Quality of Life Assessment by the Endometriosis Health Profile (EHP-30) Questionnaire Prior to Treatment for Ovarian Endometriosis in Brazilian Women

Abstract

Objective To evaluate the existence of an association between ultrasound findings and epidemiological and clinical factors using results obtained from the EHP-30 questionnaire in women with ovarian endometriosis. Methods A cross-sectional observational study was performed between July 2012 and May 2015, in which patients with chronic pelvic pain suggestive of endometrioma, as indicated by the results from a transvaginal pelvic ultrasonography, completed the standardized Endometriosis Health Profile -30 (EHP-30) questionnaire to access quality-of-life scores before beginning treatment for endometriosis. A total of 65 patients were included. The data was analyzed in the statistical program IBM SPSS Statistics for Windows, Version 22.0 (IBM Corp., Armonk, NY, USA) for the comparison of data through linear multiple regression. Results The suitability of the linear regression model was confirmed by the histogram of the dependent variable and the residue distribution plot, confirming the trend of linearity as well as the homogeneous dispersion of the residues. The mean age of the patients was 39.7 AE 7.1 years old. The majority was Caucasian (64.5%), had completed higher education (56.5%) and was nulligravida (40.3%). Infertility was present in 48.4% of the patients studied. Out of the total sample, 80.6% of the cases were symptomatic and complained mainly of acyclic pain, 79% of dysmenorrhea, and 61.3% of dyspareunia. This reflects the negative influence of endometriosis on the quality of life of patients with this disease. Conclusion Dyspareunia and acyclic pain were independent factors of correlation with high scores in the EHP-30 questionnaire, reflecting a worse quality of life.André Vinícius de Assis Florentino's ORCID is https://orcid.org/ 0000-0002-8005-3174.

Reductions in endometriosis-associated pain among women treated with elagolix are consistent across a range of baseline characteristics reflective of real-world patients

“…Many women with endometriosis experience a reduction in HRQoL [ 29 , 30 ]. Specifically, pelvic pain associated with endometriosis has been shown to negatively affect HRQoL [ 31 ].…”

A Cross-Sectional Study on the Quality of Life in Women with Endometrioma

“…Endometriosis is a chronic disease diminishing the QoL and requiring long-term care. 10,16 The most cited symptoms of endometriosis reported in our study were dysmenorrhea (97.0%), infertility (54.5%), and CPP (41.4%). In addition, the average pain score was relatively high (8.0 ±2.1) compared to previous reports.…”

Preditores de endometriose em mulheres atendidas em um Hospital Universitário

“…Em relação à escolaridade, a associação encontrada neste estudo diverge da literatura, que tem apontado que mulheres com alto nível de escolaridade possuem significativa maior frequência de diagnóstico de endometriose 13,18,26 . Essa discordância pode ser reflexo da população predominantemente atendida no hospital universitário, tendo em vista que apresenta o Sistema Único de Saúde como porta de entrada, favorecendo o atendimento a pessoas de menor nível socioeconômico.…”

“…Outras pesquisas confirmam a importante associação de dor pélvica com endometriose, como o realizado no ambulatório de dor, em São Paulo, em que a prevalência de endometriose entre as pacientes que se queixavam de dor acíclica foi de 80% 26 , e o realizado em um centro de cirurgia minimamente invasiva, no mesmo estado, que descreveu uma prevalência de 63% de endometriose nas mulheres que realizaram videolaparoscopia por dor pélvica crônica 19 . Um estudo de revisão sobre endometriose descreveu uma prevalência de 13% de sintomas urinários, no entanto, não detalhou se há ciclicidade na dor urinária 33 .…”