Quality of life and cardiorespiratory function in chronic heart failure: effects of 12 months' aerobic training.

Abstract

Objective-To examine the long-term benefits and safety of aerobic training in patients with chronic heart failure.

Exercise and Heart Failure

“…65 A nonrandomized, controlled trial of 30 men and women showed a trend toward improved QOL but significant improvement in exercise parameters. 96 In summary, there is limited research examining QOL in patients with HF who have participated in exercise training; however, the majority of the existing data support an improvement in QOL after training in this population. …”

“…Of the 20 studies on exercise training in patients with chronic HF listed in Table 3, 37,56 -62,74,86,89,90,96,132-138 most do not mention the presence of mitral regurgitation in their patient populations. 56,57,59,60,74,75,89,90,96,[132][133][134][135][136][137][138] Other studies specifically exclude patients with significant mitral regurgitation. 37,86 In 2 studies that included patients with mild to moderate mitral regurgitation, 54,61 no separate analysis of their outcome is provided.…”

Effects of a home-based exercise program on clinical outcomes in heart failure

“…[1][2][3][4] However, the effects of exercise training on clinical outcomes are not well identified. Moreover, only 3 studies to date have followed patients beyond 6 months, 3,5,6 leaving the role of exercise in HF unclear. 7 Most exercise studies on HF have focused on laboratory-based or outpatient programs where patients exercise under controlled conditions.…”

Fatiguing exercise initiated later in life reduces incidence of fibrillation and improves sleep quality in Drosophila

“…A previous study reported that flies with disrupted clocks/impaired circadian rhythms showed significantly increased mortality risk after short-term oxidative challenge (24 h of 100 % hyperoxia) in the middle age and/or older age groups (Krishnan et ala major risk factor for the development of cardiovascular disease and heart failure that contributes to increased cardiovascular mortality and morbidity in elderly humans (Scalia et al 2010). Endurance exercise has long been known to improve cardiac function and to benefit even patients who are already experiencing heart failure (Erbs et al 2010;Kavanagh et al 1996). Most of these studies on the effect of exercise training on cardiac aging have been based on epidemiological and cross-sectional studies, since longitudinal studies across the lifespan of humans are intricate.…”