Quality of life in adults with repaired tetralogy of Fallot

Abstract

IntroductionObservations of patients after repair of tetralogy of Fallot (ToF) indicate good correction results and long-term survival. Few papers have been published in which the quality of life (QoL) of this population has been assessed.AimTo evaluate QoL in adults with repaired ToF. Material and methodsWe included 39 patients with repaired ToF and 40 age- and sex-matched healthy volunteers. Information recorded included echocardiography, cardiac magnetic resonance, cardiopulmonary exercise test, and self-reported health-related QoL questionnaire (SF-36). ResultsThe perceived physical and mental domains of health were signi cantly poorer in ToF patients than in controls. A positive correlation between VO2 peak and physical domains was observed: (VO2 peak vs. physical domains (r = 0.6, p ≤ 0.001), general health (r = 0.36, p = 0.03), and physical complex status (r = 0.51, p = 0.001). VO2 peak % correlated with physical functioning (r = 0.43, p = 0.007), general health (r = 0.39, p = 0.015) and physical complex status (r = 0.49, p = 0.002). Right ventricle ejection fraction, determined with cardiac magnetic resonance, positively correlated with role physical (r = 0.38, p = 0.04). In echocardiography, pressure half time was posi- tively correlated with physical functioning (r = 0.48, p = 0.004) and role physical (r = 0.4, p = 0.02). ConclusionsThe QoL in adults after repair of ToF and healthy control subjects was compared directly. The self-perceived physical and mental domains of health were significantly poorer in ToF patients than in controls. Strong associations were found between objective exercise capacity and physical aspects of quality of life. Complex assessment and quality of life instruments should be used together to obtain an accurate view of health status of patients with repaired ToF.

A case report on Terotoloy of fallot

“…Nevertheless, TOF form during majority carries an advanced threat of developing arrhythmias, heart failure, and unforeseen cardiac arrest ( 18) . The advanced mortality in grown-ups than the paediatric group is caused by prolonged cardiac dysfunction and pulmonary roadway poor development, performing in long-standing cyanosis affecting the quality of life (19,20) . The physical health status isn't the only one affected by the delayed intervention.…”

“…The physical health status isn't the only one affected by the delayed intervention. Grown-ups with TOF who passed a form procedure tend to have significantly poor internal health (20) . The cerebral effect interferes with diurnal life conditioning, but it also majorly influences the treatment plan.…”

An Adult Patient With a Tetralogy of Fallot Case

“…Nonetheless, ToF repair during adulthood carries a higher risk of developing arrhythmias, heart failure, and sudden cardiac arrest [ 16 ]. The higher mortality in adults than the pediatric group is caused by prolonged RV dysfunction and pulmonary artery poor development, resulting in long-standing cyanosis affecting the quality of life [ 17 , 18 ].…”

“…The physical health status is not the only one affected by the delayed intervention. Adults with ToF who underwent a repair procedure tend to have significantly poor mental health [ 18 ]. The psychological effect interferes with daily life activities, but it also majorly influences the treatment plan.…”

Quality of Life in Ugandan Children and Young Adults After Surgery for Congenital Heart Disease: Mixed Methods Approach

“…Even though the global birth rate of CHD has remained constant, advances in cardiac surgery have led to a decline in the death rate of those born with CHD by 60.4% in the last two decades [ 1 2 ]. As a result, adolescents and adults need life-long care for congenital heart conditions, and health-related quality of life (HRQOL) has emerged as a critically important issue in this population [ 3 4 5 6 7 8 9 ].…”