The objective was to evaluate the effectiveness of ear acupuncture on quality of life and emotional disorders in nursing professionals during the COVID-19 pandemic. This was a clinical trial carried out with 179 professionals, who were randomized into two groups, namely: intervention, which received ear acupuncture, and control, which received no treatment. The Depression, Anxiety, and Stress Scale-21, the Event Impact Scale-Revised, and the World Health Organization Quality of Life-Bref were used. The analysis was carried out using Generalized Estimating Equations. Ear acupuncture improved quality of life and levels of stress, anxiety, and depression in the intervention group compared to the control group.