Quality of Life in Female Patients Following Ileal Neobladder and Ileal Conduit: Where Are We?

Siracusano, Salvatore; Zaka, Agustina; Romantini, Federico; Porcaro, Antonio Benito; Vicentini, Carlo; Lonardi, Cristina

doi:10.3390/jcm10143042

Cited by 9 publications

(5 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…When comparing the results of patients with incontinent and continent urinary diversions in our study cohort, no significant differences were found in the EORTC questionnaire. This is in accordance with the findings of several authors in the past who found no significant diversion-related differences regarding QoL [ 21 – 23 ], whereas other studies have shown better results for either incontinent [ 24 ] or continent [ 25 ] diversions. Therefore, whether the type of urinary diversion really influences the rates of sexual function and QoL remains unclear [ 7 , 21 ].…”

Section: Discussionsupporting

confidence: 93%

Evaluation of sexual function and vaginal prolapse after radical cystectomy in women: a study to explore an under-evaluated problem

et al. 2023

View full text Add to dashboard Cite

Introduction and hypothesis The objective was to evaluate sexual function, vaginal prolapse, and quality of life (QoL) in women after radical cystectomy (RC) using validated questionnaires and pelvic organ prolapse quantification (POP-Q) measurement. Methods Female bladder cancer patients who underwent RC at our tertiary care center were included (January 2008 to March 2022). Patients received three validated questionnaires (International Consultation on Incontinence Questionnaire Vaginal Symptoms [ICIQ-VS] Part A, Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire IUGA revised [PISQ], European Organization for Research and Treatment of Cancer Quality of Life Questionnaire [EORTC] C30/BLM30). Patients who consented were examined with vaginal POP-Q measurement. Results Out of 322 patients, 193 were still alive, 54 patients were lost to follow-up, and 43 were excluded, resulting in 96 patients who received the questionnaire. Finally, 35 patients were included, of whom 17 patients consented to vaginal examination. Complaints due to vaginal symptoms were low (ICIQ-VS 6.17 + 5.37). Sexual activity was reported by 12 patients (34.3%); 23 patients (65.71%) were not sexually active. No apical prolapse was found in POP-Q measurement; 6 patients (35.3%) had anterior, and 14 patients (82.4%) posterior prolapse; the highest prolapse stage was 2. No significant differences were found regarding POP stages, sexual function, and QoL (all p > 0.05) when comparing continent and incontinent urinary diversions. Comparing the vaginal approach (no sparing vs sparing), significant differences were found in only two PISQ subscales (significantly higher scores after vagina sparing, p = 0.01 and p = 0.02). Conclusions The type of urinary diversion, POP-Q stages, and tumor stages did not show significant differences regarding sexual function, QoL, and prolapse complaints in women after RC, whereas a vagina- sparing approach showed significant differences only in two subscales without clinical relevance.

show abstract

Section: Discussionsupporting

confidence: 93%

Evaluation of sexual function and vaginal prolapse after radical cystectomy in women: a study to explore an under-evaluated problem

et al. 2023

View full text Add to dashboard Cite

show abstract

“…Several groups have investigated the impact of urinary diversion type (continent versus incontinent) on overall postoperative QOL, including SF. Biardeau et al and Siracusano et al found that women receiving orthotopic neobladder (ONB) were younger, more often sexually active after surgery and reported higher physical functioning on self-administered QOL surveys than women with an ileal conduit (IC) [35,36]. However, on all other components of the global functioning and BC-specific questionnaire domains, no significant differences between groups were noted [35,36].…”

Section: Survivorship and Patient Reported Outcomesmentioning

confidence: 99%

“…For example, Leminski et al [45] found that incorporating a preoperative support group led to a significantly lower incidence of postoperative depression. Depression or anxiety related to body image alterations, hypercontinence or incontinence, changes to libido and sensation, as well as anatomic vaginal changes are all major contributors to female-specific sexual health following RC [34 ▪▪ ,36,42]. Many of these issues can be addressed either by the provider or by appropriate referrals to a better-suited healthcare team member, such as a pelvic floor physical therapist or sexual medicine therapist [46].…”

Section: Survivorship and Patient Reported Outcomesmentioning

confidence: 99%

Radical cystectomy and women's sexual health – can we do better?

Escott

Avulova

Bree

et al. 2022

Current Opinion in Urology

View full text Add to dashboard Cite

Purpose of reviewFemale sexual function after radical cystectomy is a crucial, but historically overlooked component of bladder cancer survivorship. This review focuses on recent studies, which have investigated pelvic health and sexual function after radical cystectomy. We discuss modifiable factors, which may contribute to decreased sexual function after radical cystectomy and techniques, which may lead to improved outcomes.Recent findingsSexual function is important to women and there is a significant desire (and unmet need) for more perioperative counseling and discussion regarding sexual function changes and quality of life impacts. Sexual function may be altered due to a combination of hormonal changes from ovarian removal, anatomic changes from vaginal alteration, and sensation changes due to damage to the neurovascular bundle. Techniques to preserve these structures have been developed.SummarySexual function is an important component of survivorship and increasing attention is being focused on this area. Long term studies with objective measures are needed for to compare various techniques and ensure oncologic safety. Ovarian preservation, anterior vaginal wall preservation, and vaginal estrogen replacement should be carefully considered for most patients.

show abstract

“…Such changes and quality of life (QoL) of patients are commonly studied through retrospective clinical evaluations and rarely with longitudinal studies. To date, studies focusing on functional outcomes, sexual function, and health-related QoL for female patients are lacking especially in the short term, although as a whole statistically significant worse overall survival, recurrence-free survival, and cancer-specific survival are reported in comparison to male patients ( 4 ). The aim of this study was to evaluate the QoL in female patients in the first 6 months postoperatively with IC or ONB utilizing EORTC QLQ-C30 (QLQ-30) and Short-Form 36 (SF-36) questionnaires in a prospective longitudinal fashion.…”

Section: Introductionmentioning

confidence: 99%

Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study

et al. 2022

Self Cite

View full text Add to dashboard Cite

Radical cystectomy (RC) often affects patients’ life as this surgery is a traumatic and invasive event for the patients, with drawbacks on their daily, social, working, and sex life. Such changes in the quality of life (QoL) of patients are commonly studied through retrospective clinical evaluations and rarely with longitudinal studies. To date, studies focusing on functional outcomes, sexual function, and health-related QoL for female patients are lacking. We evaluated 37 patients using EORTC QLQ-C30 (QLQ-30) and Short-Form 36 (SF-36) questionnaires, before and after surgery, at 3 and 6 months of follow-up. The mean values for the emotional functioning in QLQ-C30 as well as the mental health in SF-36 were significantly higher in the ONB group compared to the IC group at 3 months of follow-up. These differences were not significant at 6 months of follow-up. At 6 months of follow-up, the ONB group showed a higher mean score in the physical and role functioning than the IC group. Although there was a statistically significant age difference at baseline of the two groups, none of the results are correlated with age, as demonstrated by Spearman’s analysis. The ONB seems to represent the most advantageous solution compared to the IC in terms of QOL at the 6-month follow-up.

show abstract

Quality of Life in Female Patients Following Ileal Neobladder and Ileal Conduit: Where Are We?

Cited by 9 publications

References 36 publications

Evaluation of sexual function and vaginal prolapse after radical cystectomy in women: a study to explore an under-evaluated problem

Evaluation of sexual function and vaginal prolapse after radical cystectomy in women: a study to explore an under-evaluated problem

Radical cystectomy and women's sexual health – can we do better?

Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study

Contact Info

Product

Resources

About