Quality of life and illness beliefs in individuals with early psychosis

Theodore, Kate; Johnson, Sonia; Chalmers-Brown, Anna; Doherty, R.; Harrop, Chris; Ellett, Lyn

doi:10.1007/s00127-011-0360-1

Cited by 28 publications

(21 citation statements)

References 35 publications

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“…9,44,45 In terms of the clinical correlates of QOL, as expected, a number of subjective domains were influenced by depressive symptoms, and objective domains were influenced by negative symptoms, which is consistent with FEP studies to date. 3,4,6,8,16,46 There were moderate correlations between some objective QOL domains and premorbid adjustment that were not retained as significant in regression models predicting objective QOL. Our finding that DUP independently predicts QOL is consistent with some studies, 4,16,47 but some have also found premorbid adjustment as an independent predictor.…”

Section: Discussionmentioning

confidence: 98%

Subjective and objective quality of life at first presentation with psychosis

Renwick

Drennan

Sheridan

et al. 2015

Early Intervention Psych

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We found that both subjective and objective assessments of QOL displayed a degree of clinical utility demonstrated by relationships between clinical factors and both QOL perspectives. Moreover, the lack of association between patient characteristics and QOL shows some potential malleability of QOL outcomes through intervention as there were several clinical factors linked with both subjective and objective QOL.

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Section: Discussionmentioning

confidence: 98%

Subjective and objective quality of life at first presentation with psychosis

Renwick

Drennan

Sheridan

et al. 2015

Early Intervention Psych

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“…17 In FEP patients, poor sQoL has been generally related to negative and depressive symptoms, longer duration of untreated psychosis (DUP), poor premorbid adjustment and certain illness beliefs (e.g. Browne et al; 3 Priebe et al; 17 Malla et al; 18 Theodore et al; 19 Gomez-de-Regil et al; 20 ). In order to better understand the factors related to the worsening of sQoL in early psychosis, it is important to examine which features are already associated with poor sQoL in individuals presenting clinical high risk.…”

Section: Introductionmentioning

confidence: 99%

Subjective quality of life in At‐Risk Mental State for psychosis patients: relationship with symptom severity and functional impairment

Domínguez-Mártínez

Kwapil

Barrantes‐Vidal

2013

Early Intervention Psych

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Findings indicate that different domains of sQoL are differentially and meaningfully associated with symptom severity and functional impairment, suggesting that greater symptom severity and poor functioning are already related with decreased sQoL in the ARMS for psychosis stage. Furthermore, findings highlight the importance of examining functional impairment and affective-motivational symptoms in future research on sQoL in ARMS populations due to their strong relationship with poor sQoL. Finally, findings underscore the importance of addressing the social and occupational dysfunctions already present in early psychosis with psychosocial interventions.

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“…Although literature demonstrated that anxiety symptoms (Huppert and Smith, 2001;Braga et al, 2005), especially social anxiety (Pallanti et al, 2004;Kumazaki et al, 2012) which is the most prevalent comorbid anxiety condition in patients with psychotic disorders (Achim et al, 2011), were related to poorer SQoL in chronic schizophrenia, very few studies have been conducted to investigate the association between anxiety symptoms (and none for social anxiety) and SQoL in FEP. Further, most of these first-episode studies assessed anxiety symptoms by using either ratings of a single item (Theodore et al, 2012) or a symptom component score combining depression and anxiety items (Priebe et al, 2000;Melle et al, 2005;Gorna et al, 2008;MacBeth et al, 2015) selected from a general psychopathology scale. Such measurement lacks specificity to detect the influence of anxiety symptoms, in particular social anxiety, on SQoL.…”

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confidence: 99%

Clinical and treatment-related determinants of subjective quality of life in patients with first-episode psychosis

Kwong

Chang

Chan

et al. 2017

Psychiatry Research

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Subjective quality of life (SQoL) has been increasingly studied in first-episode psychosis (FEP). Prior research primarily examined the impact of psychiatric symptoms on SQoL. Relationship between treatment-related factors and SQoL is under-studied. In this study, 159 Chinese patients who had completed 2-year treatment from early intervention service in Hong Kong were recruited. Assessments on premorbid adjustment, clinical profiles including social anxiety measure, functioning, antipsychotic-induced extrapyramidal side-effects and attitude toward medication treatment were conducted. SQoL was evaluated by Chinese version SF36 which generated mental and physical component summary (MCS and PCS) scores for analysis. Our results showed that more severe positive symptoms, higher level of depression, greater social anxiety, more negative attitude toward antipsychotic medications and greater degree of akathisia independently predicted lower MCS score. Higher social anxiety level and poorer functioning predicted lower PCS score. Our results indicate that affective and positive symptoms, functioning, and treatment-related variables are critical determinants of SQoL in FEP patients. These identified factors thus represent potentially malleable therapeutic targets for early detection and prompt intervention to promote enhancement of SQoL in the early stage of illness.

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Quality of life and illness beliefs in individuals with early psychosis

Cited by 28 publications

References 35 publications

Subjective and objective quality of life at first presentation with psychosis

Subjective and objective quality of life at first presentation with psychosis

Subjective quality of life in At‐Risk Mental State for psychosis patients: relationship with symptom severity and functional impairment

Clinical and treatment-related determinants of subjective quality of life in patients with first-episode psychosis

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