Quality of Life in Dementia

Naglie, Gary

doi:10.1017/s0317167100005588

Cited by 30 publications

(26 citation statements)

References 61 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…If interventions are primarily dealing with health outcomes, then using patient rated QOL-AD is an appropriate method of incorporating patient perspectives into intervention decisions. Treatment interventions such as pharmacological agents are aimed at improving physical, behavioural, and psychological symptoms; one method to determine the efficacy of such treatments should be to include patient-rated QOL (Naglie, 2007).…”

Section: Discussionmentioning

confidence: 99%

Quality of life in early dementia: Comparison of rural patient and caregiver ratings at baseline and one year

et al. 2011

View full text Add to dashboard Cite

This study examined change in patient and caregiver ratings of patient quality of life (QOL) over one year in individuals with dementia living in rural and remote settings. The sample was selected from non-institutionalized patients who were assessed at an interprofessional memory clinic. Measures of QOL, cognitive function, depression, and functional ability were completed by the patient. Caregivers completed measures of patient QOL and behavior, and their own burden and distress. At baseline (clinic day) 119 patients and family caregivers were assessed. Thirty-two families had complete data at clinic day and one-year follow-up. There was no significant change in either patient or caregiver-rated QOL over one year. Significant predictors of patient self-rated QOL were patient symptoms of depressed mood and functional ability at clinic day, and symptoms of depressed mood and clinic day QOL at one year. Significant predictors of caregiver-rated patient QOL were caregiver burden, patient functional ability, and symptom severity at clinic day, and caregiver burden at one year. Patient and caregiver ratings of patient QOL were moderately

show abstract

Section: Discussionmentioning

confidence: 99%

Quality of life in early dementia: Comparison of rural patient and caregiver ratings at baseline and one year

et al. 2011

View full text Add to dashboard Cite

show abstract

“…It is widely agreed that the individuals themselves are the best source of information regarding internalized constructs such as health-related quality of life and preferences for care in various health conditions [5–9]. Evidence suggests that a large majority of people with mild to moderate cognitive impairment, and some with severe dementia, can provide meaningful insight into their quality of life and preferences for care [7, 10, 11]. However, a considerable proportion of patients who require medical decision-making are incapable of providing such insight [12, 13].…”

Section: Introductionmentioning

confidence: 99%

Reliability of health-related quality-of-life assessments made by older adults and significant others for health states of increasing cognitive impairment

Bravo

Sene

Arcand

2017

Health Qual Life Outcomes

View full text Add to dashboard Cite

BackgroundOlder adults are encouraged by many organizations to engage in advance care planning in the event of decisional incapacity. Planning for future health care often involves anticipating health-related quality of life (HRQoL) in states of reduced cognitive functioning. No study has yet examined whether anticipated HRQoL is stable over time. The accuracy with which significant others can predict how an older adult envisions HRQoL in a future state of cognitive impairment is also unknown. We investigated the extent to which health-related quality-of-life ratings made by older adults and designated proxies for health states of increasing cognitive impairment are consistent over time and agree with each other.MethodsResults are based on HRQoL ratings made on a 5-point Likert scale by 235 community-based elder-proxy dyads on three occasions. Ratings were obtained for the older adult’s current health state as well as under the assumption that he/she had a mild to moderate stroke, incurable brain cancer or severe dementia. Data were analyzed using both traditional approaches (e.g., intraclass correlation coefficients, Bland-Altman plots) and the theory of generalizability.ResultsWe found ratings to be reasonably consistent over time and in good agreement within dyads, even more so as implied cognitive functioning worsened. Across health states, ratings over time or within elder-proxy dyads were no more than one category apart in over 87% of cases. Using the theory of generalizability, we further found that, of the two facets investigated, rater had a greater influence on score variability than occasion.ConclusionsThese findings underscore the importance of discussing health-related quality-of-life issues during advance care planning and involving designated proxies in the discussion to enhance their understanding of the role that HRQoL should play in actual decision-making situations. Medical decision-making may be influenced by healthcare providers’ and family members’ assessments of an incapacitated patient’s health-related quality of life, in addition to that of the designated proxy. Future studies should investigate whether these two groups of individuals share the views of the patient and the designated proxy on anticipated HRQoL.Electronic supplementary materialThe online version of this article (doi:10.1186/s12955-016-0579-3) contains supplementary material, which is available to authorized users.

show abstract

“…Since 2001 the Group for Harmonization of Dementia Drug Guidelines and the Alzheimer's Society (Mack and Whitehouse, 2001) have recommended the evaluation of quality of life to verify the efficacy and appropriateness of therapeutic interventions, not only from the patient's perspective but also from that of family caregivers or professionals. However, research is still needed to clarify a number of key questions: which measures are the most valid and reliable for assessing QoL-p, what is the best type of administration (auto or rater-administrated questionnaire) according to the degree of cognitive impairment, who are the best informants, and which factors influence the perception of QoL-p in patients and other informants (Naglie, 2007).…”

Section: Introductionmentioning

confidence: 99%

Factors related to perceived quality of life in patients with Alzheimer's disease: the patient's perception compared with that of caregivers

Conde-Sala

Garré-Olmo

Turró‐Garriga

et al. 2008

Int J Geriat Psychiatry

139

169

View full text Add to dashboard Cite

Aims: To compare care recipient and caregiver perceptions of quality of life in patients (QoLp) with Alzheimer's disease (AD). To identify associated factors, and the concordancesdiscrepancies. Method:Cross-sectional analytic study of 236 patients and their carers using the Quality of Life in Alzheimer's Disease (QoL-AD) scale, socio-demographic data and clinical examination. Results:Patients scored the QoL-AD more favourably than did caregivers (34.4 vs. 31.3, p<0.001). Cognitive deterioration did not affect the perception of QoL-AD (rho= -0.05, p=0.394). The neuropsychiatric symptoms was associated with a negative perception of the QOL-AD in both patients (rho= -0.22, p<0.01) and caregivers (rho= -0.47, p <0.001). Greater functional autonomy was associated with a better perception of the QOL-AD in patients (rho= 0.17, p<0.01) and even more so in caregivers (rho= 0.56, p<0.001). In carers, burden (rho= -0.56, p<0.001) and mental health (rho= 0.31, p<0.001) were inversely associated with the QoL-AD. QoL-AD scores of both patients and caregivers were higher for men, married subjects, those who lived with their spouse and those living in their own home. When the carer was a spouse both patients and caregivers scored the QoL-AD higher than when the carer was a son or daughter (35.5 vs. 33.4 and 33.7; 32.9 vs. 30.5 and 27.7, p<0,001). Conclusions

show abstract

Quality of Life in Dementia

Cited by 30 publications

References 61 publications

Quality of life in early dementia: Comparison of rural patient and caregiver ratings at baseline and one year

Quality of life in early dementia: Comparison of rural patient and caregiver ratings at baseline and one year

Reliability of health-related quality-of-life assessments made by older adults and significant others for health states of increasing cognitive impairment

Factors related to perceived quality of life in patients with Alzheimer's disease: the patient's perception compared with that of caregivers

Contact Info

Product

Resources

About