Quality of Life in Patients with Knee Osteoarthritis: A Commentary on Nonsurgical and Surgical Treatments

Abstract

Knee osteoarthritis (OA) has a significant negative impact on health-related quality of life (HRQoL). Identification of therapies that improve HRQoL in patients with knee OA may mitigate the clinical, economic, and social burden of this disease. The purpose of this commentary is to report the impact of knee OA on HRQoL, describe the change in HRQoL attributable to common knee OA interventions, and summarize findings from clinical trials of a promising therapy. Nonsurgical therapies do not reliably modify HRQoL in knee OA patients given their general inability to alleviate physical manifestations of OA. Surgical knee OA interventions generally result in good to excellent patient outcomes. However, there are significant barriers to considering surgery, which limits clinical utility. Therapies that most effectively control OA-related pain with a low risk: benefit ratio will likely have the greatest benefit on HRQoL with greater rates of patient adoption. Initial clinical trial findings suggest that less invasive joint unloading implants hold promise in bridging the therapeutic gap between nonsurgical and surgical treatments for the knee OA patient.

What interventions can improve quality of life or psychosocial factors of individuals with knee osteoarthritis? A systematic review with meta-analysis of primary outcomes from randomised controlled trials

“…The physical and psychosocial impairments in individuals with knee OA have an impact on QoL due to their influence on social interactions, mental functioning and sleep quality 7. QoL refers to the physical, psychological and social domains of health that are influenced by a person’s experiences, beliefs, expectations and perceptions 8.…”

“…Individuals with knee OA have inferior QoL compared with controls 7 9. Therefore, therapies that improve QoL in individuals with knee OA may mitigate the clinical, economic and social burden of this disorder 7. The purpose of this SR was to synthesise evidence of primary outcomes of randomised controlled trials (RCTs) examining the effect of treatment strategies on QoL or psychosocial factors in individuals with knee OA.…”

Factors Affecting Self Reported Physical Disability Among Middle Aged Patients With Knee Osteoarthritis

“…one hundred and twenty four 65 years) were randomized to therapeutic exercise (n =62) and conventional ression analysis revealed that age and BMI factors play a role in knee The present study highlights the various factors that influence physical disability and thereby demonstrates to clinical researchers and practitioners nderstanding and improving the quality of being goes beyond simply treating the Quality of life, Exercises, Osteoarthritis (OA) causes disability affecting approximately 12% of those between 25-74 years of age. [1,2]. Knee OA is multifactorial and can be divided into endogenous and exogenous risk factors.…”

“…Osteoarthritis (OA) causes disability affecting approximately 12% of those between 25 age. [1,2]. Knee OA is multifactorial and can be divided into endogenous and exogenous risk factors.…”

Gait patterns, symptoms, and function in patients with isolated tibiofemoral osteoarthritis and combined tibiofemoral and patellofemoral osteoarthritis

“…Knee osteoarthritis (OA) is a prevalent condition that is associated with considerable pain, functional limitations and reduced overall quality of life . Knee OA can occur in either the patellofemoral joint (PF), the tibiofemoral joint (TF), or both.…”