Quality of life in adults and older adults with Chagas disease

Ozaki, Yaeko; Dias, Ernesta Lopes Ferreira; Almeida, Eros Antônio de; Guariento, Maria Elena

doi:10.24220/2318-0897v24n3a2654

Cited by 5 publications

(7 citation statements)

References 23 publications

(42 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In a sample with several chronic forms of the disease (indeterminate, cardiac, and digestive), one study 24 showed no difference in HRQoL assessed using the WHOQOL-Bref between men and women. However, two other studies 8 , 23 that included a larger sample with the same chronic forms of the disease and used the same questionnaire showed different results. Ozaki et al 23 demonstrated that women had worse scores in the environment domain and were more likely to perceive worse HRQoL than men.…”

Section: Association Between Hrqol and Sociodemographic Or Lifestyle ...mentioning

confidence: 94%

“…However, two other studies 8 , 23 that included a larger sample with the same chronic forms of the disease and used the same questionnaire showed different results. Ozaki et al 23 demonstrated that women had worse scores in the environment domain and were more likely to perceive worse HRQoL than men. Santos-Filho et al 8 also demonstrated that women were independently associated with worse HRQoL in the overall score as well as in the physical and psychological domains of the WHOQOL-Bref.…”

Section: Association Between Hrqol and Sociodemographic Or Lifestyle ...mentioning

confidence: 94%

“…In a sample stratified among chronic forms of the disease (indeterminate, cardiac, and digestive forms), the presence of cardiovascular or digestive symptoms was associated with worse HRQoL in many domains (physical, psychological, and social relationships) of the WHOQOL-Bref 23 . Thus, it appears that cardiovascular and digestive symptoms are responsible for the poor HRQoL of patients with CD.…”

Section: Hrqol In Patients With Chagas Diseasementioning

confidence: 99%

See 2 more Smart Citations

The health-related quality of life in patients with Chagas disease: the state of the art

Almeida

Oliveira

Figueiredo

et al. 2022

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

Chagas disease (CD) is a neglected tropical disease associated with poverty in which patients are surrounded by stigma. These factors can contribute to reducing health-related quality of life (HRQoL). Therefore, a broad discussion of HRQoL in the CD population is required. This study aimed to discuss the main findings of HRQoL in patients with CD, focusing on the association between sociodemographic and lifestyle factors, echocardiographic and functional determinants, and the effect of non-invasive interventions on HRQoL. A literature search of the MEDLINE, Web of Science, CINAHL, Scopus, and LILACS databases was performed with no data or language restrictions. Twenty-two articles were included in this meta-analysis. In general, HRQoL is worse in patients with CD than in healthy individuals, particularly in the presence of cardiovascular and/or gastrointestinal symptoms. Sex, age, functional class, level of physical activity, healthy habits, and medications received could affect HRQoL. Among the echocardiographic and functional determinants, decreased systolic function seems to negatively affect HRQoL. No association with the peak oxygen uptake was observed in the maximal tests. By contrast, well-tolerated field tests with submaximal intensities were associated with HRQoL. Both pharmaceutical care and exercise training have a positive effect on the HRQoL of patients with Chagas cardiomyopathy, and the mental component can be a prognostic marker in this population. In conclusion, assessment of HRQoL can provide important information about the health status of patients with CD, and its use in clinical practice is warranted.

show abstract

Section: Association Between Hrqol and Sociodemographic Or Lifestyle ...mentioning

confidence: 94%

Section: Association Between Hrqol and Sociodemographic Or Lifestyle ...mentioning

confidence: 94%

Section: Hrqol In Patients With Chagas Diseasementioning

confidence: 99%

See 1 more Smart Citation

The health-related quality of life in patients with Chagas disease: the state of the art

Almeida

Oliveira

Figueiredo

et al. 2022

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

show abstract

“…A better female QoL was observed in studies involving patients with CD and other chronic diseases [35,44]. However, there are controversial results in that females were a predictor of worse QoL [7,9,26]. In the present study, a better perception of QoL in the Social Relations domain by women may be related to the fact that they have better social and interpersonal integration and also greater family involvement, which may favor their QoL [35], especially in this dimension.…”

Section: Plos Neglected Tropical Diseasesmentioning

confidence: 46%

“…Social Relations domain [9,26,27]. The lower QoL score in the Environment domain may be an impact marker of the social determinants of health on the individual perception of QoL.…”

