Quality of life in epilepsy

Abstract

Background: The quality of life (QOL) evaluation is a relatively new measure to evaluate the outcome of epilepsy. Many factors influence the quality of life of people with epilepsy, including seizure severity, stigma, fear, and the presence of cognitive or psychiatric problems. QOL is influenced by biological factors as well as cultural, social and religious beliefs and values. This study was planned to find out the impact of epilepsy on quality of life of epileptic patients.Methods: The study was conducted in the epilepsy clinic of department of neurology at a tertiary care hospital over a period of one year.101 patients were included after fulfilling the inclusion criteria. All the patients seeking treatment in the OPD were screened, assessed and then all procedures were fully explained to them. History regarding name, age sex, socio-demographic profile and detailed history regarding seizure disorder was taken from both the patient and the reliable informant. Bengali version of QOLIE-9 was used to assess the quality of life.Results: One hundred and one patients with epilepsy consisting of 70 men (69.3%) and 31 women (30.7%) were included. Their ages ranged from 15 to 52, the mean age being 26.17 (SD = 7.84). Out of the 101 patients, 65 patients (64.4%) were suffering from partial epilepsies and 36 patients (35.6%) were suffering from generalized epilepsies. Mean QOLIE-9 total scores were 16.66, 19.74, 20.13 and 24.00 in married, widows, unmarried and separated individuals respectively. The differences in the means were statistically significant on ANOVA (p value 0.002). Mean QOLIE-9 total scores were 27.75, 19.64, 19.65, 18.14 and 18.00 in primary, secondary, higher secondary, graduate and postgraduate individuals respectively. The differences were highly significant statistically on ANOVA (p value<0.001). Frequency of seizures per month was positively correlated with QOLIE-9 total scores (Pearson Correlation 0.622) and was highly statistically significant (p value<0.001).Conclusions: Frequent seizures, lower education level and single status are associated with lower quality of life in persons with epilepsy.

Assessment of Quality of Life of Epileptic Patients in Ethiopia

“…ose who are unemployed get bored and face more cognitive problems. is nding is similar to the study done by Singh and Pandey [31] and Ashjazadeh et al [32]. Mean QOLIE-10 score of patients with household monthly income <22 USD was 21.4. e score is signi cantly higher (lower quality of life) than for patients who got 22 USD or more per month.…”

“…Patients who perceive their epilepsy status was controlled had better quality of life as had no formal education. is nding is supported by many other studies [16,[29][30][31]. e poor QoL observed in illiterate patients may be due to the lesser knowledge they may have about the diseases and its treatment; as well as they may not easily understand instructions given from health professionals and this may result in poor adherence to medication and poorer seizure control which may nally lead to poor quality of life.…”

“…is contrasting with the result of the studies conducted in Malaysia, Iran and China. [31][32][33]. Quality of life of unemployed patients is signi cantly lower than those of epileptic patients who have a job.…”

Quality of Life in Patients with Drug Resistant Epilepsy

“…This is in line with the results of various studies Marital status had a significant influence on all domains of QoL in the present study. These findings were consistent with the results of the study conducted by Singh et al (14) which showed that the mean QOLIE-9 total scores were 16.66, 19.74, 20.13, and 24.00 in married, widowed, unmarried, and separated individuals, respectively. The differences in the means were statistically significant in ANOVA (p=0.002).…”

“…The differences in the means were statistically significant in ANOVA (p=0.002). This implies that marriage confers a benefit to QoL (14). The marital relationship is an important constituent of family and provides social support and satisfaction, and failure to maintain marriage goes against social norms.…”