Quality of life changes in patients undergoing treatment for hepatocellular carcinoma

Abstract

There were significant differences in QoL deterioration across different treatment groups. This information may assist patients and providers when selecting patient-centered treatment approaches for HCC.

Factors related to the quality of life in liver cancer patients during treatment phase: A follow‐up study

“…Moreover, patients had greater deterioration of cognitive functioning when they underwent RFA versus TAE/TACE from baseline to 6 months. These results were consistent with the previous study (Chie et al, ; Eid et al, ). This might be because that the TAE/TACE was a palliative treatment for unresectable LC and it has the potential for serious liver toxicity due to ischaemia and reperfusion and retention of chemotherapeutic agents (Trevisani, De Notariis, Rossi, & Bernardi, ).…”

“…There were several studies that investigated the specific factors associated with QoL. Chie et al found that patients tended to have higher odds of QoL deterioration when treated with ablation versus embolisation or ablation versus surgery (Chie et al, 2015). Kolligs et al (2015) also found that selective internal radiation therapy (SIRT) had a similar impact on QoL as multiple sessions of transarterial chemoembolisation (TACE).…”

“…Previous studies mostly examined the effectiveness of different treatments in LC patients (Chie et al, 2015;Kolligs et al, 2015), and few studies explored the factors associated with QoL after treatments (Heits et al, 2015;Lai et al, 2007;Shomura et al, 2016;Shun et al, 2012). However, little is known about the changes in different dimensions of QoL and the specific factors associated with the changes in distinct dimensions of QoL from diagnosis to completed treatments.…”

Suicide rates among patients with cancers of the digestive system

“…To our knowledge, little research has examined suicide rates among US patients with esophageal and liver cancer, although each of these cancer types has an estimated 5‐year survival of less than 20% and may have quality‐of‐life concerns as a result of debilitating symptoms or treatment side effects . These cancers are also associated with alcohol and tobacco use, factors related to suicide risk in the general population .…”

Patient-Reported Outcomes After Extensive (Ultraradical) Surgery for Ovarian Cancer: Results From a Prospective Longitudinal Feasibility Study

“…For instance, Blazeby et al in 2012 and 2015 use this method of analysis in evaluating QoL after liver resection in colorectal cancer. 15,16 Morbidity Major morbidity and mortality were defined as intraoperative and postsurgical complications (9grade 2 according to the Memorial Sloan Kettering Cancer Center, MSKCC morbidity grading system) or death that occurred within 30 days after the surgical procedure. Major morbidity was divided into categories: infectious, gastrointestinal, cardiopulmonary, and thromboembolic complications.…”