Quality of life and hormones after sex reassignment surgery

Castellano, Elena; Crespi, Chiara; Dell’Aquila, Carlotta; Rosato, Rosalba; Catalano, Carolyn; Mineccia, Valentina; Motta, Giovanna; Botto, E.; Manieri, C.

doi:10.1007/s40618-015-0398-0

Cited by 42 publications

(75 citation statements)

References 57 publications

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“…A few previous studies have indicated that transgender individuals also experience lower quality of life than the general population [10–12], even after gender reassignment surgery [11]. Conversely, other studies have found no difference in quality of life or psychological functioning between transgender individuals and the general population [13–16]. A major shortcoming concerning all previous studies includes a low number of participants, and one previous study has followed patients prospectively with regards to quality of life [17].…”

Section: Introductionmentioning

confidence: 99%

Quality of life improves early after gender reassignment surgery in transgender women

et al. 2016

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BackgroundFew studies have examined the long-term quality of life (QoL) of individuals with gender dysphoria, or how it is affected by treatment. Our aim was to examine the QoL of transgender women undergoing gender reassignment surgery (GRS).MethodsWe performed a prospective cohort study on 190 patients undergoing male-to-female GRS at Karolinska University Hospital between 2003 and 2015. We used the Swedish version of the Short Form-36 Health Survey (SF-36), which measures QoL across eight domains. The questionnaire was distributed to patients pre-operatively, as well as 1, 3, and 5 years post-operatively. The results were compared between the different measure points, as well as between the study group and the general population.ResultsOn most dimensions of the SF-36 questionnaire, transgender women reported a lower QoL than the general population. The scores of SF-36 showed a non-significant trend to be lower 5 years post-GRS compared to pre-operatively, a decline consistent with that of the general population. Self-perceived health compared to 1 year previously rose in the first post-operative year, after which it declined.ConclusionsTo our knowledge, this is the largest prospective study to follow a group of transgender patients with regards to QoL over continuous temporal measure points. Our results show that transgender women generally have a lower QoL compared to the general population. GRS leads to an improvement in general well-being as a trend but over the long-term, QoL decreases slightly in line with that of the comparison group.Level of evidence: Level III, therapeutic study.

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Section: Introductionmentioning

confidence: 99%

Quality of life improves early after gender reassignment surgery in transgender women

et al. 2016

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“…Three studies were carried out in Spain [ 21 , 32 , 34 ], in France [ 22 , 23 , 66 ] and in Belgium [ 43 , 65 , 83 ]. Two studies were conducted in Italy [ 73 , 74 ], UK [ 69 , 70 ], the Netherlands [ 20 , 35 ] and Germany [ 31 , 55 ], whilst one study was carried out in Switzerland [ 81 ], one in Sweden [ 64 ] and one in Turkey [ 76 ]. With regard to non-European countries one study was from Brazil [ 56 ], one from China [ 54 ] and the remaining articles were from the USA ( n = 7).…”

Section: Resultsmentioning

confidence: 99%

“…The scale’s internal consistency values have been found to range between 0.65 and 0.93 [ 39 ]. This tool was employed by four studies within this review [ 34 , 56 , 73 , 74 ]. 5.…”

Section: Introductionmentioning

confidence: 99%

Quality of life of treatment-seeking transgender adults: A systematic review and meta-analysis

Nobili

Glazebrook

2018

Rev Endocr Metab Disord

134

100

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The study aims to systematically extract and analyse data about Quality of Life (QoL) in the transgender population. A systematic literature search and meta-analysis were conducted using the MEDLINE, EMBASE, PubMed, and PsycINFO databases, up to July 2017. Only English language quantitative studies, in adults, which reported the means for validated QoL measures were included. Random-effect meta-analysis was adopted to pool data and estimate the 95% Confidence Intervals (CI). From 94 potentially relevant articles, 29 studies were included within the review and data extraction for meta-analysis was available in 14 studies. The majority of the studies were cross-sectional, lacked controls and displayed moderate risk of bias. Findings from the systematic review suggested that transgender people display poor QoL, independent of the domain investigated. Pooling across studies showed that transgender people report poorer mental health QoL compared to the general population (−0.78, 95% CI = −1.08 to −0.48, 14 studies). However, meta-analysis in a subgroup of studies looking at QoL in participants who were exclusively post-CHT found no difference in mental health QoL between groups (−0.42, 95% CI = −1.15 to 0.31; 7 studies). There was insufficient data for a pre-treatment subgroup. Evidence suggests that transgender people have lower QoL than the general population. Some evidence suggests that QoL improves post-treatment. Better quality studies that include clearly defined transgender populations, divided by stage of gender affirming treatment and with appropriate matched control groups are needed to draw firmer conclusions.

