Quality of life and severity of skin and nail involvement in patients with plaque psoriasis

Abstract

A. Various colour gradations as a dermatoscopic feature of cutaneous angiosarcoma of the scalp. Australas J Dermatol 2013; 54: 36-8. 2. Cuperus E, Leguit R, Albregts M, Toonstra J. Post radiation skin tumors: basal cell carcinomas, squamous cell carcinomas and angiosarcomas. A review of this late effect of radiotherapy. Eur J Dermatol 2013; 23: 749-57. 3. Ulbright TM, Clark SA, Einhorn LH. Angiosarcoma associated with germ cell tumors. Hum Pathol 1985; 16: 268-72. 4. Kim MK, Huh SJ, Kim DY, et al. Secondary angiosarcoma following irradiation-case report and review of the literature. Radiat Med 1998; 16: 55-60. 5. Idrees MT, Kuhar M, Ulbright TM, et al. Clonal evidence for the progression of a testicular germ cell tumor to angiosarcoma. Hum Pathol 2010; 41: 139-44. 6. Contreras AL, Punar M, Tamboli P, et al. Mediastinal germ cell tumors with an angiosarcomatous component: a report of 12 cases.

Dermoscopic Features of Nail Psoriasis: An Observational, Analytical Study

“…Hallaji et al [24] reported significant correlation between total NAPSI and PASI in patients with plaque psoriasis. Van der Velden et al [16] reported no significant correlation between NAPSI and PASI, whereas Kyriakou et al [25] reported significant correlation (r = 0.515; p = 0.029). Wanniang et al [14] reported significant positive correlation between PASI and dermoscopic NAPSI scores (r = 0.34; p = 0.013).…”

The Impact of Nail Psoriasis and Treatment on Quality of Life: A Systematic Review

“…Across studies, psoriasis with nail involvement was associated with significantly higher baseline PASI scores [9][10][11][12][13][14][15]. Nail involvement was also associated with significantly greater QoL impairment [9][10][11][12][13][14][15]. In studies with subgroup analysis by gender, women had higher PASI and DLQI scores than men [10,12,13].…”

“…The mean age of subjects across studies was between 43.3 and 57.5 years [6,[9][10][11][12][13][14][15][16][17][18][19][20][21][22]. Composition of females in study samples also varied from 19.2 to 63.0% [6,[9][10][11][12][13][14][15][16][17][18][19][20][21][22]. The mean duration of psoriasis in those with nail involvement ranged from 11.5 to 34.3 years [6,[9][10][11][12][13][14][15][16][17][18][19][20][21][22].…”

“…Composition of females in study samples also varied from 19.2 to 63.0% [6,[9][10][11][12][13][14][15][16][17][18][19][20][21][22]. The mean duration of psoriasis in those with nail involvement ranged from 11.5 to 34.3 years [6,[9][10][11][12][13][14][15][16][17][18][19][20][21][22]. No studies included patients with comorbid onychomycosis.…”

“…Eight studies compared clinician-assessed severity and DLQI in patients with and without nail involvement (Table 1) [9][10][11][12][13][14][15]. Severity was reported by Psoriasis Area Severity Index (PASI) and Nail Psoriasis Severity Index (NAPSI).…”