Quality of life and relationship satisfaction of patients with Obsessive Compulsive Disorder

Remmerswaal, Karin C.P.; Batelaan, Neeltje M.; Smit, Johannes H.; Oppen, Patricia van; Balkom, A.J.L.M. van

doi:10.1016/j.jocrd.2016.08.005

Cited by 23 publications

(13 citation statements)

References 66 publications

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“…The second hypothesis dealt with the impact of quality of life on marital satisfaction. This hypothesis was also confirmed, which is in line with the findings reported by Harju and Rentanin (32), as well as 33.Remmerswaa and Batelaan (33). Quality of life is one of the components of positive psychology, which includes perception, cognition, happiness, interests, expectations, and positive and negative emotions.…”

Section: Discussionsupporting

confidence: 90%

Relationship of Religious Orientation and Sense of Humor with Marital Satisfaction with the Mediation of Quality of Life among Women with Breast Cancer

Karami

Heidarisharaf

Kamari

et al. 2018

Health Spiritual Med Ethics

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ancer is one of the chronic and noncommunicable diseases that includes a wide range of problems. This disease, like all other chronic illnesses, can occur in any individual, age group, and race, and is considered as a problem affecting the health of the community (1). Cancer is the second leading cause of mortality in the developed countries behind cardiovascular diseases. In the less developed countries, this disease is the third most common cause of death preceded by cardiovascular diseases and accidents (2). Breast cancer has a significant impact on the stability of couples' and families' relationships because it directly involves the sexual identity of the women. Accordingly, the diagnosis of breast cancer is followed by turbulence in the individual's family and personal life, in addition to the physical problems and manifestations. Marital satisfaction is one of the factors that is seriously affected by this disease (3). Marital satisfaction is referred to a condition in which the husband and wife often feel happy and satisfied with their marriage (4), which can vary from high satisfaction to high dissatisfaction (5). Marital satisfaction is a personal experience that can be subjectively evaluated by each spouse based on the perceived pleasure of their marital relationship. This feeling plays an important role in the normal functioning of the family and is affected by many factors (6). Couples with high perceived marital satisfaction have a great C

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Section: Discussionsupporting

confidence: 90%

Relationship of Religious Orientation and Sense of Humor with Marital Satisfaction with the Mediation of Quality of Life among Women with Breast Cancer

Karami

Heidarisharaf

Kamari

et al. 2018

Health Spiritual Med Ethics

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“…Obsessive-compulsive disorder (OCD) has a lifetime prevalence of 2-3% [1,2] and results in reduced quality of life [3,4], lower educational attainment [5], suicidality [6,7], and even premature death [8,9]. A leading global cause of disability [10,11], OCD contributes to significant economic burden [12] that is expected to increase over the next 20 years [13].…”

Section: Introductionmentioning

confidence: 99%

Toward identifying reproducible brain signatures of obsessive-compulsive profiles: rationale and methods for a new global initiative

et al. 2020

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Background: Obsessive-compulsive disorder (OCD) has a lifetime prevalence of 2-3% and is a leading cause of global disability. Brain circuit abnormalities in individuals with OCD have been identified, but important knowledge gaps remain. The goal of the new global initiative described in this paper is to identify robust and reproducible brain signatures of measurable behaviors and clinical symptoms that are common in individuals with OCD. A global approach was chosen to accelerate discovery, to increase rigor and transparency, and to ensure generalizability of results. Methods: We will study 250 medication-free adults with OCD, 100 unaffected adult siblings of individuals with OCD, and 250 healthy control subjects at five expert research sites across five countries (Brazil, India, Netherlands, South Africa, and the U.S.). All participants will receive clinical evaluation, neurocognitive assessment, and magnetic resonance imaging (MRI). The imaging will examine multiple brain circuits hypothesized to underlie OCD behaviors, focusing on morphometry (T1-weighted MRI), structural connectivity (Diffusion Tensor Imaging), and functional connectivity (resting-state fMRI). In addition to analyzing each imaging modality separately, we will also use multi-modal fusion with machine learning statistical methods in an attempt to derive imaging signatures that distinguish individuals with OCD from unaffected siblings and healthy controls (Aim #1). Then we will examine how these imaging signatures link to behavioral performance on neurocognitive tasks that probe these same circuits as well as to clinical profiles (Aim #2). Finally, we will explore how specific environmental features (childhood trauma, socioeconomic status, and religiosity) moderate these brain-behavior associations.