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“…Some evidence exists to support the view that this is not a theoretical claim. As it was examined, in some cases the levels of psychopathology, depression and psychiatric disorders, as well as quality of life and quality of body image scores of trans people after transitioning, reach values comparable to those of cis people (Dhejne et al, 2016;Olson et al, 2016;Castellano et al, 2015;Heylens et al 2014;de Vries et al, 2014). Unfortunately, however, this is not a universal pattern as trans people experience unique exclusions due to transphobia, which challenges their well-being (Reisner et al, 2016;White Hughto et al, 2015).…”

Section: Social Support For Trans Peoplementioning

confidence: 98%

“…In the literature studies found that transitioning can positively affect a person's life satisfaction through positive changes in appearance, attractiveness, body satisfaction, sex life, health-related quality of life, family and social relationships, partner relations, achievements in life, personal goals, self-confidence, identity and spirituality (van de Grift et al, 2017;Bockting et al, 2016;Costa and Colizzi, 2016;Köllen, 2016;Dhejne et al, 2016;White Hughto and Reisner, 2016;Cardoso da Silva et al, 2016;Schmidt, and Levine, 2015;Castellano et al, 2015;Ruppin and Pfäfflin, 2015;Brewster et al, 2014, Manieri et al, 2014Hess et al, 2014;Brewster et al, 2012, Salvador et al, 2012, Gorin-Lazard et al, 2012Colton-Meier et al, 2011;Johansson et al, 2010;Parola et al, 2010, Weyers et al, 2009Imbimbo et al, 2009;Nelson et al, 2009;Kraemer et al, 2008;Gijs, and Brewaeys, 2007;Lobato et al, 2006, De Cuypere et al, 2006, Smith et al, 2005Michel et al, 2002). 2013found that cross-sex hormonal treatment was linked to a better quality of life.…”

Section: Transitioning and Life Satisfactionmentioning

confidence: 99%

Trans People, Transitioning, Mental Health, Life, and Job Satisfaction

Drydakis

2020

Handbook of Labor, Human Resources and Population Economics

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For trans people (i.e. people whose gender is not the same as the sex they were assigned at birth) evidence suggests that transitioning (i.e. the steps a trans person may take to live in the gender with which they identify) positively affects positivity towards life, extraversion, ability to cope with stress, optimism about the future, self-reported health, social relations, self-esteem, body image, enjoyment of tasks, personal performance, job rewards and relations with colleagues. These relationships are found to be positively affected by gender affirmation and support from family members, peers, schools and workplaces, stigma prevention programmes, coping intervention strategies, socioeconomic conditions, anti-discrimination policies, and positive actions. Also important are legislation including the ability to change one's sex on government identification documents without having to undergo sex reassignment surgery, accessible and affordable transitioning resources, hormone therapy, surgical treatments, high-quality surgical techniques, adequate preparation and mental health support before and during transitioning, and proper followup care. Societal marginalization, family rejection, violations of human and political rights in health care, employment, housing and legal systems, gendered spaces, and internalization of stigma can negatively affect trans people's well-being and integration in societies. The present study highlights that although transitioning itself can bring well-being adjustments, a transphobic environment may result in adverse well-being outcomes. Policy makers should aim to facilitate transitioning and create cultures of inclusion in different settings, such as schools, workplaces, health services and justice.

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Quality of life and hormones after sex reassignment surgery

Abstract: This study highlights general satisfaction after SRS. In particular, transpeople’s QoL turns out to be similar to Italian matched controls. LH resulted inversely correlated to body image and sexual life scores.

Cited by 42 publications

References 57 publications

Quality of life improves early after gender reassignment surgery in transgender women

Quality of life improves early after gender reassignment surgery in transgender women

Quality of life of treatment-seeking transgender adults: A systematic review and meta-analysis

Trans People, Transitioning, Mental Health, Life, and Job Satisfaction

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