Quality of Life in Patients with Irritable Bowel Syndrome (IBS), Assessed Using the IBS–Quality of Life (IBS-QOL) Measure After 4 and 8 Weeks of Treatment with Mebeverine Hydrochloride or Pinaverium Bromide: Results of an International Prospective Observational Cohort Study in Poland, Egypt, Mexico and China

Hou, Xiaohua; Chen, Shengliang; Zhang, Yali; Sha, Weihong; Yu, Xiaofeng; Elsawah, Hesham; Afifi, Afifi Fahmy; El-Khayat, Hisham R; Nouh, Alaa; Hassan, Mohamed F.; Fatah, Ayman Abdel; Joerg, Isabel Rucker; Núñez, Juan Manuel Sánchez; Rueda, Rodolfo Osthoff; Jurkowska, Grażyna; Walczak, Michał; Małecka‐Panas, Ewa; Linke, Krzysztof; Hartleb, Marek; Solingen, Gwendolyn Janssen-van

doi:10.1007/s40261-014-0233-y

Cited by 41 publications

(30 citation statements)

References 12 publications

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“…The IBS-QOL overall score was similar in Egypt, Mexico, and Poland, but higher in China, which may be due to the cultural background in different countries, e.g. race, food, beliefs, social milieu, and health-care system [ 25 , 26 ].…”

Section: Discussionmentioning

confidence: 99%

Quality of life and depression in patients with irritable bowel syndrome

Kopczyńska¹,

Mokros²,

Pietras³

et al. 2018

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IntroductionWhile irritable bowel syndrome (IBS) is not life-threatening for most, it has enormous influence on quality of life (QOL) and mental health.AimTo evaluate the association between QOL and depressive symptoms in IBS patients.Material and methodsA total of 87 patients and 56 healthy subjects were enrolled consecutively. All participants were asked to complete self-administered questionnaires: an IBS-specific quality of life (IBS-QOL) questionnaire and the Beck Depression Inventory questionnaire (BDI).ResultsMean BDI score was higher in IBS group than in controls. IBS-QOL score was significantly lower in IBS patients compared to the control group, in all IBS-QOL domains: dysphoria (DY), interference with activity (IN), body image (BI), health worry (HW), food avoidance (FA), social relation (SR), and sexual (SX) and relationship (RL) issues. QOL DY, IN, and BI scores and overall score were significantly lower in women with IBS compared to men. We found that BDI score was significantly negatively correlated with IBS-QOL score in the domain of DY, IN, HW, FA, SR, and RL scores and overall QOL score. We also found a negative correlation between older age and health worry. RL and IN QOL scores represented the highest correlation with BDI score.ConclusionsIrritable bowel syndrome is connected with impaired patient quality of life and high prevalence of depression with high correlation rate of both parameter scores. Assessment of depression and QOL should be provided during patient visits in outpatients clinics.

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Section: Discussionmentioning

confidence: 99%

Quality of life and depression in patients with irritable bowel syndrome

Kopczyńska¹,

Mokros²,

Pietras³

et al. 2018

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“…Another recent prospective observational cohort study showed that the treatment with mebeverine hydrochloride (or with pinaverium) improved the QOL [38].…”

Section: Mebeverine and Qol In Ibsmentioning

confidence: 99%

The Use of Mebeverine in Irritable Bowel Syndrome. A Position Paper of the Romanian Society of Neurogastroenterology based on Evidence

Chira

Bățagă

et al. 2014

JGLD

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“…Irritable bowel syndrome (IBS) is a functional intestinal disorder characterised by chronic or recurrent symptoms which cannot be explained by the presence of structural, metabolic, or biochemical alterations [1]. IBS has a significant effect on the patient's quality of life [2], both personal and social, and represents an economic burden as a result of increased healthcare costs and absence from work [3,4].…”

Section: Introductionmentioning

confidence: 99%

Feasibility of Low Fermentable Oligosaccharide, Disaccharide, Monosaccharide, and Polyol Diet and Its Effects on Quality of Life in an Italian Cohort

et al. 2020

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The low Fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet has demonstrated excellent results in terms of symptom control and health-related quality of life (HRQoL) in irritable bowel syndrome (IBS) sufferers, but patients have complained about unsatisfying taste, difficulty in following the diet, and time consumption. To investigate the feasibility of the low FODMAP diet in an Italian (Sardinian) cohort, sixty consecutive eligible outpatients (11 men and 49 women) with IBS were enrolled and followed a low FODMAP diet (gluten allowed, restriction phase of four weeks, reintroduction phase of four weeks). Food habits were assessed using 24-hour dietary recall, Bristol Stool Scale for stool consistency, Visual Analogue Scale for abdominal bloating, VAS (Visual Analogue Scale) for abdominal pain, IBS Severity Scoring System for perceived disease severity, and a 12-item Short Form Survey for HRQoL (psychological component summary + mental component summary) were applied at baseline (T0) and at the end of each phase (T1-four weeks and T2-eight weeks). Statistical analysis was performed by dividing the cohort into diarrhoea-dominant IBS (IBS-D) and other IBS subtypes (selected IBS-others). Comparisons between T1 and T2 vs. T0 and T2 vs. T1 were performed. The low FODMAP diet lowered VASp (VAS pain), VASb (VAS bloating), and IBS SSS (IBS Severity Scoring System), and increased PCS (Physical Component Summary) and MCS (Mental Component Summary) in both subgroups. Bristol Stool Scale (BSS) only improved in the IBS-D subgroup. The dropout mean values for MCS were higher than treated subjects and the percentage of unemployment was lower in the dropouts. According to the dropout features, the low FODMAP diet seems to show greater feasibility for patients with more time to dedicate to the diet (unemployed, homemakers, housewives, or students), more motivation, and more severe clinical features, independent of their place of residence.

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Cited by 41 publications

References 12 publications

Quality of life and depression in patients with irritable bowel syndrome

Quality of life and depression in patients with irritable bowel syndrome

The Use of Mebeverine in Irritable Bowel Syndrome. A Position Paper of the Romanian Society of Neurogastroenterology based on Evidence

Feasibility of Low Fermentable Oligosaccharide, Disaccharide, Monosaccharide, and Polyol Diet and Its Effects on Quality of Life in an Italian Cohort

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