most frequently in the management of rheumatic diseases ) and a lesser extent in dermatological conditions Carbajo et al 2018a, b). Other balneological interventions with H 2 S-bearing water are as follows: drinking cure or hydropinic therapy (Scheidleder et al 2000;Costantino et al 2012), inhalations Carubbi et al 2019), irrigations ) and showers and sprays (Gálvez Galve et al 2012).…”

Section: Other Notes On Balneotherapymentioning

confidence: 99%

Nanominerals and Nanomaterials Utilized in Pharmacy and Therapeutics

Gomes

Santos

Amaral

2021

Minerals Latu Sensu and Human Health

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The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2021 This work is subject to copyright. All rights are solely and exclusively licensed by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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“…It can also act as a regulator of paracrine or autocrine. Sulfur‐based balneotherapy reduces the accumulation of leukocytes and Langerhans cells in the skin, elevates the β‐endorphins in the human skin, and reduces cytokine production (Boros et al, ; Gálvez Galve et al, ), significantly diminishing the PASI Score in psoriatic patients (Boros et al, ; Flisiak et al, ). Sulfurous water springs are scattered across Iran and are used by native people to treat many skin diseases, including psoriasis.…”

Section: Sulfurous Watermentioning

confidence: 99%

Use of mineral waters in the treatment of psoriasis: Perspectives of Persian and conventional medicine

Khalilzadeh

Shirbeigi

Naghizadeh

et al. 2019

Dermatologic Therapy

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Psoriasis is a chronic inflammatory disease, which is accompanied by social and emotional complications leading to considerable disability. There is no definitive cure and treatment options carry complications. Balneotherapy has been used for years in psoriasis. Antibiotic, keratolytic, and anti‐inflammatory effects of these waters have been proved. Persian medicine (PM) is a source of natural remedies for skin disease. The aim of study is to explain scientific evidences of Persian mineral waters as a treatment option for psoriasis. This is a narrative review, which investigates medical manuscripts of medieval Persia from 10th to 19th centuries AD noted as credible textbooks about mineral waters. Furthermore, balneotherapy evidences searched in databases including Pubmed, Scopus, and Cochrane until December 2017 to obtain clinical evidences related to psoriasis. In PM, mineral waters have keratolytic activity and can regulate superficial skin layers hyperproliferation, which is recommended for psoriasis treatment. In various studies, antiproliferative, keratolytic, antibiotic, anti‐inflammatory, and antioxidant effects of these waters have been proved completely. There are scientific evidences, which demonstrate that mineral waters in Persia, can reduce clinical symptoms of psoriasis and improve quality of life in patients. Therefore, this method might be considered as treatment options for psoriasis.

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Quality of life and assessment after local application of sulphurous water in the home environment in patients with psoriasis vulgaris: A randomised placebo-controlled pilot study

Cited by 16 publications

References 14 publications

Sulphurous Mineral Waters: New Applications for Health

Sulphurous Mineral Waters: New Applications for Health

Nanominerals and Nanomaterials Utilized in Pharmacy and Therapeutics

Use of mineral waters in the treatment of psoriasis: Perspectives of Persian and conventional medicine

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