Section: Plos Neglected Tropical Diseasesmentioning

confidence: 99%

Factors associated with quality of life in patients with Chagas disease: SaMi-Trop project

et al. 2020

View full text Add to dashboard Cite

Chagas disease (CD) is a neglected tropical disease and its main consequence is chronic chagasic cardiomyopathy (CCC). The clinical manifestations of CD can cause functional limitation and impact on the perception of quality of life (QoL). We evaluated the QoL profile of patients with CD living in remote regions, and their association with socio-demographic, behavioral, and clinical characteristics.A cross-sectional study, using the baseline of a cohort study (SaMi-Trop) was conducted in the state of Minas Gerais, Brazil, an endemic region for CD. The cohort is composed of 1959 patients with CD. The patients were interviewed, and blood collection and electrocardiogram (ECG) were performed. The WHO-QOL-BREF scale was used to assess QoL. Descriptive statistics were performed and, for the QoL scale, measures of central tendency and dispersion were calculated. Inflated beta regression models constructed using the gamlss framework were used, and fitted using R software. A significance level of 5% for all analyzes was adopted.QoL was evaluated in 625 participants. The Environment (57.66) and Social Relationships (73.17) domains presented the lowest and highest QoL score respectively. There was no statistically significant difference between QoL domains in the presence of CCC. In the multivariate analysis, the factors associated with a lower QoL were in the Physical domain age increase (OR: 0.95, CI: 0.91-0.99) and using an angiotensin converting enzyme inhibitor (OR 0.89; CI: 0.80-0.99); in the Social Relations domain a history of acute myocardial infarction (OR: 0.75; CI: 0.61-0.92); and in the Environment domain age increase (OR 0.94, CI 0.91-0.97). The factor associated with higher QoL was the use of angiotensin receptor blockers (OR: 1.15; CI 1.04-1.26).The findings of this study reinforce the importance of QoL indicators for planning care and clinical management of patients from remote regions with CD.

show abstract

The Association Between Physical Performance and Health-Related Quality of Life Based on the EQ-5D-3L Questionnaire in Patients With Chagas Disease

Lins

Tura²,

Kasal³

2021

Value in Health Regional Issues

View full text Add to dashboard Cite

Objectives: Chagas disease (CD) is a chronic disease to millions worldwide, and many patients develop heart disease. In addition, they are part of an aging population. These characteristics can be associated with a reduction in physical performance and health-related quality of life (HRQoL). This study evaluated HRQoL, and the relationship between physical performance and HRQoL in patients with chronic CD.Methods: We used the 3-level version of EQ-5D-3L, with the visual analog scale (VAS). Physical performance was measured with 30-s chair-stand test (30sCST) and timed up and go test (TUGT).Results: Sixty-three patients were evaluated. The majority were women (68.2%) aged 67.7 6 9.7 years. Overall EQ-5D-3L utility index was 0.65 6 0.28, and VAS score was 68.4 6 25.1. Most patients with intermediate and high performance in 30sCST referred no problems in the domains "mobility," "usual activities," and "pain/feeling ill" (P , .001, P = .01, and P = .025, respectively). In a similar way, most patients with intermediate and high performance in TUGT referred no problems in "mobility" (P , .0001) and "usual activities" (P = .001). Higher performance in both tests was associated with higher overall EQ-5D-3L utility and VAS scores. HRQoL measured by EQ-5D-3L was associated with physical status in a cohort of patients with chronic CD. The results underscore the contribution of physical performance, measured by 2 inexpensive and safe physical tests, to HRQoL in these patients. Conclusion:Strategies aiming the improvement of HRQoL in patients with CD may focus on mobility skills and force. Future studies evaluating interventions in physical performance should be a priority in these patients.

show abstract

Quality of life in adults and older adults with Chagas disease

Cited by 5 publications

References 23 publications

The health-related quality of life in patients with Chagas disease: the state of the art

The health-related quality of life in patients with Chagas disease: the state of the art

Factors associated with quality of life in patients with Chagas disease: SaMi-Trop project

The Association Between Physical Performance and Health-Related Quality of Life Based on the EQ-5D-3L Questionnaire in Patients With Chagas Disease

Contact Info

Product

Resources

About