Quality of life in a community sample of young cocaine and/or heroin users: the role of mental disorders

Chahua, Marcela; Sánchez-Niubò, Albert; Torrens, Marta; Sordo, Luis; Bravo, María J.; Brugal, M. Teresa; Domingo‐Salvany, Antònia

doi:10.1007/s11136-015-0943-5

Cited by 18 publications

(14 citation statements)

References 57 publications

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“…'nın psikiyatrik hastalığı olan bireylerin yaşam kalitesini etkileyen faktörleri inceledikleri başka bir çalışmada da eroin/kokain gibi madde kullanımının bireylerin yaşam kalitesi üzerinde anlamlı bir prediktör olduğu belirtilmektedir. 27 Costenbader ve ark. 'nın Hepatit C hastalarıyla yaptığı kesitsel çalışmada alkol, kokain, eroin gibi madde kullanımının yaşam kalitesi üzerine olumsuz etki ettiğini ifade etmişlerdir.…”

Section: Discussionunclassified

“…Literatür ile bu çalışmanın sonuçları paralellik göstermektedir. [26][27][28] Bu çalışmada sorun odaklı başa çıkma alanından aktif baş etme alt boyutunun inmeli bireylerin yaşam kalitesine olumsuz etki eden anlamlı bir prediktör olduğu bulundu. Literatür de baş etme tutumunu değerlendirmede kullanılan pek çok farklı ölçüm aracı bulunmaktadır.…”

Section: Discussionunclassified

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The Effect of The Coping Attitudes of People with Stroke on Quality of Life

Kes¹

2020

Ankara Med J

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Öz Amaç: İnme geçiren bireylerin hastalıkla başa çıkma tutumlarının yaşam kalitesi üzerine olan etkisini incelemektir. Materyal ve Metot: Tanımlayıcı türdeki bu çalışmanın örneklemini Ekim 2018-Haziran 2019 tarihlerinde inme sonrası kontrolleri için bir devlet ve bir eğitim araştırma hastanesinin nöroloji ve fizik tedavi polikliniğine gelen 360 birey oluşturdu. Verilerin toplanmasında sosyodemografik özellikler için oluşturulan anket formu, İnmeye Özgü Yaşam Kalitesi Ölçeği ve Başa Çıkma Tutumlarını Değerlendirme Ölçeği kullanıldı. İstatistiksel analizde SPSS 25.0 programı kullanıldı. Hastalıkla başa çıkma tutumlarının yaşam kalitesi üzerine olan etkisinin belirlenmesinde binary lojistik regresyon analizi kullanıldı. P<0,05 ve p<0,001 değerleri istatistiksel olarak anlamlı kabul edildi. Bulgular: Hastalıkla baş etme tutumlarından olan aktif başa çıkma (OR: 1,31 [95% CI 1,094-1,579]; p<0,05), geri durma (OR: 1,173 [1,022-1,347]; p<0,05), mizah (OR: 1,143 [1,023-1,276]; p<0,05) ve alkol/madde kullanımı (OR: 1,128 [1,008-1,262]; p<0,05)yaşam kalitesi üzerinde anlamlı prediktörler olduğu bulunmuştur. Sonuç: Aktif başa çıkma, geri durma, mizaç ve alkol/sigara kullanımı yaşam kalitesi üzerinde olumsuz etki eden faktörlör olup; bu faktörleri inmeli bireylerin yaşamında ne zaman ve ne sıklıkla kullandığı dikkatlice irdelenmeli ve hastanın başa çıkma tutumlarını ve yaşam kalitesini artıracak eğitim ve multidisipliner ekibin yer aldığı inme rehabilitasyon programlarının geliştirilmesi önerilmektedir. Anahtar Kelimeler: İnme, yaşam kalitesi, baş etme, COPE. AbstractObjectives: The aim of this study is to examine the effects of coping attitudes on quality of life in patient with stroke. Materials and Methods: This descriptive study was conducted between October 2018 and June 2019. The sample data were collected from 360 patients who had been admitted to neurology and physiotherapy clinics at a training and research university hospital and a government hospital in Karabuk. Data of the study were collected by the COPE inventory and the Stroke-Specific Quality of Life Scale. SPSS 25.0 program was used in the statistical analysis. Binary logistic regression analysis was used to determine the effect of coping attitudes on quality of life. P <0.05 and p <0.001 values were considered statistically significant. Results: Active coping (OR: 1.31 [95% CI 1.094-1.579]; p<0.05), restraint (OR: 1.173 [1.022-1.347]; p<0.05),humor(OR: 1.143 [1.023-1.276]; p<0.05) and alcohol/substance use(OR: 1.128 [1.008-1.262]; p<0.05), which are coping with the disease, were found to be significant predictors of on quality of life. Conclusion: Active coping, restraint, humor and alcohol / substance use are factors that negatively affect quality of life. When and how often these factors are used in stroke patients' lives should be examined carefully. it is recommended to develop stroke rehabilitation programs with training and multidisciplinary team to improve patient coping attitudes and quality of life.

