Quality‐of‐life aspects of the overactive bladder and the effect of treatment with tolterodine

Kobelt,; Kirchberger,; Malone-Lee,

doi:10.1046/j.1464-410x.1999.00004.x

Cited by 122 publications

(96 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Although comparable data on the lower urinary tract symptoms between patients with IDO and diabetic DO are not available, a recent large observational study reported on an increase in urge incontinence frequency in women with DM (12). This symptom has been shown to have a profound effect on patients' quality of life (13,14). Interestingly in our study, detrusor contractions occurred later during filling in the DM group than in patients with IDO.…”

Section: Discussionsupporting

confidence: 40%

Detrusor overactivity in diabetic and non-diabetic patients: is there a difference?

2012

View full text Add to dashboard Cite

ARTICLE INFO _________________________________________________________ ___________________Purpose: To compare urodynamic characteristics in patients with idiopathic detrusor overactivity (IDO) with those of an age matched cohort with diabetes mellitus (DM) and detrusor overactivity (DO). Secondly, to determine whether urodynamic features could help distinguish these two groups of patients. Materials and Methods: Urodynamic data was collected on 58 female patients; 29 with IDO and 29 with DM and detrusor overactivity. Eight urodynamic parameters were selected for analysis: amplitude of the first overactive contraction (AOFC), the volume at the first contraction, cystometric capacity, maximal detrusor pressure, maximal flow rate, voiding pressure at maximal flow, voided volume and postvoid residual (PVR) urine volume. Finally, sensitivity analysis for distinguishing urodynamic parameters between studied groups was performed. Results: AOFC, volume at AOFC and maximal detrusor pressure were statistically greater in diabetic patients, compared with the non-diabetic group of women (16.00 cm H 2 O versus 9.00 cm H 2 O, 309.00 mL versus 167.00 mL and 76.48 cm H 2 O versus 55.41 cm H 2 O respectively). A specificity of 72.41% and positive predictive value of 71.43% were achieved for AOFC with cutoff value of 12 cm H 2 O. These parameters were further improved with cutoff value of 258 mL for volume at AOFC and were 75.86% and 73.08% respectively. Conclusions: Certain urodynamic parameters in diabetic female patients with DO are shown to be significantly different than those in women with IDO. Further prospective study should provide additional information about the pathogenesis and progression of DO in diabetic patients as well as the validity of diabetic screening in patients with IDO.

show abstract

Section: Discussionsupporting

confidence: 40%

Detrusor overactivity in diabetic and non-diabetic patients: is there a difference?

2012

View full text Add to dashboard Cite

show abstract

“…This increase has resulted from the heightened awareness of the harmful effect of these symptoms on quality of life and from the limited range of current therapies for this condition. The subjective effect of OAB has been measured with the MOS ShortForm 36 generic quality of life instrument [3] . Studies showed that patients with bladder overactivity have significantly lower scores in most domains of this instrument than the normal population.…”

Section: Introductionmentioning

confidence: 99%

Incidence of Overactive Bladder after Vaginal Hysterectomy and Associated Repairs for Pelvic Organ Prolapse

Diez-Itza

Aizpitarte²,

Becerro³

et al. 2009

Gynecol Obstet Invest

View full text Add to dashboard Cite

Objective: The aim of this study was to determine the incidence of overactive bladder (OAB) after vaginal hysterectomy for pelvic organ prolapse (POP) and analyze the associated risk factors. Study Design: This was a retrospective cohort study of 217 patients who underwent primary POP vaginal surgery between the years 2000 and 2004 in Donostia Hospital and who did not report OAB before surgery. A personal interview was undertaken after surgery for the diagnosis of OAB, taking into account the ICS 2002 definition. Descriptive statistical analyses and multivariate logistic regression were performed to determine the factors associated with the development of OAB after POP surgery. Results: De novo OAB was diagnosed in 43 (19.8%) patients. The median time at onset of OAB symptoms after surgery was 3 months. Urge urinary incontinence was present in 28 patients (12.9%). Those women operated on also for stress urinary incontinence were at an increased risk for de novo OAB. Conclusion: Nearly 20% of women operated on for POP develop OAB soon after surgery. Those operated on for POP and stress urinary incontinence are more at risk.

show abstract

“…However, Professor Dowie seems sceptical as to the empirical evidence regarding the sensitivity of CSMs over generics. We agree there are cases that do not support this common claim in the psychometric literature [3], but equally there are many where this has been found including: EQ-5D in chronic pulmonary disease [4] and in cosmetic surgery [5], the SF-36 in urinary incontinence [6] and the example of urinary incontinence that he provides [7]. Copyright The main concern people have with generic measures is that their domains are too far removed from those of the patient and are often irrelevant to the condition.…”

mentioning

confidence: 85%

Measures of health‐related quality of life in an imperfect world: a comment on Dowie

Brazier

Fitzpatrick

2002

Health Economics

View full text Add to dashboard Cite

Quality‐of‐life aspects of the overactive bladder and the effect of treatment with tolterodine

Cited by 122 publications

References 31 publications

Detrusor overactivity in diabetic and non-diabetic patients: is there a difference?

Detrusor overactivity in diabetic and non-diabetic patients: is there a difference?

Incidence of Overactive Bladder after Vaginal Hysterectomy and Associated Repairs for Pelvic Organ Prolapse

Measures of health‐related quality of life in an imperfect world: a comment on Dowie

Contact Info

Product

Resources

About