Quality of life in adult patients with acute myeloid leukemia receiving intensive and prolonged chemotherapy – a longitudinal study

Schumacher, Andrea; Keßler, Torsten; Büchner, Thomas; Wewers, Dieter; Loo, J. van de

doi:10.1038/sj.leu.2400977

Cited by 55 publications

(33 citation statements)

References 16 publications

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“…In addition, there was considerable patient heterogeneity concerning diagnosis (chronic myeloid leukemia at least 10 years after SCT) 37 , age (mainly children), 38 time of evaluation (at least 1 year after treatment) 39,40 and sample size. [4][5][6][7][8][9][10][11][12] Furthermore, a variety of different scales and self-made questionnaires were used. 4,6,7,10 The cross-sectional QOL study of the MRC AML 10 trial 16,17 used the EORTC QLQ-C30 score and further questions concerning sexual health and infertility in 479 patients, comparing the effects of allogeneic SCT, autologous SCT, and CCT, at least 1 year after consolidation treatment.…”

Section: Discussionmentioning

confidence: 99%

“…2,3 Assessment of quality of life (QOL) and late effects after completion of anti-leukemic treatment has increasingly become a focus of research. [4][5][6][7][8][9][10][11][12][13][14][15][16][17] Measurement of QOL shortly after diagnosis and during the course of conventional chemotherapy (CCT) showed that QOL improved steadily over time, paralleling the normalization of bone marrow function. 11 After completion of treatment, physical, psychological, and emotional well-being appeared to recover to almost normal levels.…”

Section: Introductionmentioning

confidence: 99%

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Impact of different post-remission strategies on quality of life in patients with acute myeloid leukemia

Messerer¹,

Engel²,

Hasford³

et al. 2008

Haematologica

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Impact of different post-remission strategies on quality of life in patients with acute myeloid leukemia

Messerer¹,

Engel²,

Hasford³

et al. 2008

Haematologica

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“…The provision of chemotherapy and acute leukemia patients experiencing high levels of side effects along with diverse morbidity may constitute a risk of prolonged bed rest 21, 34, 35. The present RCT advocates for systematic introduction of patient education, led by a clinical nurse specialist on the use of spirometry and PEP flute training 2‐4 times a day, especially during induction chemotherapy.…”

Section: Discussionmentioning

confidence: 95%

Early warning and prevention of pneumonia in acute leukemia by patient education, spirometry, and positive expiratory pressure: A randomized controlled trial

et al. 2016

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Long‐lasting neutropenia associated with acute myeloid leukemia (AML) and its treatment gives rise to a high risk of pneumonia. The use of broad‐spectrum antibiotic prophylaxis during outpatient management has not completely protected patients against admission due to infections and neutropenic fever, emphasizing the need to approach infection protection with complementary efforts. In a randomized controlled design, we examined the applicability of patient‐performed daily spirometry [forced expiratory volume in one second (FEV1)] as an early warning tool and explored the effectiveness of positive expiratory pressure (PEP) in preventing pneumonia among 80 AML patients. Twenty‐five incidences of pneumonia were detected among 23 patients (6 interventions, 17 controls), giving a prevalence of 28.75% during 5420 days of observation. We found a significant difference in incidence between intervention versus control group (2.17 per 1000 days vs. 6.52 per 1000 days, P = 0.021, respectively). A cross point at 80‐76% of the personal FEV1 reference value showed high sensitivity and specificity on pneumonia development. Our data demonstrate the feasibility of educating AML patients in their continuous daily measurement of FEV1 and use of PEP. Daily measures of FEV1 may be an important early warning tool for assessment of pulmonary deterioration during critical phases of neutropenia. We suggest that strategic patient education in the use of spirometry and PEP should be part of standard of care for AML patients undergoing induction chemotherapy. Am. J. Hematol. 91:271–276, 2016. © 2015 The Authors. American Journal of Hematology Published by Wiley Periodicals, Inc.

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“…Obejmuje ona takie obszary, jak: funkcjonowanie fizyczne, emocjonalne, społeczne oraz objawy choroby i skutki leczenia. Dodatkowo istotne w ocenie, poza objawami choroby i efektami ubocznymi leczenia, jest ujęcie postawy chorego wobec siebie, własnej choroby i sposób radzenia sobie [16][17][18][19]. Wprowadzenie pojęcia jakości życia do nauk medycznych doprowadziło do lepszej współpracy na linii lekarz-pacjent i odejścia od w pełni zależnej i podległej roli chorego wobec personelu medycznego.…”

Section: Jakość żYcia W Chorobie Nowotworowejunclassified

When the oncological patient gives support

Jakitowicz¹,

Bidzan²

2016

psy

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StreszczenieWstęp: W procesie radzenia sobie z chorobą onkologiczną istotną rolę odgrywa wsparcie społeczne. Celem prezentowanego badania jest określenie znaczenia wsparcia, jakie pacjent daje swoim bliskim, i jaki ma ono związek z radzeniem sobie z chorobą onkologiczną oraz jakością życia. Materiał i metody: W badaniu wzięło udział 35 pacjentów powyżej 18. roku ży-cia (18 kobiet i 17 mężczyzn) z chorobą nowotworową krwi, leczonych chemioterapią i poddanych transplantacji szpiku kostnego. Badanie przeprowadzono metodą kwestionariuszową z wykorzystaniem: autorskiego kwestionariusza wsparcia otrzymywanego i dawanego, zarówno emocjonalnego, jak i instrumentalnego, Skali przystosowania psychicznego do choroby nowotworowejMini-MAC w adaptacji Z. Juczyńskiego oraz Drabiny Cantrila. Wyniki: Prezentowane badanie ukazuje korzystny obraz mechanizmu wsparcia dawanego innym w kontekście choroby nowotworowej. Wykazano istotny zwią-zek wsparcia dawanego z destruktywnymi strategiami radzenia sobie, a nie wykazano związku ze strategiami konstruktywnymi. Wyniki jakości życia wskazują na pewną niespójność. W kontekście pracy psychologicznej z pacjentami chorymi onkologicznie warto uwzględnić rolę, jaką odgrywa wsparcie, które chory daje swoim bliskim. AbstractIntroduction: In the process of coping with the oncological disease important role is played by social support. The aim of this study is to determine the importance of the role of the social support offered by the patient. Material and methods: The study included 35 patients over 18 years of age (18 women and 17 men), suffering from the blood cancer, receiving chemotherapy and treated with bone marrow transplantation. The study was conducted using the questionnaire method with the following questionnaires: author's questionnaire received and given support, both emotional and instrumental, Mental Scale Adjustment to Cancer Diseases -Mini-MAC in adaptation Z. Juczyński and Cantril Ladder.Results: The present study shows a favorable picture of the given support mechanism in the context of cancer. Given support is significantly associated with a destructive coping strategies, and it was no connection with constructive strategies. The results of the quality of life show some inconsistency. In the context of psychological work with oncological patients given support should be taken into account, the role played by the patients who give support their relatives is significantly important.

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Quality of life in adult patients with acute myeloid leukemia receiving intensive and prolonged chemotherapy – a longitudinal study

Cited by 55 publications

References 16 publications

Impact of different post-remission strategies on quality of life in patients with acute myeloid leukemia

Impact of different post-remission strategies on quality of life in patients with acute myeloid leukemia

Early warning and prevention of pneumonia in acute leukemia by patient education, spirometry, and positive expiratory pressure: A randomized controlled trial

When the oncological patient gives support

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