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Section: Discussionunclassified

The Effect of The Coping Attitudes of People with Stroke on Quality of Life

Kes¹

2020

Ankara Med J

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“…Moreover, it would be difficult to find an adequate number of exposed individuals to allow sufficient statistical power for the study. Another limitation regards the lack of assessing information on psychiatric comorbidities, which are also associated with the quality of life of illicit drug users (Chahua et al., ).…”

Section: Discussionmentioning

confidence: 99%

“…The biological plausibility of the association between illicit drug use and oral health resides in the occurrence of xerostomia (Parry, Porter, Scully, Flint, & Parry, ), periodontitis (Antoniazzi et al., ; Casarin, Antoniazzi, Vaucher, Feldens, & Zanatta, ), unsatisfactory oral hygiene, and failure to seek dental care (Brown et al., ). The use of illicit substances exerts an impact on quality of life, especially among individuals with psychiatric comorbidities (Chahua et al., ). Considering their situation of living on the street or in treatment centers, such individuals likely feel inferior, which can further affect their quality of life.…”

Section: Introductionmentioning

confidence: 99%

The use of crack and other illicit drugs impacts oral health‐related quality of life in Brazilians

et al. 2017

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“…Dual diagnosis or co-occurring disorders describes the presence of both a mental health and a substance use disorder, and the dual nature of this condition complicates the diagnosis and therapeutic outcomes in CUD because many of the patients do not respond to classical pharmacological approaches ( Torrens, Gilchrist & Domingo-Salvany, the PsyCoBarcelona Group, 2011 ; Álvarez et al, 2013 ). Moreover, the quality of life of these patients is severely impaired ( Chahua et al, 2015 ).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of plasma cytokines in patients with cocaine use disorders in abstinence identifies transforming growth factor alpha (TGFα) as a potential biomarker of consumption and dual diagnosis

Maza-Quiroga

García-Marchena

Romero-Sanchiz

et al. 2017

PeerJ

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BackgroundCocaine use disorder (CUD) is a complex health condition, especially when it is accompanied by comorbid psychiatric disorders (dual diagnosis). Dual diagnosis is associated with difficulties in the stratification and treatment of patients. One of the major challenges in clinical practice of addiction psychiatry is the lack of objective biological markers that indicate the degree of consumption, severity of addiction, level of toxicity and response to treatment in patients with CUD. These potential biomarkers would be fundamental players in the diagnosis, stratification, prognosis and therapeutic orientation in addiction. Due to growing evidence of the involvement of the immune system in addiction and psychiatric disorders, we tested the hypothesis that patients with CUD in abstinence might have altered circulating levels of signaling proteins related to systemic inflammation.MethodsThe study was designed as a cross-sectional study of CUD treatment-seeking patients. These patients were recruited from outpatient programs in the province of Malaga (Spain). The study was performed with a total of 160 white Caucasian subjects, who were divided into the following groups: patients diagnosed with CUD in abstinence (N = 79, cocaine group) and matched control subjects (N = 81, control group). Participants were clinically evaluated with the diagnostic interview PRISM according to the DSM-IV-TR, and blood samples were collected for the determination of chemokine C-C motif ligand 11 (CCL11, eotaxin-1), interferon gamma (IFNγ), interleukin-4 (IL-4), interleukin-8 (IL-8), interleukin-17α (IL-17α), macrophage inflammatory protein 1α (MIP-1α) and transforming growth factor α (TGFα) levels in the plasma. Clinical and biochemical data were analyzed in order to find relationships between variables.ResultsWhile 57% of patients with CUD were diagnosed with dual diagnosis, approximately 73% of patients had other substance use disorders. Cocaine patients displayed greater cocaine symptom severity when they were diagnosed with psychiatric comorbidity. Regarding inflammatory factors, we observed significantly lower plasma levels of IL-17α (p < 0.001), MIP-1α (p < 0.001) and TGFα (p < 0.05) in the cocaine group compared with the levels in the control group. Finally, there was a significant primary effect of dual diagnosis on the plasma concentrations of TGFα (p < 0.05) in the cocaine group, and these levels were lower in patients with dual diagnosesDiscussionIL-17α, MIP-1α and TGFα levels are different between the cocaine and control groups, and TGFα levels facilitate the identification of patients with dual diagnosis. Because TGFα reduction is associated with enhanced responses to cocaine in preclinical models, we propose TGFα as a potential biomarker of complex CUD in humans.

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Quality of life in a community sample of young cocaine and/or heroin users: the role of mental disorders

Abstract: HRQoL among street-recruited illegal substance users was impaired, particularly among those with psychiatric comorbidity, psychosis, and BPD being especially relevant.

Cited by 18 publications

References 57 publications

The Effect of The Coping Attitudes of People with Stroke on Quality of Life

The Effect of The Coping Attitudes of People with Stroke on Quality of Life

The use of crack and other illicit drugs impacts oral health‐related quality of life in Brazilians

Evaluation of plasma cytokines in patients with cocaine use disorders in abstinence identifies transforming growth factor alpha (TGFα) as a potential biomarker of consumption and dual diagnosis

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