Quality of life and psychosocial situation before and after a lung, liver or an allogeneic bone marrow transplant

Goetzmann, Lutz; Klaghofer, Richard; Wagner-Huber, Regula; Boehler, Annette; Muellhaupt, Beat; Schanz, Urs; Buddeberg, Claus

doi:10.4414/smw.2006.11362

Cited by 7 publications

(2 citation statements)

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“…Indeed, a Swiss study found that following transplantation (for lung, liver, and bone marrow recipients), patients generally experienced an improved quality of life, life satisfaction, and psychological symptoms; however, the psychological wellness of liver transplant recipients worsened between 6 and 12 months after transplant. (43) Transplant communities could potentially address anxiety and other mental health issues in their patients by arranging for counseling both before and after transplant as well as more social work support.…”

Section: Original Article | 1629mentioning

confidence: 99%

Cannabinoid Use Among Liver Transplant Recipients

Yan

Forman

2021

Liver Transpl.

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The effect of cannabinoids on liver transplant outcomes is an area of active research. We aimed to investigate marijuana (MJ) and cannabidiol (CBD) use among liver transplant recipients at the University of Colorado Hospital (UCH), specifically prevalence, habits, and predictors of use. Liver transplant recipients followed at UCH with valid email addresses were sent an informed consent postcard and survey invitation. This exploratory survey was conducted using REDCap. IBM SPSS Statistics software was used for statistical analysis. Of 1227 recipients who were sent surveys, 538 people responded. On average, respondents were 59 years old, with 63.7% male and 81.7% White. Hepatitis C virus (HCV; 30.4%) and alcohol use (17.7%) were the most common etiologies of liver disease. Among respondents, 23.8% reported current MJ use. Methods of use included smoking (72.4%), ingestion (55.3%), and vaporization (31.7%). Top reasons for MJ use were recreation (56.5%), anxiety (54.8%), and pain (53.2%). Among respondents, 21.0% currently used CBD, usually in the form of creams or lotions (58.9%) and to relieve pain (84.9%) and anxiety (31.1%). In multivariable analysis, age (odds ratio [OR], 0.941; 95% confidence interval [CI], 0.923-0.959; P < 0.001), diabetes mellitus (OR, 0.357; 95% CI, 0.171-0.746; P = 0.01), HCV cirrhosis (OR, 3.949; 95% CI, 2.281-6.835; P < 0.001), alcohol-related cirrhosis (OR, 2.101; 95% CI, 1.202-3.671; P = 0.01), and current tobacco use (OR, 2.918; 95% CI, 1.065-7.990; P = 0.04) were significant predictors of MJ use. Our study shows that cannabinoid use after liver transplant is common. MJ use is associated with decreasing age, alcohol-related and HCV cirrhosis, and tobacco use. Anxiety, pain, and recreation were top reasons for its use. Transplant teams should address reasons why their patients use MJ and CBD and develop programs to mitigate anxiety and pain after transplant. Further studies are needed to examine effects of cannabinoids on liver transplant outcomes.

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Section: Original Article | 1629mentioning

confidence: 99%

Cannabinoid Use Among Liver Transplant Recipients

Yan

Forman

2021

Liver Transpl.

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“…A large number of prospective long-term studies have shown that quality of life after a heart, lung, liver or kidney transplant improves significantly and remains stable over a fairly long period of time [1][2][3][4][5][6][7][8][9][10]. Although attitudes play an important role in the processing of chronic diseases or the acceptance of medical interventions [11][12][13], attitudes towards the transplant have previously been investigated primarily in connection with organ donation or the carrying of an organ-donor ID card [14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Attitudes towards transplantation and medication among 121 heart, lung, liver and kidney recipients and their spouses

et al. 2012

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Lungentransplantation - wann muss in der Praxisdaran gedacht werden?

Höfer¹,

Boehler

2011

Therapeutische Umschau

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To date, lung transplantation is an established therapeutic modality for advanced lung disease. Post-transplant survival is excellent, but depends on sophisticated medical follow-up and treatment by a dedicated and experienced multidisciplinary lung transplant team. Transplantation leads to markedly improved quality of life. Medical complications after lung transplantation are frequent, such as infections (viral, bacterial and fungal), gastro-esophageal reflux, osteoporosis and chronic rejection. Prevention of these complications is crucial and lifelong adherence to therapy is warranted. The most important hurdle in transplantation medicine to date is the marked shortage of donor organs making it impossible to transplant all patients in need. Living donation and ex vivo reconditioning of marginal lungs might bring some relief.

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Quality of life and psychosocial situation before and after a lung, liver or an allogeneic bone marrow transplant

Cited by 7 publications

References 0 publications

Cannabinoid Use Among Liver Transplant Recipients

Cannabinoid Use Among Liver Transplant Recipients

Attitudes towards transplantation and medication among 121 heart, lung, liver and kidney recipients and their spouses

Lungentransplantation - wann muss in der Praxisdaran gedacht werden?

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