Quality of life and unmet needs in patients with chronic liver disease: A mixed-method systematic review

Grønkjær, Lea Ladegaard; Lauridsen, Mette Munk

doi:10.1016/j.jhepr.2021.100370

Cited by 42 publications

(45 citation statements)

References 114 publications

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“…Such behavior may have been proposed from time to time as a critical factor to coping with a person affected with chronic illness. However, the literature in the context of this study is less endowed with descriptions, explanations, explorations, and predictions [ 22 , 23 ]. This empirical study intended to describe and explain the singularity.…”

Section: Introductionmentioning

confidence: 99%

Quality of Life among Caregivers of Patients Diagnosed with Major Chronic Disease during COVID-19 in Saudi Arabia

et al. 2022

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Quality of life (QoL) is considered one of the measures of health outcomes. Limited research studies have assessed family caregivers’ QoL, especially among patients diagnosed with chronic disease. This study measures the QoL of caregivers who guardian patients diagnosed with cardiovascular disease, diabetes, cancer, and/or other diseases during the COVID-19 pandemic. Participants were primary caregivers who were supporting, in the last six months, individuals diagnosed with one of the previously mentioned chronic diseases. This included caregivers of patients admitted to a tertiary hospital from January 2021 to July of the same year (n = 1081); all participants completed the World Health Organization Quality of Life Assessment tool (WHOQOL-BREF) questionnaire. Caregivers of patients with cancer reported the highest mean level of QoL, followed by diabetes, cardiovascular diseases, then other different diseases (M = 3.80; M = 3.38; M = 3.37; and M = 2.51, respectively). A chi-square test of independence was performed to examine the relationship between the QoL of the four groups and their behaviors (i.e., caregivers’ psychological onuses and physical actions/reactions). The relation between these variables was significant, X2 (3, n = 1081) = 8.9, p = 0.001. The Kruskal–Wallis test indicated significant differences among the four groups (p ≤ 0.001). While the overall results of the QoL level of participants were low, a major recommendation of this study was to incorporate a QoL assessment to caregivers of chronically ill patients. Regular psychological and physical health check-ups of caregivers should be mandated in the healthcare system. Research studies should consider investigating and identifying the factors affecting health outcomes and positive developments which have a great impact on the wellbeing of both caregivers and patients on personal, organizational, and national levels.

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Section: Introductionmentioning

confidence: 99%

Quality of Life among Caregivers of Patients Diagnosed with Major Chronic Disease during COVID-19 in Saudi Arabia

et al. 2022

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“…[1][2][3] Health-related quality of life (HRQOL), which reflects experiences, education, symptoms, satisfaction, and social and physical functioning, is often impaired in patients with CLD. 4 It is a common patient-reported outcome (PRO) and established measure in liver disease clinical trials. 5,6 Since integrating PRO in routine care for patients with CLD may improve patient care, 7 assessment of HRQOL as a PRO may be essential to good management of CLD.…”

Section: Introductionmentioning

confidence: 99%

Chronic liver disease questionnaire to manage patients with chronic liver diseases

Tajiri

Futsukaichi

Murayama

et al. 2022

Hepatology Research

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Background and Aims Although patients with chronic liver disease (CLD) usually show few symptoms, they exhibit decreased health‐related QOL (HRQOL) with occurrence complications including hepatocellular carcinoma (HCC). Health‐related QOL is an important indicator in the management of CLD. The Chronic Liver Disease Questionnaire (CLDQ) was established as a tool for assessment of HRQOL. In this study, we evaluate its usefulness for the management of daily clinical practice. Methods Patients (N = 190, median age 70 years old) treated between 2016 and 2019 were registered and prospectively followed‐up with annual CLDQ. Associations of liver function and development of factors for admission or death were evaluated. Results Of the 190 patients registered, median age 70 years old, 140 were Child‐A, 121 were Fib‐4 index >2.67 and showed 80 HCC. All 6 domains including Systemic Symptoms (SS) were negatively correlated with Child‐Pugh score more than with albumin‐bilirubin score and Fib‐4 index. A hundred four admission events and 49 deaths were found during observation period, and median event‐free survival was 34.3 months. Treatment for HCC was the most frequent cause of admission, and 37 liver‐related deaths were found. Systemic Symptoms score 2 years after registration was decreased in both HCC‐ and non‐HCC cohort. Systemic Symptoms decreased and SS < 4 might be predictive for event occurrence. Conclusions CLDQ is useful to assess HRQOL in patients with CLD and is well correlated with liver function especially Child‐Pugh. Chronic Liver Disease Questionnaire might be useful to predict the prognosis of CLD and can be a tool of management in clinical practice.

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“…These criteria are described in the methods section of the published review. 2 The mentioned studies by Zandi et al. 5 and Valery et al.…”

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confidence: 97%

“…We appreciate the comments made by Drs. Valery and Powell 1 with regard to our newly published mixed method systematic review 2 and we thank the Editors for given us the opportunity to respond.…”

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confidence: 99%

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Reply to: “Comment on “Quality of life and unmet needs in patients with chronic liver disease: A mixed-method systematic review””

Grønkjær

Lauridsen

2022

JHEP Reports

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Quality of life and unmet needs in patients with chronic liver disease: A mixed-method systematic review

Cited by 42 publications

References 114 publications

Quality of Life among Caregivers of Patients Diagnosed with Major Chronic Disease during COVID-19 in Saudi Arabia

Quality of Life among Caregivers of Patients Diagnosed with Major Chronic Disease during COVID-19 in Saudi Arabia

Chronic liver disease questionnaire to manage patients with chronic liver diseases

Reply to: “Comment on “Quality of life and unmet needs in patients with chronic liver disease: A mixed-method systematic review””

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