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“…Severity of anxiety and depression symptoms were more important for QoL than unemployment and emotional instability in our study, which might indicate that feeling anxious or depressed overwhelms limitations caused by unemployment or emotional instability. In previous, cross-sectional studies, contradictory results were found on the effect of employment on QoL and the effect of emotional stability was not studied before [ 26 , 62 , 63 ]. Age, gender, and perceived lack of support were not associated with course of QoL in our study, contrasting results from previous cross-sectional studies [ 15 , 25 , 30 ].…”

Section: Discussionmentioning

confidence: 99%

“…Indeed, various longitudinal treatment studies indicate that OCD symptom reduction is not or only weakly related to QoL improvement [16,21,24] and to improvement of depressive symptoms [23]. Cross-sectional studies examining the factors associated with QoL in OCD report a variety of factors to impact on QoL in OCD patients, including older age, female sex, unemployment, contamination, hoarding and symmetry symptom dimensions, over-responsibility for harm, comorbid anxiety and depression symptoms, low social status, and perceived low social support [15,16,[25][26][27][28][29][30]. However, due to the cross-sectional design of these studies, causal inferences cannot be made.…”

Section: Introductionmentioning

confidence: 99%

Four-year course of quality of life and obsessive–compulsive disorder

Remmerswaal

Batelaan

Hoogendoorn

et al. 2019

Soc Psychiatry Psychiatr Epidemiol

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Objective Patients with obsessive compulsive disorder (OCD) have high disease burden. It is important to restore quality of life (QoL) in treatment, so that patients become able to live a fulfilling life. Little is known about the longitudinal course of QoL in patients with OCD, its association with remission from OCD, and about factors that contribute to an unfavourable course of QoL in remitting patients. Methods Study on the 4-year course of QoL of patients with chronic (n = 144), intermittent (n = 22), and remitting OCD (n = 73) using longitudinal data of the Netherlands Obsessive Compulsive Disorder Association (NOCDA; complete data: n = 239; imputed data n = 382). The EuroQol five-dimensional questionnaire (EQ-5D) utility score was used to assess QoL. In patients with remitting OCD, we examined patient characteristics that contributed to an unfavourable course of QoL, including sociodemographics, OCD characteristics, psychiatric comorbidity, and personality traits. Results Course of QoL was associated with course of OCD. QoL improved in those who remitted from OCD; however, even in these patients, QoL remained significantly below the population norms. The correlation between QoL and severity of OCD was only moderate: r = − 0.40 indicating that other factors besides OCD severity contribute to QoL. In remitters, more severe anxiety and depression symptoms were related to a lower QoL. Results were similar in complete and imputed data sets. Conclusions Remission from OCD is associated with improvement of QoL, but comorbid anxiety and depression symptoms hamper the improvement of QoL. QoL could be improved by reducing OCD symptoms in patients with OCD and by treating comorbid anxiety and depression symptoms in remitting patients.

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Quality of life and relationship satisfaction of patients with Obsessive Compulsive Disorder

Cited by 23 publications

References 66 publications

Relationship of Religious Orientation and Sense of Humor with Marital Satisfaction with the Mediation of Quality of Life among Women with Breast Cancer

Relationship of Religious Orientation and Sense of Humor with Marital Satisfaction with the Mediation of Quality of Life among Women with Breast Cancer

Toward identifying reproducible brain signatures of obsessive-compulsive profiles: rationale and methods for a new global initiative

Four-year course of quality of life and obsessive–compulsive disorder

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